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2018
11 Citations

A DNA methylation biomarker of alcohol consumption

Liu, C. , Marioni, R. E. , Hedman, A. K. , Pfeiffer, L. , Tsai, P. C. , Reynolds, L. M. , Just, A. C. , Duan, Q. , Boer, C. G. , Tanaka, T. , Elks, C. E. , Aslibekyan, S. , Brody, J. A. , Kühnel, B. , Herder, C. , Almli, L. M. , Zhi, D. , Wang, Y. , Huan, T. , Yao, C. & 30 others Mendelson, M. M., Joehanes, R., Liang, L., Love, S. A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H., Strauch, K., Peters, A., Visscher, P. M., Wray, N. R., Guo, X., Wiggins, K. L., Smith, A. K., Binder, E. B., Ressler, K. J., Irvin, M. R., Absher, D. M., Hernandez, D., Ferrucci, L., Bandinelli, S., Lohman, K., Ding, J., Trevisi, L., Gustafsson, S., Sandling, J. H., Stolk, L. & Uitterlinden, A. G. Feb 1 2018 In : Molecular Psychiatry. 23, 2, p. 422-433 12 p.

Research output: Contribution to journalArticle

DNA Methylation
Alcohol Drinking
Biomarkers
Alcohols
Methylation
2017
9 Citations

A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL

Sofer, T., Heller, R., Bogomolov, M., Avery, C. L., Graff, M., North, K. E., Reiner, A. P., Thornton, T. A., Rice, K., Benjamini, Y., Laurie, C. C. & Kerr, K. F. Apr 1 2017 In : Genetic Epidemiology. 41, 3, p. 251-258 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans
Single Nucleotide Polymorphism
Health
Genetic Association Studies
2 Citations

Association of cardiometabolic genes with arsenic metabolism biomarkers in American Indian communities: The strong heart family study (SHFS)

Balakrishnan, P., Vaidya, D., Franceschini, N., Saroja Voruganti, V., Gribble, M. O., Haack, K., Laston, S., Umans, J. G., Francesconi, K. A., Goessler, W., North, K. E., Lee, E., Yracheta, J., Best, L. G., Maccluer, J. W., Kent, J., Cole, S. A. & Navas-Acien, A. Jan 1 2017 In : Environmental Health Perspectives. 125, 1, p. 15-22 8 p.

Research output: Contribution to journalArticle

North American Indians
Arsenic
Biomarkers
Genes
Cacodylic Acid
2 Citations

BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort

Graff, M., North, K. E., Richardson, A. S., Young, K. L., Mazul, A. L., Highland, H. M., Mohlke, K. L., Lange, L. A., Lange, E. M., Mullan Harris, K. & Gordon-Larsen, P. May 1 2017 In : International Journal of Obesity. 41, 5, p. 759-768 10 p.

Research output: Contribution to journalArticle

Body Mass Index
Single Nucleotide Polymorphism
Hispanic Americans
African Americans
Obesity
2 Citations

Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts

De, R. , Verma, S. S. , Holzinger, E. , Hall, M. , Burt, A. , Carrell, D. S. , Crosslin, D. R. , Jarvik, G. P. , Kuivaniemi, H. , Kullo, I. J. , Lange, L. A. , Lanktree, M. B. , Larson, E. B. , North, K. E. , Reiner, A. P. , Tragante, V. , Tromp, G. , Wilson, J. G. , Asselbergs, F. W. , Drenos, F. & 4 others Moore, J. H., Ritchie, M. D., Keating, B. & Gilbert-Diamond, D. Feb 1 2017 In : Human Genetics. 136, 2, p. 165-178 14 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Lipids
Genes
Triglycerides
LDL Cholesterol
2016

A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women

Taylor, K. C. , Evans, D. S. , Edwards, D. R. V. , Edwards, T. L. , Sofer, T. , Li, G. , Liu, Y. , Franceschini, N. , Jackson, R. D. , Giri, A. , Donneyong, M. , Psaty, B. , Rotter, J. I. , LaCroix, A. Z. , Jordan, J. M. , Robbins, J. A. , Lewis, B. , Stefanick, M. L. , Liu, Y. , Garcia, M. & 3 others Harris, T., Cauley, J. A. & North, K. E. Dec 1 2016 In : Bone Reports. 5, p. 233-242 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
African Americans
Meta-Analysis
Single Nucleotide Polymorphism
Health
33 Citations

