Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors

Paul E. Monahan (Inventor), Richard Jude Samulski (Inventor), Joseph E. Rabinowitz (Inventor)

Research output: ResearchPatent

Abstract

The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).
LanguageEnglish
Patent number7923436
IPCA61K 48/00 (20060101); A61K 39/23 (20060101)
StatePublished - 1800

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Dependovirus
Parvovirus
Therapeutics
Virus Assembly
Genetic Therapy
Sutures
Transplants
Genes

Keywords

    Cite this

    Monahan, P. E., Samulski, R. J., & Rabinowitz, J. E. (1800). IPC No. A61K 48/00 (20060101); A61K 39/23 (20060101). Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors (Patent No. 7923436.)

    Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors. / Monahan, Paul E. (Inventor); Samulski, Richard Jude (Inventor); Rabinowitz, Joseph E. (Inventor).

    IPC No.: A61K 48/00 (20060101); A61K 39/23 (20060101). Patent No.: 7923436.

    Research output: ResearchPatent

    Monahan, PE, Samulski, RJ & Rabinowitz, JE 1800, Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors, Patent No. 7923436, IPC No. A61K 48/00 (20060101); A61K 39/23 (20060101).
    Monahan PE, Samulski RJ, Rabinowitz JE, inventors. Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors. A61K 48/00 (20060101); A61K 39/23 (20060101). 1800
    Monahan, Paul E. (Inventor) ; Samulski, Richard Jude (Inventor) ; Rabinowitz, Joseph E. (Inventor). / Methods and Compounds for Controlled Release of Recombinant Parvovirus Vectors. IPC No.: A61K 48/00 (20060101); A61K 39/23 (20060101). Patent No.: 7923436.
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    abstract = "The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).",
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    AU - Rabinowitz,Joseph E.

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    AB - The invention uses recombinant parvoviruses, and particularly recombinant adeno-associated virus (rAAV) to deliver genes and DNA sequences for gene therapy following manipulation of the therapeutic virus for packaging and transport. The invention delivers therapeutic viral vectors via rAAV affixed to support matrixes (i.e., sutures, surgically implantable materials, grafts, and the like).

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