Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer

Zachary A P Wintrob, Jeffrey P. Hammel, George K. Nimako, Zahra S. Fayazi, Dan P. Gaile, Erin E. Davis, Alan Forrest, Alice C. Ceacareanu

Research output: Research - peer-reviewArticle

  • 2 Citations

Abstract

Injectable insulin use may interfere with pro-inflammatory cytokines’ production and, thus, play a role in the activation of tumor-associated macrophages - a process mainly influenced by inflammatory C–C chemokines. The data presented shows the relationship between pre-existing use of injectable insulin in women diagnosed with breast cancer and type 2 diabetes mellitus, the inflammatory C–C chemokine profiles at the time of breast cancer diagnosis, and subsequent cancer outcomes. A Pearson correlation analysis stratified by insulin use and controls is also provided. We present the observed relationship between the investigated C–C chemokines and between each of these biomarkers and previously reported adipokines levels in this study population [1].

LanguageEnglish (US)
Pages446-458
Number of pages13
JournalData in Brief
Volume11
DOIs
StatePublished - Apr 1 2017

Fingerprint

chronic illness
cancer
activation
time

Keywords

  • Breast cancer
  • C-C chemokines
  • Cancer prognosis
  • CCL-2
  • CCL-3
  • CCL-4
  • CCL-5
  • Diabetes
  • Inflammation
  • Inflammatory cytokines
  • Insulin
  • Tumor-associated macrophages

ASJC Scopus subject areas

  • Education
  • General

Cite this

Wintrob, Z. A. P., Hammel, J. P., Nimako, G. K., Fayazi, Z. S., Gaile, D. P., Davis, E. E., ... Ceacareanu, A. C. (2017). Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer. Data in Brief, 11, 446-458. DOI: 10.1016/j.dib.2017.02.045

Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer. / Wintrob, Zachary A P; Hammel, Jeffrey P.; Nimako, George K.; Fayazi, Zahra S.; Gaile, Dan P.; Davis, Erin E.; Forrest, Alan; Ceacareanu, Alice C.

In: Data in Brief, Vol. 11, 01.04.2017, p. 446-458.

Research output: Research - peer-reviewArticle

Wintrob, ZAP, Hammel, JP, Nimako, GK, Fayazi, ZS, Gaile, DP, Davis, EE, Forrest, A & Ceacareanu, AC 2017, 'Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer' Data in Brief, vol 11, pp. 446-458. DOI: 10.1016/j.dib.2017.02.045
Wintrob ZAP, Hammel JP, Nimako GK, Fayazi ZS, Gaile DP, Davis EE et al. Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer. Data in Brief. 2017 Apr 1;11:446-458. Available from, DOI: 10.1016/j.dib.2017.02.045
Wintrob, Zachary A P ; Hammel, Jeffrey P. ; Nimako, George K. ; Fayazi, Zahra S. ; Gaile, Dan P. ; Davis, Erin E. ; Forrest, Alan ; Ceacareanu, Alice C./ Data report on inflammatory C–C chemokines among insulin-using women with diabetes mellitus and breast cancer. In: Data in Brief. 2017 ; Vol. 11. pp. 446-458
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