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Sampson, J. N. , Wheeler, W. A. , Yeager, M. , Panagiotou, O. , Wang, Z. , Berndt, S. I. , Lan, Q. , Abnet, C. C. , Amundadottir, L. T. , Figueroa, J. D. , Landi, M. T. , Mirabello, L. , Savage, S. A. , Taylor, P. R. , De Vivo, I. , McGlynn, K. A. , Purdue, M. P. , Rajaraman, P. , Adami, H. O. , Ahlbom, A. & 30 others Albanes, D., Amary, M. F., An, S. J., Andersson, U., Andriole, G., Andrulis, I. L., Angelucci, E., Ansell, S. M., Arici, C., Armstrong, B. K., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Becker, N., Benavente, Y., Benhamou, S., Berg, C., Van Den Berg, D., Bernstein, L., Bertrand, K. A., Birmann, B. M., Black, A., Boeing, H., Boffetta, P., Boutron-Ruault, M. C., Bracci, P. M., Brinton, L. & Brooks-Wilson, A. R. Jan 1 2016 In : Journal of the National Cancer Institute. 107, 12, djv279

Research output: Contribution to journalArticle

Genome-Wide Association Study
Smoking
Neoplasms
Lung Neoplasms
Confidence Intervals
11 Citations

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S. , Jeff, J. M. , Chu, A. Y. , Bragg-Gresham, J. L. , Van Dongen, J. , Huffman, J. E. , Ahluwalia, T. S. , Cadby, G. , Eklund, N. , Eriksson, J. , Esko, T. , Feitosa, M. F. , Goel, A. , Gorski, M. , Hayward, C. , Heard-Costa, N. L. , Jackson, A. U. , Jokinen, E. , Kanoni, S. , Kristiansson, K. & 30 others Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Standáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., Van Der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E. & Couto Alves, A. Nov 23 2016 In : Nature Communications. 7, 13357

Research output: Contribution to journalArticle

loci
Principal Component Analysis
phenotype
Meta-Analysis
Phenotype

AS3MT, locus 10q24 and arsenic metabolism biomarkers in American Indians: The strong heart family study

Balakrishnan, P., Vaidya, D., Franceschini, N., Voruganti, V. S., Gribble, M., Haack, K., Laston, S., Umans, J., Francesconi, K., Goessler, W., North, K., Lee, E., Yracheta, J., Best, L., Maccluer, J., Kent, J., Cole, S. & Navas-Acien, A. Jan 1 2016 Arsenic Research and Global Sustainability - Proceedings of the 6th International Congress on Arsenic in the Environment, AS 2016. CRC Press/Balkema, p. 443-445 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Arsenic
Biomarkers
Metabolism
biomarker
arsenic
3 Citations

Association of Forced Vital Capacity with the Developmental Gene NCOR2

SpiroMeta consortium, CHARGE consortium. & Full list of collaborators in the CHARGE and SpiroMeta consortia Feb 1 2016 In : PloS one. 11, 2, e0147388

Research output: Contribution to journalArticle

Developmental Genes
Vital Capacity
Genes
lungs
Lung
2 Citations

Comparison of 2 models for gene-environment interactions: An example of simulated gene-medication interactions on systolic blood pressure in family-based data

Fernández-Rhodes, L., Hodonsky, C. J., Graff, M., Love, S. A. M., Howard, A. G., Seyerle, A. A., Avery, C. L., Chittoor, G., Franceschini, N., Voruganti, V. S., Young, K., O'Connell, J. R., North, K. E. & Justice, A. E. Jan 1 2016 In : BMC Proceedings. 10, 65

Research output: Contribution to journalArticle

Gene-Environment Interaction
Blood pressure
Single Nucleotide Polymorphism
Genes
Blood Pressure
1 Citations
National Longitudinal Study of Adolescent Health
Glycosylated Hemoglobin A
Young Adult
Body Mass Index
Hispanic Americans
14 Citations

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Machiela, M. J. , Lan, Q. , Slager, S. L. , Vermeulen, R. C. H. , Teras, L. R. , Camp, N. J. , Cerhan, J. R. , Spinelli, J. J. , Wang, S. S. , Nieters, A. , Vijai, J. , Yeager, M. , Wang, Z. , Ghesquières, H. , McKay, J. , Conde, L. , de Bakker, P. I. W. , Cox, D. G. , Burdett, L. , Monnereau, A. & 30 others Flowers, C. R., De Roos, A. J., Brooks-Wilson, A. R., Giles, G. G., Melbye, M., Gu, J., Jackson, R. D., Kane, E., Purdue, M. P., Vajdic, C. M., Albanes, D., Kelly, R. S., Zucca, M., Bertrand, K. A., Zeleniuch-Jacquotte, A., Lawrence, C., Hutchinson, A., Zhi, D., Habermann, T. M., Link, B. K., Novak, A. J., Dogan, A., Asmann, Y. W., Liebow, M., Thompson, C. A., Ansell, S. M., Witzig, T. E., Tilly, H., Haioun, C. & Molina, T. J. Apr 15 2016 In : Human molecular genetics. 25, 8, p. 1663-1676 14 p.

