Dietary determinants of cadmium exposure in the Strong Heart Family Study

Pablo Olmedo, Maria Grau-Perez, Amanda Fretts, Maria Tellez-Plaza, Fernando Gil, Fawn Yeh, Jason G. Umans, Kevin A. Francesconi, Walter Goessler, Nora Franceschini, Elisa T. Lee, Lyle G. Best, Shelley A. Cole, Barbara V. Howard, Ana Navas-Acien

Research output: Research - peer-reviewArticle

  • 2 Citations

Abstract

Urinary cadmium (Cd) concentrations in the Strong Heart Family Study (SHFS) participants are higher than in the general US population. This difference is unlikely to be related to tobacco smoking. We evaluated the association of consumption of processed meats and other dietary products with urinary Cd concentrations in the SHFS, a family-based study conducted in American Indian communities. We included 1725 participants with urine Cd concentrations (standardized to urine creatinine) and food frequency questionnaire data grouped in 24 categories, including processed meat. Median (IQR) urinary Cd concentrations were 0.42 (0.20–0.85) μg/g creatinine. The age, sex, smoking, education, center, body mass index, and total kcal adjusted geometric mean ratio (GMR) (95%CI) of urinary cadmium concentrations per IQR increase in each dietary category was 1.16 (1.04–1.29) for processed meat, 1.10 (1.00–1.21) for fries and chips, 0.87 (0.80–0.95) for dairy products, and 0.89 (0.82–0.97) for fruit juices. The results remained similar after further adjustment for the dietary categories associated with urinary Cd in the previous model except for fries and chips, which was no longer statistically significant. These findings revealed the potential importance of processed meat products as a dietary source of cadmium.

LanguageEnglish (US)
Pages239-246
Number of pages8
JournalFood and Chemical Toxicology
Volume100
DOIs
StatePublished - Feb 1 2017

Fingerprint

family studies
cadmium
heart
Cadmium
processed meat
Meats
Meat
creatinine
urine
Creatinine
Smoking
Urine
smoking (habit)
American Indians
smoking (food products)
food frequency questionnaires
fruit juices
meat products
dairy products
body mass index

Keywords

  • American Indians
  • Association analysis
  • Cadmium
  • Diet
  • Epidemiology
  • Meat

ASJC Scopus subject areas

  • Food Science
  • Toxicology

Cite this

Olmedo, P., Grau-Perez, M., Fretts, A., Tellez-Plaza, M., Gil, F., Yeh, F., ... Navas-Acien, A. (2017). Dietary determinants of cadmium exposure in the Strong Heart Family Study. Food and Chemical Toxicology, 100, 239-246. DOI: 10.1016/j.fct.2016.12.015

Dietary determinants of cadmium exposure in the Strong Heart Family Study. / Olmedo, Pablo; Grau-Perez, Maria; Fretts, Amanda; Tellez-Plaza, Maria; Gil, Fernando; Yeh, Fawn; Umans, Jason G.; Francesconi, Kevin A.; Goessler, Walter; Franceschini, Nora; Lee, Elisa T.; Best, Lyle G.; Cole, Shelley A.; Howard, Barbara V.; Navas-Acien, Ana.

In: Food and Chemical Toxicology, Vol. 100, 01.02.2017, p. 239-246.

Research output: Research - peer-reviewArticle

Olmedo, P, Grau-Perez, M, Fretts, A, Tellez-Plaza, M, Gil, F, Yeh, F, Umans, JG, Francesconi, KA, Goessler, W, Franceschini, N, Lee, ET, Best, LG, Cole, SA, Howard, BV & Navas-Acien, A 2017, 'Dietary determinants of cadmium exposure in the Strong Heart Family Study' Food and Chemical Toxicology, vol 100, pp. 239-246. DOI: 10.1016/j.fct.2016.12.015
Olmedo P, Grau-Perez M, Fretts A, Tellez-Plaza M, Gil F, Yeh F et al. Dietary determinants of cadmium exposure in the Strong Heart Family Study. Food and Chemical Toxicology. 2017 Feb 1;100:239-246. Available from, DOI: 10.1016/j.fct.2016.12.015
Olmedo, Pablo ; Grau-Perez, Maria ; Fretts, Amanda ; Tellez-Plaza, Maria ; Gil, Fernando ; Yeh, Fawn ; Umans, Jason G. ; Francesconi, Kevin A. ; Goessler, Walter ; Franceschini, Nora ; Lee, Elisa T. ; Best, Lyle G. ; Cole, Shelley A. ; Howard, Barbara V. ; Navas-Acien, Ana. / Dietary determinants of cadmium exposure in the Strong Heart Family Study. In: Food and Chemical Toxicology. 2017 ; Vol. 100. pp. 239-246
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