Substituted Pyridines as Antiparasitic AZA Teraryl Compounds

Richard R. Tidwell (Inventor), David W. Boykin (Inventor), W. David Wilson (Inventor), Reto Brun (Inventor), Karl Werbovetz (Inventor), Mohamed A. Ismail (Inventor), Reem K. Arafa (Inventor), Laixing Hu (Inventor)

Research output: Patent

Abstract

Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): ##STR00001## wherein one of A.sub.1, Y.sub.1, and Z.sub.1 is N; Ar.sub.1 is phenylene; and Ar.sub.3 is a nitrogen-containing aromatic group. An exemplary compound of Formula (III) is: ##STR00002##
LanguageEnglish
Patent number8188121
IPCA61K 31/44 (20060101)
StatePublished - 1800

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Terphenyl Compounds
Pyridines
Antiparasitic Agents
Nitrogen

Keywords

    Cite this

    Tidwell, R. R., Boykin, D. W., Wilson, W. D., Brun, R., Werbovetz, K., Ismail, M. A., ... Hu, L. (1800). IPC No. A61K 31/44 (20060101). Substituted Pyridines as Antiparasitic AZA Teraryl Compounds (Patent No. 8188121.)

    Substituted Pyridines as Antiparasitic AZA Teraryl Compounds. / Tidwell, Richard R. (Inventor); Boykin, David W. (Inventor); Wilson, W. David (Inventor); Brun, Reto (Inventor); Werbovetz, Karl (Inventor); Ismail, Mohamed A. (Inventor); Arafa, Reem K. (Inventor); Hu, Laixing (Inventor).

    IPC No.: A61K 31/44 (20060101). Patent No.: 8188121.

    Research output: Patent

    Tidwell, RR, Boykin, DW, Wilson, WD, Brun, R, Werbovetz, K, Ismail, MA, Arafa, RK & Hu, L 1800, Substituted Pyridines as Antiparasitic AZA Teraryl Compounds, Patent No. 8188121, IPC No. A61K 31/44 (20060101).
    Tidwell RR, Boykin DW, Wilson WD, Brun R, Werbovetz K, Ismail MA et al, inventors. Substituted Pyridines as Antiparasitic AZA Teraryl Compounds. A61K 31/44 (20060101). 1800
    Tidwell, Richard R. (Inventor) ; Boykin, David W. (Inventor) ; Wilson, W. David (Inventor) ; Brun, Reto (Inventor) ; Werbovetz, Karl (Inventor) ; Ismail, Mohamed A. (Inventor) ; Arafa, Reem K. (Inventor) ; Hu, Laixing (Inventor). / Substituted Pyridines as Antiparasitic AZA Teraryl Compounds. IPC No.: A61K 31/44 (20060101). Patent No.: 8188121.
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    abstract = "Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): ##STR00001## wherein one of A.sub.1, Y.sub.1, and Z.sub.1 is N; Ar.sub.1 is phenylene; and Ar.sub.3 is a nitrogen-containing aromatic group. An exemplary compound of Formula (III) is: ##STR00002##",
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    T1 - Substituted Pyridines as Antiparasitic AZA Teraryl Compounds

    AU - Tidwell,Richard R.

    AU - Boykin,David W.

    AU - Wilson,W. David

    AU - Brun,Reto

    AU - Werbovetz,Karl

    AU - Ismail,Mohamed A.

    AU - Arafa,Reem K.

    AU - Hu,Laixing

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    PY - 1800

    Y1 - 1800

    N2 - Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): ##STR00001## wherein one of A.sub.1, Y.sub.1, and Z.sub.1 is N; Ar.sub.1 is phenylene; and Ar.sub.3 is a nitrogen-containing aromatic group. An exemplary compound of Formula (III) is: ##STR00002##

    AB - Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. The compounds include those of Formula (III): ##STR00001## wherein one of A.sub.1, Y.sub.1, and Z.sub.1 is N; Ar.sub.1 is phenylene; and Ar.sub.3 is a nitrogen-containing aromatic group. An exemplary compound of Formula (III) is: ##STR00002##

    KW - 514/340 544/405 546/257

    M3 - Patent

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    ER -