Research output: Contribution to journalArticle

Telomere
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
44 Citations

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

Conomos, M. P. , Laurie, C. A. , Stilp, A. M. , Gogarten, S. M. , McHugh, C. P. , Nelson, S. C. , Sofer, T. , Fernández-Rhodes, L. , Justice, A. E. , Graff, M. , Young, K. L. , Seyerle, A. A. , Avery, C. L. , Taylor, K. D. , Rotter, J. I. , Talavera, G. A. , Daviglus, M. L. , Wassertheil-Smoller, S. , Schneiderman, N. , Heiss, G. & 17 others Kaplan, R. C., Franceschini, N., Reiner, A. P., Shaffer, J. R., Barr, R. G., Kerr, K. F., Browning, S. R., Browning, B. L., Weir, B. S., Avilés-Santa, M. L., Papanicolaou, G. J., Lumley, T., Szpiro, A. A., North, K. E., Rice, K., Thornton, T. A. & Laurie, C. C. Jan 7 2016 In : American Journal of Human Genetics. 98, 1, p. 165-184 20 p.

Research output: Contribution to journalArticle

Genetic Association Studies
Hispanic Americans
Linear Models
Genome-Wide Association Study
Health
1 Citations

Genetic variation near IRS1 is associated with adiposity and a favorable metabolic profile in U.S. Hispanics/Latinos

Qi, Q., Gogarten, S. M., Emery, L. S., Louie, T., Stilp, A., Cai, J., Schneiderman, N., Avilés-Santa, M. L., Kaplan, R. C., North, K. E., Laurie, C. C., Loos, R. J. F. & Isasi, C. R. Nov 1 2016 In : Obesity. 24, 11, p. 2407-2413 7 p.

Research output: Contribution to journalArticle

Metabolome
Adiposity
Hispanic Americans
Adipose Tissue
Alleles

Genome-wide association of trajectories of systolic blood pressure change

Justice, A. E., Howard, A. G., Chittoor, G., Fernandez-Rhodes, L., Graff, M., Voruganti, V. S., Diao, G., Love, S. A. M., Franceschini, N., O'Connell, J. R., Avery, C. L., Young, K. L. & North, K. E. Jan 1 2016 In : BMC Proceedings. 10, 56

Research output: Contribution to journalArticle

Blood pressure
Genes
Trajectories
Genome
Blood Pressure
12 Citations

Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease

Offenbacher, S., Divaris, K., Barros, S. P., Moss, K. L., Marchesan, J. T., Morelli, T., Zhang, S., Kim, S., Sun, L., Beck, J. D., Laudes, M., Munz, M., Schaefer, A. S. & North, K. E. May 15 2016 In : Human Molecular Genetics. 25, 10, p. 2113-2129 17 p., ddw069

Research output: Contribution to journalArticle

Chronic Periodontitis
Genome-Wide Association Study
Periodontal Diseases
Aggressive Periodontitis
snRNP Core Proteins
14 Citations

Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans

Schick, U. M. , Jain, D. , Hodonsky, C. J. , Morrison, J. V. , Davis, J. P. , Brown, L. , Sofer, T. , Conomos, M. P. , Schurmann, C. , McHugh, C. P. , Nelson, S. C. , Vadlamudi, S. , Stilp, A. , Plantinga, A. , Baier, L. , Bien, S. A. , Gogarten, S. M. , Laurie, C. A. , Taylor, K. D. , Liu, Y. & 18 others Auer, P. L., Franceschini, N., Szpiro, A., Rice, K., Kerr, K. F., Rotter, J. I., Hanson, R. L., Papanicolaou, G., Rich, S. S., Loos, R. J. F., Browning, B. L., Browning, S. R., Weir, B. S., Laurie, C. C., Mohlke, K. L., North, K. E., Thornton, T. A. & Reiner, A. P. Feb 4 2016 In : American Journal of Human Genetics. 98, 2, p. 229-242 14 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Platelet Count
Hispanic Americans
Hemostasis
Protein Binding
2 Citations

Influence of SNP∗SNP interaction on BMI in European American adolescents: Findings from the National Longitudinal Study of Adolescent Health

Young, K. L., Graff, M., North, K. E., Richardson, A. S., Bradfield, J. P., Grant, S. F. A., Lange, L. A., Lange, E. M., Harris, K. M. & Gordon-Larsen, P. Apr 1 2016 In : Pediatric Obesity. 11, 2, p. 95-101 7 p.

Research output: Contribution to journalArticle

National Longitudinal Study of Adolescent Health
Single Nucleotide Polymorphism
Body Mass Index
Genes
Weight Gain
4 Citations

Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity

Sajuthi, S. P. , Sharma, N. K. , Chou, J. W. , Palmer, N. D. , McWilliams, D. R. , Beal, J. , Comeau, M. E. , Ma, L. , Calles-Escandon, J. , Demons, J. , Rogers, S. , Cherry, K. , Menon, L. , Kouba, E. , Davis, D. , Burris, M. , Byerly, S. J. , Ng, M. C. Y. , Maruthur, N. M. , Patel, S. R. & 16 others Bielak, L. F., Lange, L. A., Guo, X., Sale, M. M., Chan, K. H. K., Monda, K. L., Chen, G. K., Taylor, K., Palmer, C., Edwards, T. L., North, K. E., Haiman, C. A., Bowden, D. W., Freedman, B. I., Langefeld, C. D. & Das, S. K. Aug 1 2016 In : Human Genetics. 135, 8, p. 869-880 12 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
African Americans
Type 2 Diabetes Mellitus
Adipose Tissue
Obesity
13 Citations

