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2017
4 Citations

Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers

Asher, G. N., Xie, Y., Moaddel, R., Sanghvi, M., Dossou, K. S. S., Kashuba, A. D. M., Sandler, R. S. & Hawke, R. L. Jan 1 2017 In : Journal of Clinical Pharmacology. 57, 2, p. 185-193 9 p.

Research output: Contribution to journalArticle

Curcumin
Cross-Over Studies
Healthy Volunteers
Pharmacokinetics
Phosphatidylcholines
2016
6 Citations

Analysis of Antiretrovirals in Single Hair Strands for Evaluation of Drug Adherence with Infrared-Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging

Rosen, E. P., Thompson, C. G., Bokhart, M. T., Prince, H. M. A., Sykes, C., Muddiman, D. C. & Kashuba, A. D. M. Jan 19 2016 In : Analytical Chemistry. 88, 2, p. 1336-1344 9 p.

Research output: Contribution to journalArticle

Electrospray ionization
Mass spectrometry
Desorption
Infrared radiation
Imaging techniques
1 Citations

Antiretroviral activity and safety of once-daily etravirine in treatment-naive HIV-infected adults: 48-week results

Floris-Moore, M. A., Mollan, K., Wilkin, A. M., Johnson, M. A., Kashuba, A. D. M., Wohl, D. A., Patterson, K. B., Francis, O., Kronk, C. & Eron, J. J. 2016 In : Antiviral Therapy. 21, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

etravirine
HIV
Safety
HIV-1
Tenofovir
1 Citations

A Pharmacokinetic and Pharmacodynamic Study of Maraviroc as Acute Graft-versus-Host Disease Prophylaxis in Pediatric Allogeneic Stem Cell Transplant Recipients with Nonmalignant Diagnoses

Khandelwal, P., Fukuda, T., Mizuno, K., Teusink-Cross, A., Mehta, P. A., Marsh, R. A., Kashuba, A. D. M., Vinks, A. A. & Davies, S. M. Oct 1 2016 In : Biology of Blood and Marrow Transplantation. 22, 10, p. 1829-1835 7 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Stem Cells
Pharmacokinetics
Pediatrics
Transplants
47 Citations
Tenofovir
Mucous Membrane
HIV
Pharmacology
Nucleotides
3 Citations

Cervicovaginal and rectal fluid as a surrogate marker of antiretroviral tissue concentration: Implications for clinical trial design

Cottrell, M. L., Prince, H. M. A., Allmon, A., Mollan, K. R., Hudgens, M. G., Sykes, C., White, N., Malone, S., Dellon, E. S., Madanick, R. D., Shaheen, N. J., Patterson, K. B. & Kashuba, A. D. M. Aug 15 2016 In : Journal of Acquired Immune Deficiency Syndromes. 72, 5, p. 498-506 9 p.

Research output: Contribution to journalArticle

Biomarkers
Clinical Trials
Tenofovir
Lower Gastrointestinal Tract
Pharmaceutical Preparations
24 Citations

Dose Frequency Ranging Pharmacokinetic Study of Tenofovir-Emtricitabine after Directly Observed Dosing in Healthy Volunteers to Establish Adherence Benchmarks (HPTN 066)

Hendrix, C. W. , Andrade, A. , Bumpus, N. N. , Kashuba, A. D. , Marzinke, M. A. , Moore, A. , Anderson, P. L. , Bushman, L. R. , Fuchs, E. J. , Wiggins, I. , Radebaugh, C. , Prince, H. A. , Bakshi, R. P. , Wang, R. , Richardson, P. , Shieh, E. , McKinstry, L. , Li, X. , Donnell, D. , Elharrar, V. & 2 others Mayer, K. H. & Patterson, K. B. Jan 1 2016 In : AIDS Research and Human Retroviruses. 32, 1, p. 32-43 12 p.

