(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzyme

Jing‐Jer ‐J Lin, Aziz Sancar

Research output: Contribution to journal › Review article

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Abstract

Nucleotide excision repair is the major pathway for removing damage from DNA. (A)BC excinuclease is the nuclease activity which initiates nucleotide excision repair in Escherichia coli. in this review, we focus on current understanding of the structure‐function of the enzyme and the reaction mechanism of the repair pathway. In addition, recent biochemical studies on preferential repair of actively transcribed genes in E. coli are summarized.

LanguageEnglish (US)
Pages2219-2224
Number of pages6
JournalMolecular microbiology
Volume6
Issue number16
DOIs
StatePublished - Jan 1 1992

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DNA Repair
Escherichia coli
Enzymes
DNA Damage
Genes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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(A)BC excinuclease : the Escherichia coli nucleotide excision repair enzyme. / Lin, Jing‐Jer ‐J; Sancar, Aziz.

In: Molecular microbiology, Vol. 6, No. 16, 01.01.1992, p. 2219-2224.

Research output: Contribution to journal › Review article

Lin, JJJ & Sancar, A 1992, '(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzyme', Molecular microbiology, vol. 6, no. 16, pp. 2219-2224. https://doi.org/10.1111/j.1365-2958.1992.tb01398.x
Lin JJJ, Sancar A. (A)BC excinuclease: the Escherichia coli nucleotide excision repair enzyme. Molecular microbiology. 1992 Jan 1;6(16):2219-2224. https://doi.org/10.1111/j.1365-2958.1992.tb01398.x
Lin, Jing‐Jer ‐J ; Sancar, Aziz. / (A)BC excinuclease : the Escherichia coli nucleotide excision repair enzyme. In: Molecular microbiology. 1992 ; Vol. 6, No. 16. pp. 2219-2224.
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