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia

Berndt, S. I. , Camp, N. J. , Skibola, C. F. , Vijai, J. , Wang, Z. , Gu, J. , Nieters, A. , Kelly, R. S. , Smedby, K. E. , Monnereau, A. , Cozen, W. , Cox, A. , Wang, S. S. , Lan, Q. , Teras, L. R. , Machado, M. , Yeager, M. , Brooks-Wilson, A. R. , Hartge, P. , Purdue, M. P. & 30 others Birmann, B. M., Vajdic, C. M., Cocco, P., Zhang, Y., Giles, G. G., Zeleniuch-Jacquotte, A., Lawrence, C., Montalvan, R., Burdett, L., Hutchinson, A., Ye, Y., Call, T. G., Shanafelt, T. D., Novak, A. J., Kay, N. E., Liebow, M., Cunningham, J. M., Allmer, C., Hjalgrim, H., Adami, H. O., Melbye, M., Glimelius, B., Chang, E. T., Glenn, M., Curtin, K., Cannon-Albright, L. A., Diver, W. R., Link, B. K., Weiner, G. J. & Conde, L. Mar 9 2016 In : Nature Communications. 7, 10933

Research output: Contribution to journalArticle

leukemias
genome
Genome-Wide Association Study
B-Cell Chronic Lymphocytic Leukemia
loci
3 Citations

Meta-Analysis of Genome-Wide Association Studies with Correlated Individuals: Application to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Sofer, T., Shaffer, J. R., Graff, M., Qi, Q., Stilp, A. M., Gogarten, S. M., North, K. E., Isasi, C. R., Laurie, C. C. & Szpiro, A. A. Sep 1 2016 In : Genetic Epidemiology. 40, 6, p. 492-501 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans
Meta-Analysis
Economic Inflation
Health
36 Citations

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Y. , Day, F. R. , Gustafsson, S. , Buchkovich, M. L. , Na, J. , Bataille, V. , Cousminer, D. L. , Dastani, Z. , Drong, A. W. , Esko, T. , Evans, D. M. , Falchi, M. , Feitosa, M. F. , Ferreira, T. , Hedman, Å. K. , Haring, R. , Hysi, P. G. , Iles, M. M. , Justice, A. E. , Kanoni, S. & 30 others Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T. & Choh, A. C. Feb 1 2016 In : Nature Communications. 7, 10495

Research output: Contribution to journalArticle

Adiposity
fats
loci
Adipose Tissue
Fats
11 Citations

Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk

Yu, B. , Pulit, S. L. , Hwang, S. J. , Brody, J. A. , Amin, N. , Auer, P. L. , Bis, J. C. , Boerwinkle, E. , Burke, G. L. , Chakravarti, A. , Correa, A. , Dreisbach, A. W. , Franco, O. H. , Ehret, G. B. , Franceschini, N. , Hofman, A. , Lin, D. Y. , Metcalf, G. A. , Musani, S. K. , Muzny, D. & 15 others Palmas, W., Raffel, L., Reiner, A., Rice, K., Rotter, J. I., Veeraraghavan, N., Fox, E., Guo, X., North, K. E., Gibbs, R. A., Van Duijn, C. M., Psaty, B. M., Levy, D., Newton-Cheh, C. & Morrison, A. C. Feb 1 2016 In : Circulation: Cardiovascular Genetics. 9, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

Exome
Blood Pressure
Hypertension
Gene Frequency
Meta-Analysis

Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project

Kan, M. , Auer, P. L. , Wang, G. T. , Bucasas, K. L. , Hooker, S. , Rodriguez, A. , Li, B. , Ellis, J. , Cupples, L. A. , Chen, Y. D. I. , Dupuis, J. , Fox, C. S. , Gross, M. D. , Smith, J. D. , Heard-Costa, N. , Meigs, J. B. , Pankow, J. S. , Rotter, J. I. , Siscovick, D. , Wilson, J. G. & 17 others Shendure, J., Jackson, R., Peters, U., Zhong, H., Lin, D., Hsu, L., Franceschini, N., Carlson, C., Abecasis, G., Gabriel, S., Bamshad, M. J., Altshuler, D., Nickerson, D. A., North, K. E., Lange, L. A., Reiner, A. P. & Leal, S. M. Aug 1 2016 In : European Journal of Human Genetics. 24, 8, p. 1181-1187 7 p.