Research output: Contribution to journalArticle

Tenofovir
Benchmarking
Healthy Volunteers
Pharmacokinetics
Tablets
17 Citations

Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

Serrano-Villar, S., Sainz, T., Ma, Z. M., Utay, N. S., Wook-Chun, T., Mann, S., Kashuba, A. D., Siewe, B., Albanese, A., Troia-Cancio, P., Sinclair, E., Somasunderam, A., Yotter, T., Deeks, S. G., Landay, A., Pollard, R. B., Miller, C. J., Moreno, S. & Asmuth, D. M. Jan 1 2016 In : PLoS Pathogens. 12, 1, e1005381

Research output: Contribution to journalArticle

Integrase Inhibitors
Mucosal Immunity
HIV
T-Lymphocytes
T-Lymphocyte Subsets
4 Citations

HIV-1-RNA decay and dolutegravir concentrations in semen of patients starting a first antiretroviral regimen

Imaz, A., Martinez-Picado, J., Niubó, J., Kashuba, A. D. M., Ferrer, E., Ouchi, D., Sykes, C., Rozas, N., Acerete, L., Curto, J., Vila, A. & Podzamczer, D. Nov 15 2016 In : Journal of Infectious Diseases. 214, 10, p. 1512-1519 8 p.

Research output: Contribution to journalArticle

RNA Stability
Semen
HIV-1
RNA
dolutegravir
3 Citations

Mucosal tissue pharmacokinetics of the integrase inhibitor raltegravir in a humanized mouse model: Implications for HIV pre-exposure prophylaxis

Veselinovic, M., Yang, K. H., Sykes, C., Remling-Mulder, L., Kashuba, A. D. M. & Akkina, R. Feb 1 2016 In : Virology. 489, p. 173-178 6 p.

Research output: Contribution to journalArticle

Integrase Inhibitors
Mucous Membrane
Pharmacokinetics
HIV
Pharmaceutical Preparations
Virus Diseases
Coinfection
Hepacivirus
Antiviral Agents
HIV
1 Citations

Plasma and Intracellular Concentrations in HIV-Infected Patients Requiring Hemodialysis Dosed with Tenofovir Disoproxil Fumarate and Emtricitabine

Slaven, J. E., Decker, B. S., Kashuba, A. D. M., Atta, M. G., Wyatt, C. M. & Gupta, S. K. Sep 1 2016 In : Journal of Acquired Immune Deficiency Syndromes. 73, 1, p. e8-e10

Research output: Contribution to journalLetter

2 Citations

Saquinavir Loaded Acetalated Dextran Microconfetti – a Long Acting Protease Inhibitor Injectable

Collier, M. A., Gallovic, M. D., Bachelder, E. M., Sykes, C. D., Kashuba, A. & Ainslie, K. M. Aug 1 2016 In : Pharmaceutical Research. 33, 8, p. 1998-2009 12 p.

Research output: Contribution to journalArticle

Saquinavir
Dextrans
Protease Inhibitors
Injections
Pharmaceutical Preparations

S-warfarin limited sampling models to estimate area under the concentration versus time curve for cytochrome P450 2C9 baseline activity and after induction

Chang, A. T., Bertino, J. S., Nafziger, A. N., Kashuba, A. D. M., Turpault, S., Lewis, L. D. & Ma, J. D. Jan 1 2016 In : Therapeutic Drug Monitoring. 38, 3, p. 383-387 5 p.

Research output: Contribution to journalArticle

Warfarin
Cytochrome P-450 Enzyme System
Area Under Curve
Neoplasms
Lopinavir
9 Citations

The differential short- and long-term effects of HIV-1 latency-reversing agents on T cell function

Clutton, G., Xu, Y., Baldoni, P. L., Mollan, K. R., Kirchherr, J., Newhard, W., Cox, K., Kuruc, J. D., Kashuba, A., Barnard, R., Archin, N., Gay, C. L., Hudgens, M. G., Margolis, D. M. & Goonetilleke, N. Aug 2 2016 In : Scientific Reports. 6, 30749

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
Histone Deacetylase Inhibitors
Protein Kinase C
CD8 Antigens
2015
17 Citations

Accuracy of Self-Report and Pill-Count Measures of Adherence in the FEM-PrEP Clinical Trial: Implications for Future HIV-Prevention Trials

Agot, K., Taylor, D., Corneli, A. L., Wang, M., Ambia, J., Kashuba, A. D. M., Parker, C., Lemons, A., Malahleha, M., Lombaard, J. & Van Damme, L. May 1 2015 In : AIDS and Behavior. 19, 5, p. 743-751 9 p.

