Novel Curcumin Analogues and Uses Thereof

Kuo-Hsiung Lee (Inventor), Li Lin (Inventor), Charles C-Y Shih (Inventor), Ching-Yuan Su (Inventor), Junko Ishida (Inventor), Hironori Ohtsu (Inventor), Hui-Kang Wang (Inventor), Hideji Itokawa (Inventor), Chawnshang Chang (Inventor)

Research output: Patent

Abstract

The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.
LanguageEnglish
Patent number7709535
IPCA01N 35/00 (20060101); C07C 49/00 (20060101)
StatePublished - 1800

Fingerprint

Androgen Receptor Antagonists
Curcumin
Spermatogenesis
Androgens
Hirsutism
Drug Compounding
Alopecia
Acne Vulgaris
Skin Neoplasms
Antineoplastic Agents
Colonic Neoplasms
Prostatic Neoplasms
Neoplasms

Keywords

    Cite this

    Lee, K-H., Lin, L., Shih, C. C-Y., Su, C-Y., Ishida, J., Ohtsu, H., ... Chang, C. (1800). IPC No. A01N 35/00 (20060101); C07C 49/00 (20060101). Novel Curcumin Analogues and Uses Thereof. (Patent No. 7709535).

    Novel Curcumin Analogues and Uses Thereof. / Lee, Kuo-Hsiung (Inventor); Lin, Li (Inventor); Shih, Charles C-Y (Inventor); Su, Ching-Yuan (Inventor); Ishida, Junko (Inventor); Ohtsu, Hironori (Inventor); Wang, Hui-Kang (Inventor); Itokawa, Hideji (Inventor); Chang, Chawnshang (Inventor).

    IPC No.: A01N 35/00 (20060101); C07C 49/00 (20060101). Patent No.: 7709535.

    Research output: Patent

    Lee, K-H, Lin, L, Shih, CC-Y, Su, C-Y, Ishida, J, Ohtsu, H, Wang, H-K, Itokawa, H & Chang, C 1800, Novel Curcumin Analogues and Uses Thereof, Patent No. 7709535, IPC No. A01N 35/00 (20060101); C07C 49/00 (20060101).
    Lee K-H, Lin L, Shih CC-Y, Su C-Y, Ishida J, Ohtsu H et al, inventors. Novel Curcumin Analogues and Uses Thereof. A01N 35/00 (20060101); C07C 49/00 (20060101). 1800.
    Lee, Kuo-Hsiung (Inventor) ; Lin, Li (Inventor) ; Shih, Charles C-Y (Inventor) ; Su, Ching-Yuan (Inventor) ; Ishida, Junko (Inventor) ; Ohtsu, Hironori (Inventor) ; Wang, Hui-Kang (Inventor) ; Itokawa, Hideji (Inventor) ; Chang, Chawnshang (Inventor). / Novel Curcumin Analogues and Uses Thereof. IPC No.: A01N 35/00 (20060101); C07C 49/00 (20060101). Patent No.: 7709535.
    @misc{8cb90f0ee0cf42b7913cfd95126259b3,
    title = "Novel Curcumin Analogues and Uses Thereof",
    abstract = "The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.",
    keywords = "514/545,675,679,705,348 560/53 568/36,325",
    author = "Kuo-Hsiung Lee and Li Lin and Shih, {Charles C-Y} and Ching-Yuan Su and Junko Ishida and Hironori Ohtsu and Hui-Kang Wang and Hideji Itokawa and Chawnshang Chang",
    note = "Status: published applicationnumber: 12/030,691 usclass: 514/705 ; 514/679; 568/325 applicationnumber: 12/030,691; 7709535; A01N 35/00 (20060101); C07C 49/00 (20060101)",
    year = "1800",
    language = "English",
    type = "Patent",

    }

    TY - PAT

    T1 - Novel Curcumin Analogues and Uses Thereof

    AU - Lee, Kuo-Hsiung

    AU - Lin, Li

    AU - Shih, Charles C-Y

    AU - Su, Ching-Yuan

    AU - Ishida, Junko

    AU - Ohtsu, Hironori

    AU - Wang, Hui-Kang

    AU - Itokawa, Hideji

    AU - Chang, Chawnshang

    N1 - Status: published applicationnumber: 12/030,691 usclass: 514/705 ; 514/679; 568/325 applicationnumber: 12/030,691

    PY - 1800

    Y1 - 1800

    N2 - The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.

    AB - The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.

    KW - 514/545,675,679,705,348 560/53 568/36,325

    M3 - Patent

    M1 - 7709535

    ER -