Research output: Contribution to journalArticle

Exome
National Heart, Lung, and Blood Institute (U.S.)
Waist-Hip Ratio
African Americans
I-kappa B Kinase
3 Citations

Testing the role of predicted gene knockouts in human anthropometric trait variation

NHLBI GO Exome Sequence Project, GOT2D, T2D-GENES & GIANT Consortium May 15 2016 In : Human Molecular Genetics. 25, 10, p. 2082-2092 11 p., ddw055

Research output: Contribution to journalArticle

Gene Knockout Techniques
Exome
Body Mass Index
Waist-Hip Ratio
National Heart, Lung, and Blood Institute (U.S.)
2 Citations

The interaction between physical activity and obesity gene variants in association with BMI: Does the obesogenic environment matter?

Graff, M., Richardson, A. S., Young, K. L., Mazul, A. L., Highland, H., North, K. E., Mohlke, K. L., Lange, L. A., Lange, E. M., Harris, K. M. & Gordon-Larsen, P. Nov 1 2016 In : Health and Place. 42, p. 159-165 7 p.

Research output: Contribution to journalArticle

physical activity
obesity
Obesity
Exercise
adolescence
12 Citations

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

Liu, C. T. , Raghavan, S. , Maruthur, N. , Kabagambe, E. K. , Hong, J. , Ng, M. C. Y. , Hivert, M. F. , Lu, Y. , An, P. , Bentley, A. R. , Drolet, A. M. , Gaulton, K. J. , Guo, X. , Armstrong, L. L. , Irvin, M. R. , Li, M. , Lipovich, L. , Rybin, D. V. , Taylor, K. D. , Agyemang, C. & 30 others Palmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J. & Crawford, D. C. Jul 7 2016 In : American journal of human genetics. 99, 1, p. 56-75 20 p.

Research output: Contribution to journalArticle

Meta-Analysis
Fasting
Insulin
Glucose
Type 2 Diabetes Mellitus
4 Citations

Variant discovery and fine mapping of genetic loci associated with blood pressure traits in Hispanics and African Americans

Franceschini, N. , Carty, C. L. , Lu, Y. , Tao, R. , Sung, Y. J. , Manichaikul, A. , Haessler, J. , Fornage, M. , Schwander, K. , Zubair, N. , Bien, S. , Hindorff, L. A. , Guo, X. , Bielinski, S. J. , Ehret, G. , Kaufman, J. D. , Rich, S. S. , Carlson, C. S. , Bottinger, E. P. , North, K. E. & 6 others Rao, D. C., Chakravarti, A., Barrett, P. Q., Loos, R. J. F., Buyske, S. & Kooperberg, C. Oct 1 2016 In : PLoS ONE. 11, 10, e0164132

Research output: Contribution to journalArticle

Hispanic Americans
Genetic Loci
Blood pressure
African Americans
chromosome mapping
2015
15 Citations

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Vijai, J. , Wang, Z. , Berndt, S. I. , Skibola, C. F. , Slager, S. L. , De Sanjose, S. , Melbye, M. , Glimelius, B. , Bracci, P. M. , Conde, L. , Birmann, B. M. , Wang, S. S. , Brooks-Wilson, A. R. , Lan, Q. , De Bakker, P. I. W. , Vermeulen, R. C. H. , Portlock, C. , Ansell, S. M. , Link, B. K. , Riby, J. & 30 others North, K. E., Gu, J., Hjalgrim, H., Cozen, W., Becker, N., Teras, L. R., Spinelli, J. J., Turner, J., Zhang, Y., Purdue, M. P., Giles, G. G., Kelly, R. S., Zeleniuch-Jacquotte, A., Ennas, M. G., Monnereau, A., Bertrand, K. A., Albanes, D., Lightfoot, T., Yeager, M., Chung, C. C., Burdett, L., Hutchinson, A., Lawrence, C., Montalvan, R., Liang, L., Huang, J., Ma, B., Villano, D. J., Maria, A. & Corines, M. Jan 8 2015 In : Nature Communications. 6, 6751

Research output: Contribution to journalArticle

HLA-B Antigens
genome
Genome-Wide Association Study
loci
Lymphoma
3 Citations

Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling

Tao, R., Zeng, D., Franceschini, N., North, K. E., Boerwinkle, E. & Lin, D. Y. Apr 3 2015 In : Journal of the American Statistical Association. 110, 510, p. 560-572 13 p.