Research output: Contribution to journalArticle

Tenofovir
Self Report
Clinical Trials
HIV
Pharmaceutical Preparations
52 Citations

Bottlenecks in HIV-1 transmission: Insights from the study of founder viruses

Joseph, S. B., Swanstrom, R., Kashuba, A. D. M. & Cohen, M. S. Jan 1 2015 In : Nature Reviews Microbiology. 13, 7, p. 414-425 12 p.

Research output: Contribution to journalReview article

HIV-1
Viruses
HIV Infections
Phenotype
9 Citations

Co-localized confocal Raman spectroscopy and optical coherence tomography (CRS-OCT) for depth-resolved analyte detection in tissue

Maher, J. R., Chuchuen, O., Henderson, M. H., Kim, S., Rinehart, M. T., Kashuba, A. D. M., Wax, A. & Katz, D. F. May 8 2015 In : Biomedical Optics Express. 6, 6, p. 2022-2035 14 p.

Research output: Contribution to journalArticle

Raman Spectrum Analysis
Optical Coherence Tomography
Tenofovir
Raman spectroscopy
tomography

Combined raman spectroscopy and optical coherence tomography for measuring analytes in targeted tissues

Maher, J. R., Chuchuen, O., Kashuba, A. D. M., Katz, D. F. & Wax, A. Apr 6 2015 Optical Molecular Probes, Imaging and Drug Delivery, OMP 2015. OSA - The Optical Society

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Raman Spectrum Analysis
Optical tomography
Optical Coherence Tomography
Anti-Infective Agents
Raman spectroscopy
11 Citations

Effect of cytomegalovirus infection on breastfeeding transmission of HIV and on the health of infants born to HIV-infected mothers

Chang, T. S. , Wiener, J. , Dollard, S. C. , Amin, M. M. , Ellington, S. , Chasela, C. , Kayira, D. , Tegha, G. , Kamwendo, D. , Jamieson, D. J. , Van Der Horst, C. , Kourtis, A. P. , Adair, L. , Ahmed, Y. , Ait-Khaled, M. , Albrecht, S. , Bangdiwala, S. , Bayer, R. , Bentley, M. , Bramson, B. & 30 others Bobrow, E., Boyle, N., Butera, S., Chavula, C., Chimerang'ambe, J., Chigwenembe, M., Chikasema, M., Chikhungu, N., Chilongozi, D., Chiudzu, G., Chome, L., Cole, A., Corbett, A., Corneli, A., Dow, A., Duerr, A., Eliya, H., Eron, J., Farr, S., Ferguson, Y. O., Fiscus, S., Flax, V., Hoffman, I., Hosseinipour, M., Hudgens, M., Kamthunzi, P., Kanyama, C., Kashuba, A., Martinson, F. & Moses, A. Apr 24 2015 In : AIDS. 29, 7, p. 831-836 6 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Breast Feeding
Mothers
HIV
Cytomegalovirus
2 Citations

Effect of HIV infection and menopause status on raltegravir pharmacokinetics in the blood and genital tract

Cottrell, M. L., Patterson, K. B., Prince, H. M. A., Jones, A., White, N., Wang, R. & Kashuba, A. D. M. 2015 In : Antiviral Therapy. 20, 8, p. 795-803 9 p.

Research output: Contribution to journalArticle

Menopause
HIV Infections
Pharmacokinetics
HIV
Area Under Curve
28 Citations

Genital Tenofovir Concentrations Correlate with Protection Against HIV Infection in the CAPRISA 004 Trial: Importance of Adherence for Microbicide Effectiveness

Kashuba, A. D. M., Gengiah, T. N., Werner, L., Yang, K. H., White, N. R., Karim, Q. A. & Abdool Karim, S. S. Jul 1 2015 In : Journal of Acquired Immune Deficiency Syndromes. 69, 3, p. 264-269 6 p.

