Compositions and Methods for Detecting Cancer

Teresa A. Brentnall (Inventor), Ru Chen (Inventor), Katherine L. Pogue-Geile (Inventor), David C. Whitcomb (Inventor), Mary Patricia Bronner (Inventor), Carol A. Otey (Inventor)

Research output: ResearchPatent

Abstract

The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
LanguageEnglish
Patent number7851144
IPCC12Q 1/00 (20060101); G01N 33/574 (20060101)
StatePublished - 1800

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Neoplasms
Nucleic Acid Probes
Neoplasm Staging
Nucleic Acids
Messenger RNA
Antibodies
Genes
Proteins

Cite this

Brentnall, T. A., Chen, R., Pogue-Geile, K. L., Whitcomb, D. C., Bronner, M. P., & Otey, C. A. (1800). IPC No. C12Q 1/00 (20060101); G01N 33/574 (20060101). Compositions and Methods for Detecting Cancer (Patent No. 7851144.)

Compositions and Methods for Detecting Cancer. / Brentnall, Teresa A. (Inventor); Chen, Ru (Inventor); Pogue-Geile, Katherine L. (Inventor); Whitcomb, David C. (Inventor); Bronner, Mary Patricia (Inventor); Otey, Carol A. (Inventor).

IPC No.: C12Q 1/00 (20060101); G01N 33/574 (20060101). Patent No.: 7851144.

Research output: ResearchPatent

Brentnall, TA, Chen, R, Pogue-Geile, KL, Whitcomb, DC, Bronner, MP & Otey, CA 1800, Compositions and Methods for Detecting Cancer, Patent No. 7851144, IPC No. C12Q 1/00 (20060101); G01N 33/574 (20060101).
Brentnall TA, Chen R, Pogue-Geile KL, Whitcomb DC, Bronner MP, Otey CA, inventors. Compositions and Methods for Detecting Cancer. C12Q 1/00 (20060101); G01N 33/574 (20060101). 1800
Brentnall, Teresa A. (Inventor) ; Chen, Ru (Inventor) ; Pogue-Geile, Katherine L. (Inventor) ; Whitcomb, David C. (Inventor) ; Bronner, Mary Patricia (Inventor) ; Otey, Carol A. (Inventor). / Compositions and Methods for Detecting Cancer. IPC No.: C12Q 1/00 (20060101); G01N 33/574 (20060101). Patent No.: 7851144.
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abstract = "The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.",
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AU - Bronner,Mary Patricia

AU - Otey,Carol A.

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N2 - The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.

AB - The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.

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