Research output: Contribution to journalArticle

Linear regression
Sequencing
Dependent
Simultaneous Inference
Genetic Association
8 Citations

Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians

Tsai, C. W., North, K. E., Tin, A., Haack, K., Franceschini, N., Voruganti, V. S., Laston, S., Zhang, Y., Best, L. G., MacCluer, J. W., Beaty, T. H., Navas-Acien, A., Kao, W. H. L. & Howard, B. V. Feb 1 2015 In : Journal of Clinical Endocrinology and Metabolism. 100, 2, p. E345-E349

Research output: Contribution to journalArticle

Proprotein Convertases
Subtilisin
North American Indians
LDL Cholesterol
Plasmas
14 Citations

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: A meta-analysis of 50,345 Caucasians

Fretts, A. M. , Follis, J. L. , Nettleton, J. A. , Lemaitre, R. N. , Ngwa, J. S. , Wojczynski, M. K. , Kalafati, I. P. , Varga, T. V. , Frazier-Wood, A. C. , Houston, D. K. , Lahti, J. , Ericson, U. , Van Den Hooven, E. H. , Mikkilä, V. , Kiefte-De Jong, J. C. , Mozaffarian, D. , Rice, K. , Renström, F. , North, K. E. , McKeown, N. M. & 30 others Feitosa, M. F., Kanoni, S., Smith, C. E., Garcia, M. E., Tiainen, A. M., Sonestedt, E., Manichaikul, A., Van Rooij, F. J. A., Dimitriou, M., Raitakari, O., Pankow, J. S., Djoussé, L., Province, M. A., Hu, F. B., Lai, C. Q., Keller, M. F., Perälä, M. M., Rotter, J. I., Hofman, A., Graff, M., Kähönen, M., Mukamal, K., Johansson, I., Ordovas, J. M., Liu, Y., Männistö, S., Uitterlinden, A. G., Deloukas, P., Seppälä, I. & Psaty, B. M. Nov 1 2015 In : American Journal of Clinical Nutrition. 102, 5, p. 1266-1278 13 p.

Research output: Contribution to journalArticle

Meat
Meta-Analysis
Fasting
Insulin
Glucose
42 Citations

Directional dominance on stature and cognition in diverse human populations

The Bio Bank Japan Project Jul 23 2015 In : Nature. 523, 7561, p. 459-462 4 p.

Research output: Contribution to journalArticle

Cognition
Genome
Population
Aptitude
Inbreeding
27 Citations

Gene × dietary pattern interactions in obesity: Analysis of up to 68 317 adults of European ancestry

Nettleton, J. A. , Follis, J. L. , Ngwa, J. S. , Smith, C. E. , Ahmad, S. , Tanaka, T. , Wojczynski, M. K. , Voortman, T. , Lemaitre, R. N. , Kristiansson, K. , Nuotio, M. L. , Houston, D. K. , Perälä, M. M. , Qi, Q. , Sonestedt, E. , Manichaikul, A. , Kanoni, S. , Ganna, A. , Mikkilä, V. , North, K. E. & 30 others Siscovick, D. S., Harald, K., Mckeown, N. M., Johansson, I., Rissanen, H., Liu, Y., Lahti, J., Hu, F. B., Bandinelli, S., Rukh, G., Rich, S., Booij, L., Dmitriou, M., Ax, E., Raitakari, O., Mukamal, K., Männistö, S., Hallmans, G., Jula, A., Ericson, U., Jacobs, D. R., Frank, F. J., Deloukas, P., Sjögren, P., Kähönen, M., Djousse, L., Perola, M., Barroso, I., Hofman, A. & Stirrups, K. Apr 28 2015 In : Human molecular genetics. 24, 16, p. 4728-4738 11 p.

Research output: Contribution to journalArticle

Body Mass Index
Waist-Hip Ratio
Obesity
Genes
Diet
4 Citations

Genetic determinants of pelvic organ prolapse among African American and Hispanic women in the Women's Health Initiative

Giri, A., Wu, J. M., Ward, R. M., Hartmann, K. E., Park, A. J., North, K. E., Graff, M., Wallace, R. B., Bareh, G., Qi, L., O'Sullivan, M. J., Reiner, A. P., Edwards, T. L. & Edwards, D. R. V. Nov 6 2015 In : PLoS ONE. 10, 11, e0141647

Research output: Contribution to journalArticle

women's health
Pelvic Organ Prolapse
Women's Health
African Americans
Hispanic Americans
4 Citations

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration

Lanktree, M. B., Elbers, C. C., Li, Y., Zhang, G., Duan, Q., Karczewski, K. J., Guo, Y., Tragante, V., North, K. E., Cushman, M., Asselbergs, F. W., Wilson, J. G., Lange, L. A., Drenos, F., Reiner, A. P., Barnes, M. R. & Keating, B. J. Sep 1 2015 In : Journal of Lipid Research. 56, 9, p. 1781-1786 6 p.

Research output: Contribution to journalArticle

African Americans
Meta-Analysis
Lipids
Genes
Single Nucleotide Polymorphism
802 Citations

Genetic studies of body mass index yield new insights for obesity biology

The LifeLines Cohort Study, The ADIPOGen Consortium, The AGEN-BMI Working Group, The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The GLGC, The ICBP, The MAGIC Investigators, The MuTHER Consortium, The MIGen Consortium, The PAGE Consortium, The ReproGen Consortium, The GENIE Consortium & The International Endogene Consortium Feb 12 2015 In : Nature. 518, 7538, p. 197-206 10 p.