Research output: Contribution to journalArticle

Tenofovir
Anti-Infective Agents
HIV Infections
HIV
Gels
1 Citations
HIV
Therapeutic Irrigation
Endometrium
Biomarkers
RNA
4 Citations

Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: In vitro and in vivo correlation

Sabo, J. P., Kort, J., Ballow, C., Kashuba, A. D. M., Haschke, M., Battegay, M., Girlich, B., Ting, N., Lang, B., Zhang, W., Cooper, C., O'Brien, D., Seibert, E., Chan, T. S., Tweedie, D. & Li, Y. Jan 1 2015 In : Journal of Clinical Pharmacology. 55, 4, p. 467-477 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Protease Inhibitors
Hepacivirus
Cytochrome P-450 Enzyme System
Area Under Curve
4 Citations

Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation

Peterson, C. W., Haworth, K. G., Polacino, P., Huang, M. L., Sykes, C., Obenza, W. M., Repetto, A. C., Kashuba, A., Bumgarner, R., DeRosa, S. C., Woolfrey, A. E., Jerome, K. R., Mullins, J. I., Hu, S. L. & Kiem, H. P. Aug 24 2015 In : AIDS. 29, 13, p. 1597-1606 10 p.

Research output: Contribution to journalArticle

Macaca
Bone Marrow Transplantation
Mutation
Hematopoietic Stem Cell Transplantation
Viremia
2 Citations

Low frequency of drug-resistant variants selected by long-acting rilpivirine in macaques infected with simian immunodeficiency virus containing HIV-1 reverse transcriptase

Melody, K., McBeth, S., Kline, C., Kashuba, A. D. M., Mellors, J. W. & Ambrose, Z. Dec 1 2015 In : Antimicrobial Agents and Chemotherapy. 59, 12, p. 7762-7770 9 p.

Research output: Contribution to journalArticle

Rilpivirine
Simian Immunodeficiency Virus
Macaca
HIV-1
RNA-Directed DNA Polymerase
19 Citations

Mass spectrometry imaging reveals heterogeneous efavirenz distribution within putative HIV reservoirs

Thompson, C. G., Bokhart, M. T., Sykes, C., Adamson, L., Fedoriw, Y., Luciw, P. A., Muddiman, D. C., Kashuba, A. D. M. & Rosen, E. P. May 1 2015 In : Antimicrobial Agents and Chemotherapy. 59, 5, p. 2944-2948 5 p.

Research output: Contribution to journalArticle

efavirenz
Mass Spectrometry
HIV
Macaca
Pharmaceutical Preparations
10 Citations

Models for predicting effective HIV chemoprevention in women

Nicol, M. R., Emerson, C. W., Prince, H. M. A., Nelson, J. A. E., Fedoriw, Y., Sykes, C., Geller, E. J., Patterson, K. B., Cohen, M. S. & Kashuba, A. D. M. Apr 1 2015 In : Journal of Acquired Immune Deficiency Syndromes. 68, 4, p. 369-376 8 p.

Research output: Contribution to journalArticle

Tenofovir
Chemoprevention
HIV
HIV Infections
Protective Agents
1 Citations

Pharmacokinetic modeling of lamivudine and zidovudine triphosphates predicts differential pharmacokinetics in seminal mononuclear cells and peripheral blood mononuclear cells

Dumond, J. B., Yang, K. H., Kendrick, R., Reddy, Y. S., Kashuba, A. D. M., Troiani, L., Bridges, A. S., Fiscus, S. A., Forrest, A. & Cohen, M. S. Oct 1 2015 In : Antimicrobial Agents and Chemotherapy. 59, 10, p. 6395-6401 7 p.

Research output: Contribution to journalArticle

Blood Cells
Pharmacokinetics
Zidovudine
Semen
Lamivudine
13 Citations

Pharmacokinetics of antiretrovirals in mucosal tissue

Cottrell, M. L., Srinivas, N. & Kashuba, A. D. M. Jan 1 2015 In : Expert Opinion on Drug Metabolism and Toxicology. 11, 6, p. 893-905 13 p.

Research output: Contribution to journalReview article

Pharmacokinetics
Lower Gastrointestinal Tract
Mucous Membrane
HIV
Pharmaceutical Preparations
4 Citations
Micronutrients
Highly Active Antiretroviral Therapy
HIV
Lipids
Food
5 Citations

Proof-of-principle for immune control of global HIV-1 reactivation in vivo

Smith, N. M. G., Mlcochova, P., Watters, S. A., Aasa-Chapman, M. M. I., Rabin, N., Moore, S., Edwards, S. G., Garson, J. A., Grant, P. R., Ferns, R. B., Kashuba, A., Mayor, N. P., Schellekens, J., Marsh, S. G. E., McMichael, A. J., Perelson, A. S., Pillay, D., Goonetilleke, N. & Gupta, R. K. Jul 1 2015 In : Clinical Infectious Diseases. 61, 1, p. 120-128 9 p.

