Magnetic resonance imaging of the cirrhotic liver: Diagnosis of hepatocellular carcinoma and evaluation of response to treatment –part 1

Miguel Ramalho, António P. Matos, Mamdoh Alobaidy, Fernanda Velloni, Ersan Altun, Richard C. Semelka

Research output: Contribution to journalReview article

  • 4 Citations

Abstract

The combination of arterial phase hyperenhancement and delayed wash-out allows a definitive diagnosis of hepatocellular carcinoma (HCC) in patients with liver cirrhosis or chronic liver disease, without the requirement for confirmatory biopsy. That pattern is highly specific and has been endorsed in Western and Asian diagnostic guidelines. However, the sensitivity of the combination is relatively low for small HCCs. In this twopart review paper, we will address MRI of the cirrhotic liver. In this first part, we provide a brief background on liver cirrhosis and HCC, followed by descriptions of imaging surveillance of liver cirrhosis and the diagnostic performance of the different imaging modalities used in clinical settings. We then describe some of the requirements for the basic MRI technique, as well as the standard MRI protocol, and provide a detailed description of the appearance of various types of hepatocellular nodules encountered in the setting of the carcinogenic pathway in the cirrhotic liver, ranging from regenerative nodules to HCC.

Translated title of the contributionMagnetic resonance imaging of the cirrhotic liver : Diagnosis of hepatocellular carcinoma and evaluation of response to treatment –part 1
LanguagePortuguese
Pages38-47
Number of pages10
JournalRadiologia Brasileira
Volume50
Issue number1
DOIs
StatePublished - Jan 1 2017

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Liver Cirrhosis
Hepatocellular Carcinoma
Magnetic Resonance Imaging
Liver
Liver Diseases
Chronic Disease
Therapeutics
Guidelines
Biopsy

Keywords

  • Contrast media
  • Image enhancement
  • Liver Cirrhosis
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Ressonância magnética do fígado cirrótico : Diagnóstico de carcinoma hepatocelular e avaliação da resposta ao tratamento –Parte 1. / Ramalho, Miguel; Matos, António P.; Alobaidy, Mamdoh; Velloni, Fernanda; Altun, Ersan; Semelka, Richard C.

In: Radiologia Brasileira, Vol. 50, No. 1, 01.01.2017, p. 38-47.

Research output: Contribution to journalReview article

Ramalho, Miguel ; Matos, António P. ; Alobaidy, Mamdoh ; Velloni, Fernanda ; Altun, Ersan ; Semelka, Richard C./ Ressonância magnética do fígado cirrótico : Diagnóstico de carcinoma hepatocelular e avaliação da resposta ao tratamento –Parte 1. In: Radiologia Brasileira. 2017 ; Vol. 50, No. 1. pp. 38-47
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