Research output: Contribution to journalArticle

Body Mass Index
Obesity
Adipogenesis
Genome-Wide Association Study
Adiposity
38 Citations

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

Cornelis, M. C. , Byrne, E. M. , Esko, T. , Nalls, M. A. , Ganna, A. , Paynter, N. , Monda, K. L. , Amin, N. , Fischer, K. , Renstrom, F. , Ngwa, J. S. , Huikari, V. , Cavadino, A. , Nolte, I. M. , Teumer, A. , Yu, K. , Marques-Vidal, P. , Rawal, R. , Manichaikul, A. , Wojczynski, M. K. & 30 others Vink, J. M., Zhao, J. H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R. N., Eriksson, J., Musani, S. K., Tanaka, T., Geller, F., Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M. E., Ho, W. K., Wright, M. J., Rose, L. M., Magnusson, P. K. E., Pedersen, N. L., Couper, D., Oostra, B. A., Hofman, A., Ikram, M. A., Tiemeier, H. W., Uitterlinden, A. G., Van Rooij, F. J. A., Barroso, I., Johansson, I. & Xue, L. Jan 1 2015 In : Molecular Psychiatry. 20, 5, p. 647-656 10 p.

Research output: Contribution to journalComment/debate

Coffee
Meta-Analysis
Genome
Single Nucleotide Polymorphism
Caffeine
22 Citations

Identification of obesity and cardiovascular risk in ethnically and racially diverse populations: A scientific statement from the American Heart Association

Rao, G., Powell-Wiley, T. M., Ancheta, I., Hairston, K., Kirley, K., Lear, S. A., North, K. E., Palaniappan, L. & Rosal, M. C. Aug 4 2015 In : Circulation. 132, 5, p. 457-472 16 p.

Research output: Contribution to journalArticle

Waist-Hip Ratio
Asian Americans
Waist Circumference
Hispanic Americans
Body Mass Index
3 Citations
Longitudinal Studies
Body Mass Index
Obesity
Smoking
Health
3 Citations

Lack of association of apolipoprotein E (Apo E) polymorphism with the prevalence of metabolic syndrome: The National Heart, Lung and Blood Institute Family Heart Study

Lai, L. Y. H., Petrone, A. B., Pankow, J. S., Arnett, D. K., North, K. E., Ellison, R. C., Hunt, S. C., Rosenzweig, J. L. & Djoussé, L. Sep 1 2015 In : Diabetes/Metabolism Research and Reviews. 31, 6, p. 582-587 6 p.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Apolipoproteins E
Genotype
Odds Ratio
Confidence Intervals
4 Citations

Linkage analysis of urine arsenic species patterns in the Strong Heart Family Study

Gribble, M. O., Voruganti, V. S., Cole, S. A., Haack, K., Balakrishnan, P., Laston, S. L., Tellez-Plaza, M., Francesconi, K. A., Goessler, W., Umans, J. G., Thomas, D. C., Gilliland, F., North, K. E., Franceschini, N. & Navas-Acien, A. Jan 1 2015 In : Toxicological Sciences. 148, 1, p. 89-100 12 p., kfv164

Research output: Contribution to journalArticle

Arsenic
Urine
Genes
Quantitative Trait Loci
Dynamic mechanical analysis
113 Citations

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V. , Asselbergs, F. W. , Palmer, T. M. , Drenos, F. , Lanktree, M. B. , Nelson, C. P. , Dale, C. E. , Padmanabhan, S. , Finan, C. , Swerdlow, D. I. , Tragante, V. , Van Iperen, E. P. A. , Sivapalaratnam, S. , Shah, S. , Elbers, C. C. , Shah, T. , Engmann, J. , Giambartolomei, C. , White, J. , Zabaneh, D. & 30 others Sofat, R., McLachlan, S., Doevendans, P. A., Balmforth, A. J., Hall, A. S., North, K. E., Almoguera, B., Hoogeveen, R. C., Cushman, M., Fornage, M., Patel, S. R., Redline, S., Siscovick, D. S., Tsai, M. Y., Karczewski, K. J., Hofker, M. H., Verschuren, W. M., Bots, M. L., Van Der Schouw, Y. T., Melander, O., Dominiczak, A. F., Morris, R., Ben-Shlomo, Y., Price, J., Kumari, M., Baumert, J., Peters, A., Thorand, B., Koenig, W. & Lange, L. A. Jan 1 2015 In : European heart journal. 36, 9, p. 539-550 12 p.