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
Vaccines
Staining and Labeling
Viruses

Significant decreases in both total and unbound lopinavir and amprenavir exposures during coadministration: ACTG protocol A5143/A5147s results

Dumond, J. B., Rigdon, J., Mollan, K., Tierney, C., Kashuba, A. D. M., Aweeka, F. & Collier, A. C. Jan 1 2015 In : Journal of Acquired Immune Deficiency Syndromes. 70, 5, p. 510-514 5 p.

Research output: Contribution to journalArticle

Lopinavir
Hepatitis C
Drug Interactions
Pharmaceutical Preparations
Pharmacokinetics
6 Citations

Sino-implant (II)® continuation and effect of concomitant tenofovir disoproxil fumarate-emtricitabine use on plasma levonorgestrel concentrations among women in Bondo, Kenya

Todd, C. S. , Deese, J. , Wang, M. , Hubacher, D. , Steiner, M. J. , Otunga, S. , Van Damme, L. , Abele, R. , Adagi, L. , Agingu, W. , Agot, K. , Ahmed, K. , Ambia, J. , Andreasen, A. , Asewe, J. , De Baetselier, I. , Bonyo, T. , Cates, W. , Chiduo, S. , Chilwane, M. C. & 70 others Corneli, A., Crucitti, T., Defechereux, P., Dorflinger, L., Fransen, K., Gaddiel, J., Grant, R., Headley, J., Kapiga, S., Kashuba, A., Kiernan, H., Kirkendale, S., Kiyanga, P., Lalbahadur, T., Lanham, M., Lemons, A., Liegler, T., Lombaard, J., Ma, Y. R., Maboa, R. M., Makanda, M., Makatu, S. E., Mak'Oketch, P., Malahleha, M., Malone, S., Mandala, J., Manongi, R., Masaki, M., Mastro, T., Mawere, F., McKenna, K., Mlay, A., Mohale, L. B., Monedi, M. C., Mueller, M., Mullins, S., Naicker, S., Nanda, K., Ndyetabura, T., Ogola, D., Ogola, R. B., Omondi, J., Omullo, P., Omungo, Z., Ogada, T., Ollotu, I., Onyango, J., Onuonga, E., Owino, F., Parker, C., Perry, B., Ratlhagana, M. J. M., Rammutla, E., Reblin, I., Sam, N., Saylor, L., Segoe, T., Siguntu, P., Skhosana, J. S., Taylor, D., Temu, L., Thole, T. T., Thulare, N. G., Troxler, A., Chetty-Tulsee, S., Veena, V., Venkatasubramanian, L., Wassonga, L., White, N. & Wong, C. Jan 1 2015 In : Contraception. 91, 3, p. 248-252 5 p.

Research output: Contribution to journalArticle

Tenofovir
Levonorgestrel
Kenya
Contraception
Placebos
31 Citations

Tenofovir gel for the prevention of herpes simplex virus type 2 infection

Karim, S. S. A., Karim, Q. A., Kharsany, A. B. M., Baxter, C., Grobler, A. C., Werner, L., Kashuba, A., Mansoor, L. E., Samsunder, N., Mindel, A. & Gengiah, T. N. Aug 6 2015 In : New England Journal of Medicine. 373, 6, p. 530-539 10 p.

Research output: Contribution to journalArticle

Tenofovir
Human Herpesvirus 2
Virus Diseases
Gels
Confidence Intervals
2014
4 Citations

Adherence to extended postpartum antiretrovirals is associated with decreased breast milk HIV-1 transmission

Davis, N. L. , Miller, W. C. , Hudgens, M. G. , Chasela, C. S. , Sichali, D. , Kayira, D. , Nelson, J. A. E. , Stringer, J. S. A. , Ellington, S. R. , Kourtis, A. P. , Jamieson, D. J. , Van Der Horst, C. , Adair, L. , Ahmed, Y. , Ait-Khaled, M. , Albrecht, S. , Bangdiwala, S. , Bayer, R. , Bentley, M. , Bramson, B. & 30 others Bobrow, E., Boyle, N., Butera, S., Chavula, C., Chimerang'ambe, J., Chigwenembe, M., Chikasema, M., Chikhungu, N., Chilongozi, D., Chiudzu, G., Chome, L., Cole, A., Corbett, A., Corneli, A., Dow, A., Duerr, A., Eliya, H., Eron, J., Farr, S., Ferguson, Y. O., Fiscus, S., Flax, V., Fokar, A., Hoffman, I., Hosseinipour, M., Kamthunzi, P., Kanyama, C., Kashuba, A., Martinson, F. & Moses, A. Jan 1 2014 In : AIDS. 28, 18, p. 2739-2749 11 p.

Research output: Contribution to journalArticle

Human Milk
Postpartum Period
HIV-1
Mothers
Breast Feeding
17 Citations

A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate

Yang, K. H., Hendrix, C., Bumpus, N., Elliott, J., Tanner, K., Mauck, C., Cranston, R., McGowan, I., Richardson-Harman, N., Anton, P. A. & Kashuba, A. D. M. Oct 28 2014 In : PLoS ONE. 9, 10, e106196

Research output: Contribution to journalArticle

Tenofovir
Pharmacokinetics
pharmacokinetics
mouth
Gels
20 Citations

Antiretroviral pharmacokinetics in mothers and breastfeeding infants from 6 to 24 weeks postpartum: Results of the ban study

Corbett, A. H., Kayira, D., White, N. R., Davis, N. L., Kourtis, A. P., Chasela, C., Martinson, F., Phiri, G., Musisi, B., Kamwendo, D., Hudgens, M. G., Hosseinipour, M. C., Nelson, J. A. E., Ellington, S. R., Jamieson, D. J., Van Horst, C. D., Kashuba, A. & BAN Study Team 2014 In : Antiviral Therapy. 19, 6, p. 587-595 9 p.

Research output: Contribution to journalArticle

Breast Feeding
Human Milk
Postpartum Period
Lamivudine
Pharmacokinetics
Bupropion
Human Activities
Genotype
Liver
Pharmaceutical Preparations
13 Citations

Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study

Richardson-Harman, N., Hendrix, C. W., Bumpus, N. N., Mauck, C., Cranston, R. D., Yang, K., Elliott, J., Tanner, K., McGowan, I., Kashuba, A. & Anton, P. A. Oct 28 2014 In : PLoS ONE. 9, 10, e111507

Research output: Contribution to journalArticle

Tenofovir
Biopsy
biopsy
gels
Tissue

Development of a composite measure of product adherence, protocol compliance, and semen exposure using dna and protein biomarkers for topical HIV prevention studies

Jacot, T. A., Nelson, A., Thurman, A., Kashuba, A. D. M., Archer, D. F. & Doncel, G. F. Dec 9 2014 In : PLoS ONE. 9, 12, e114368

Research output: Contribution to journalArticle

Guideline Adherence
Applicators
Biomarkers
Semen
Tenofovir
20 Citations

Drug resistance and plasma viral RNA level after ineffective use of oral pre-exposure prophylaxis in women

Grant, R. M., Liegler, T., Defechereux, P., Kashuba, A. D. M., Taylor, D., Abdel-Mohsen, M., Deese, J., Fransen, K., De Baetselier, I., Crucitti, T., Bentley, G., Agingu, W., Ahmed, K. & Van Damme, L. Nov 25 2014 In : AIDS. 29, 3, p. 331-337 7 p.

Research output: Contribution to journalArticle

Tenofovir
Viral RNA
Drug Resistance
Placebos
HIV-1
18 Citations

Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention

Nicol, M. R., Fedoriw, Y., Mathews, M., Prince, H. M. A., Patterson, K. B., Geller, E., Mollan, K., Mathews, S., Kroetz, D. L. & Kashuba, A. D. M. 2014 In : Journal of Clinical Pharmacology. 54, 5, p. 574-583 10 p.