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Coronary Disease
HDL Cholesterol
Lipids
16 Citations

Molecular mechanisms underlying variations in lung function: A systems genetics analysis

Obeidat, M. , Hao, K. , Bossé, Y. , Nickle, D. C. , Nie, Y. , Postma, D. S. , Laviolette, M. , Sandford, A. J. , Daley, D. D. , Hogg, J. C. , Elliott, W. M. , Fishbane, N. , Timens, W. , Hysi, P. G. , Kaprio, J. , Wilson, J. F. , Hui, J. , Rawal, R. , Schulz, H. , Stubbe, B. & 26 others Hayward, C., Polasek, O., Järvelin, M. R., Zhao, J. H., Jarvis, D., Kähönen, M., Franceschini, N., North, K. E., Loth, D. W., Brusselle, G. G., Smith, A. V., Gudnason, V., Bartz, T. M., Wilk, J. B., O'Connor, G. T., Cassano, P. A., Tang, W., Wain, L. V., Artigas, M. S., Gharib, S. A., Strachan, D. P., Sin, D. D., Tobin, M. D., London, S. J., Hall, I. P. & Paré, P. D. Jan 1 2015 In : The Lancet Respiratory Medicine. 3, 10, p. 782-795 14 p.

Research output: Contribution to journalArticle

Lung
Chronic Obstructive Pulmonary Disease
Quantitative Trait Loci
Genome-Wide Association Study
Genes
288 Citations

New genetic loci link adipose and insulin biology to body fat distribution

The LifeLines Cohort Study, The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The GEFOS Consortium, The GENIE Consortium, The GLGC, The ICBP, The International Endogene Consortium, The MAGIC Investigators, The MuTHER Consortium, The PAGE Consortium & The ReproGen Consortium Feb 12 2015 In : Nature. 518, 7538, p. 187-196 10 p.

Research output: Contribution to journalArticle

Body Fat Distribution
Genetic Loci
Waist-Hip Ratio
Waist Circumference
Hip
35 Citations

Population genetic differentiation of height and body mass index across Europe

Robinson, M. R. , Hemani, G. , Medina-Gomez, C. , Mezzavilla, M. , Esko, T. , Shakhbazov, K. , Powell, J. E. , Vinkhuyzen, A. , Berndt, S. I. , Gustafsson, S. , Justice, A. E. , Kahali, B. , Locke, A. E. , Pers, T. H. , Vedantam, S. , Wood, A. R. , Van Rheenen, W. , Andreassen, O. A. , Gasparini, P. , Metspalu, A. & 23 others Van Den Berg, L. H., Veldink, J. H., Rivadeneira, F., Werge, T. M., Abecasis, G. R., Boomsma, D. I., Chasman, D. I., De Geus, E. J. C., Frayling, T. M., Hirschhorn, J. N., Hottenga, J. J., Ingelsson, E., Loos, R. J. F., Magnusson, P. K. E., Martin, N. G., Montgomery, G. W., North, K. E., Pedersen, N. L., Spector, T. D., Speliotes, E. K., Goddard, M. E., Yang, J. & Visscher, P. M. Jan 1 2015 In : Nature Genetics. 47, 11, p. 1357-1361 5 p.

Research output: Contribution to journalArticle

Population Genetics
Body Mass Index
Phenotype
Population
45 Citations

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

CHARGE consortium., DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium & MAGIC Consortium Jan 1 2015 In : PLoS genetics. 11, 10, p. 1-42 42 p., e1005378

Research output: Contribution to journalArticle

body shape
Body Size
anthropometric measurements
body size
genome
10 Citations

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

Shungin, D. , Cornelis, M. C. , Divaris, K. , Holtfreter, B. , Shaffer, J. R. , Yu, Y. H. , Barros, S. P. , Beck, J. D. , Biffar, R. , Boerwinkle, E. A. , Crout, R. J. , Ganna, A. , Hallmans, G. , Hindy, G. , Hu, F. B. , Kraft, P. , McNeil, D. W. , Melander, O. , Moss, K. L. , North, K. E. & 21 others Orho-Melander, M., Pedersen, N. L., Ridker, P. M., Rimm, E. B., Rose, L. M., Rukh, G., Teumer, A., Weyant, R. J., Chasman, D. I., Joshipura, K., Kocher, T., Magnusson, P. K. E., Marazita, M. L., Nilsson, P., Offenbacher, S., Smith, G. D., Lundberg, P., Palmer, T. M., Timpson, N. J., Johansson, I. & Franks, P. W. May 27 2015 In : International journal of epidemiology. 44, 2, p. 638-650 13 p., dyv075

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Periodontitis
Adiposity
Life Style
Tooth
2014
4 Citations

ADAM19 and HTR4 variants and pulmonary function cohorts for heart and aging research in genomic epidemiology (charge) consortium targeted sequencing study

London, S. J., Gao, W., Gharib, S. A., Hancock, D. B., Wilk, J. B., House, J. S., Gibbs, R. A., Muzny, D. M., Lumley, T., Franceschini, N., North, K. E., Psaty, B. M., Kovar, C. L., Coresh, J., Zhou, Y., Heckbert, S. R., Brody, J. A. & Morrison, A. C. 2014 In : Circulation: Cardiovascular Genetics. 7, 3, p. 350-358 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Forced Expiratory Volume
Vital Capacity
Epidemiology
Lung