Research output: Contribution to journalArticle

HIV
Pharmaceutical Preparations
Tenofovir
Messenger RNA
Organic Anion Transport Protein 1
46 Citations

FEM-PrEP: Adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis

Corneli, A. L. , Deese, J. , Wang, M. , Taylor, D. , Ahmed, K. , Agot, K. , Lombaard, J. , Manongi, R. , Kapiga, S. , Kashuba, A. , Van Damme, L. , Agingu, W. , Ambia, J. , Asewe, J. , De Baetselier, I. , Chetty-Tulsee, S. , Chiduo, S. , Crucitti, T. , Fransen, K. , Gaddiel, J. G. & 32 others Kiernan, H., Kirkendale, S., Lalbahadur, T., Lanham, M., Lucky, T., Mak'Oketch, P., Makatu, S., Malahleha, M., Mandala, J., Mankalimeng, M., Masaki, M., Mastro, T., McKenna, K., Monedi, M. C., Mullins, S., Nanda, K., Odhiambo, J., Olango, I., Omullo, P., Omungo, Z., Owino, F., Parker, C., Ratlhagana, M., Reblin, I., Saylor, L., Siguntu, P., Skhosana, J. S., Troxler, A., Veena, V., Venkatasubramanian, L., Venter, G. & Wong, C. Jul 1 2014 In : Journal of Acquired Immune Deficiency Syndromes. 66, 3, p. 324-331 8 p.

Research output: Contribution to journalArticle

Tenofovir
Odds Ratio
Clinical Trials
Confidence Intervals
South Africa
107 Citations

HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat

Archin, N. M., Bateson, R., Tripathy, M. K., Crooks, A. M., Yang, K. H., Dahl, N. P., Kearney, M. F., Anderson, E. M., Coffin, J. M., Strain, M. C., Richman, D. D., Robertson, K. R., Kashuba, A. D., Bosch, R. J., Hazuda, D. J., Kuruc, J. D., Eron, J. J. & Margolis, D. M. Sep 1 2014 In : Journal of Infectious Diseases. 210, 5, p. 728-735 8 p.

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
RNA
HIV
Acetylation
17 Citations

HIV pre-exposure prophylaxis: Mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model

Veselinovic, M., Yang, K. H., LeCureux, J., Sykes, C., Remling-Mulder, L., Kashuba, A. D. M. & Akkina, R. Jan 1 2014 In : Virology. 464-465, 1, p. 253-263 11 p.

Research output: Contribution to journalArticle

Tenofovir
Tissue Distribution
Mucous Membrane
HIV
Pharmaceutical Preparations
17 Citations

Mapping antiretroviral drugs in tissue by IR-MALDESI MSI coupled to the Q Exactive and comparison with LC-MS/MS SRM assay

Barry, J. A., Robichaud, G., Bokhart, M. T., Thompson, C., Sykes, C., Kashuba, A. D. M. & Muddiman, D. C. 2014 In : Journal of the American Society for Mass Spectrometry. 25, 12, p. 2038-2047 10 p.

Research output: Contribution to journalArticle

Assays
Tissue
Imaging techniques
Pharmaceutical Preparations
Experiments
3 Citations

Measuring adherence by visual inspection of returned empty gel applicators in the CAPRISA 004 microbicide trial

Gengiah, T. N., Mansoor, L. E., Upfold, M., Naidoo, A., Yende-Zuma, N., Kashuba, A. D. M., Karim, Q. A. & Karim, S. S. A. 2014 In : AIDS and Behavior. 18, 5, p. 820-825 6 p.

Research output: Contribution to journalArticle

Anti-Infective Agents
Gels
Vagina
Proportional Hazards Models
HIV Infections

Pharmacokinetics and Pharmacodynamics of Anti-infective Agents

Pai, M. P., Cottrell, M. L., Kashuba, A. D. M. & Bertino, J. S. Aug 28 2014 Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 1, p. 252-262 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Citations

Pharmacokinetics of antiretrovirals in genital secretions and anatomic sites of HIV transmission: Implications for HIV prevention

Trezza, C. R. & Kashuba, A. D. M. Jan 1 2014 In : Clinical Pharmacokinetics. 53, 7, p. 611-624 14 p.

Research output: Contribution to journalReview article

Pharmacokinetics
HIV
Integrase Inhibitors
Clinical Trials
Reverse Transcriptase Inhibitors