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2018

Biomarker threshold adaptive designs for survival endpoints

Diao, G., Dong, J., Zeng, D., Ke, C., Rong, A. & Ibrahim, J. G. Feb 14 2018 (Accepted/In press) In : Journal of biopharmaceutical statistics. p. 1-17 17 p.

Research output: Contribution to journalArticle

Two-stage Design
Adaptive Design
Biomarkers
Survival
Subgroup

Efficient ℓ0-norm feature selection based on augmented and penalized minimization

Li, X., Xie, S., Zeng, D. & Wang, Y. Feb 10 2018 In : Statistics in medicine. 37, 3, p. 473-486 14 p.

Research output: Contribution to journalArticle

Biomarkers
Censored Data
Variable Selection
Feature Selection
Penalized Regression

Estimating causal log-odds ratio using the case-control sample and its application in the pharmaco-epidemiology study

Zhu, A., Zeng, D., Zhang, P. & Li, L. Jan 1 2018 (Accepted/In press) In : Statistical methods in medical research.

Research output: Contribution to journalArticle

Propensity Score
Causal Inference
Case-control
Odds Ratio
Epidemiology

Estimation and evaluation of linear individualized treatment rules to guarantee performance

Qiu, X., Zeng, D. & Wang, Y. Jun 1 2018 In : Biometrics. 74, 2, p. 517-528 12 p.

Research output: Contribution to journalArticle

Performance Guarantee
artificial intelligence
Learning systems
Machine Learning
Evaluation
Biosimilar Pharmaceuticals
Bioequivalence
Therapeutic Equivalency
Pharmacokinetics
Efficacy
2 Citations

Joint modeling of survival time and longitudinal outcomes with flexible random effects

Choi, J., Zeng, D., Olshan, A. F. & Cai, J. Jan 1 2018 In : Lifetime data analysis. 24, 1, p. 126-152 27 p.

Research output: Contribution to journalArticle

Joint Modeling
Survival Time
imidazole mustard
Random Effects
Joint Model

Mixture drug-count response model for the high-dimensional drug combinatory effect on myopathy

Wang, X., Zhang, P., Chiang, C. W., Wu, H., Shen, L., Ning, X., Zeng, D., Wang, L., Quinney, S. K., Feng, W. & Li, L. Feb 20 2018 In : Statistics in medicine. 37, 4, p. 673-686 14 p.

Research output: Contribution to journalArticle

Electronic Health Records
Muscular Diseases
Drugs
Count
High-dimensional
Primary Prevention
Chronic Renal Insufficiency
Blood Pressure
Confidence Intervals
Population

Semiparametric regression analysis for composite endpoints subject to componentwise censoring

Diao, G., Zeng, D., Ke, C., Ma, H., Jiang, Q. & Ibrahim, J. G. Jun 1 2018 In : Biometrika. 105, 2, p. 403-418 16 p.

Research output: Contribution to journalArticle

1 Citations

Translational biomedical informatics and pharmacometrics approaches in the drug interactions research

Zhang, P., Wu, H. Y., Chiang, C. W., Wang, L., Binkheder, S., Wang, X., Zeng, D., Quinney, S. K. & Li, L. Feb 1 2018 In : CPT: Pharmacometrics and Systems Pharmacology. 7, 2, p. 90-102 13 p.

Research output: Contribution to journalReview article

Drug interactions
Informatics
Drug Interactions
Drugs
Data Mining
2017

Control-based imputation for sensitivity analyses in informative censoring for recurrent event data

Gao, F., Liu, G. F., Zeng, D., Xu, L., Lin, B., Diao, G., Golm, G., Heyse, J. F. & Ibrahim, J. G. Nov 1 2017 In : Pharmaceutical statistics. 16, 6, p. 424-432 9 p.

Research output: Contribution to journalArticle

Informative Censoring
Recurrent Events
Multiple Imputation
Imputation
Missing Data

Estimating personalized diagnostic rules depending on individualized characteristics

Liu, Y., Wang, Y., Huang, C. & Zeng, D. Mar 30 2017 In : Statistics in medicine. 36, 7, p. 1099-1117 19 p.

Research output: Contribution to journalArticle

Screening
Diagnostics
Modality
Imaging
Diffusion Tensor Imaging
5 Citations

Heterogeneity in blood pressure transitions over the life course: Age-specific emergence of racial/ethnic and sex disparities in the United States

Hardy, S. T., Holliday, K. M., Chakladar, S., Engeda, J. C., Allen, N. B., Heiss, G., Lloyd-Jones, D. M., Schreiner, P. J., Shay, C. M., Lin, D., Zeng, D. & Avery, C. L. Jun 1 2017 In : JAMA Cardiology. 2, 6, p. 653-661 9 p.

Research output: Contribution to journalArticle

Prehypertension
Blood Pressure
African Americans
Nutrition Surveys
Hypertension

Joint partially linear model for longitudinal data with informative drop-outs

Kim, S., Zeng, D. & Taylor, J. M. G. Mar 1 2017 In : Biometrics. 73, 1, p. 72-82 11 p.

Research output: Contribution to journalArticle

dropouts
Partially Linear Model
Drop out
Longitudinal Data
Biomarkers
6 Citations

Mammographic Density Change With Estrogen and Progestin Therapy and Breast Cancer Risk

Byrne, C., Ursin, G., Martin, C. F., Peck, J. D., Cole, E. B., Zeng, D., Kim, E., Yaffe, M. D., Boyd, N. F., Heiss, G., McTiernan, A., Chlebowski, R. T., Lane, D. S., Manson, J. A. E., Wactawski-Wende, J. & Pisano, E. D. Sep 1 2017 In : Journal of the National Cancer Institute. 109, 9, djx001

Research output: Contribution to journalArticle

Progestins
Estrogens
Breast Neoplasms
Odds Ratio
Confidence Intervals

Maximum likelihood estimation for semiparametric regression models with multivariate interval-censored data

Zeng, D., Gao, F. & Lin, D. Y. Sep 1 2017 In : Biometrika. 104, 3, p. 505-525 21 p.

Research output: Contribution to journalArticle

Proportional Odds
Nonparametric Likelihood
Multivariate Failure Times
Current Status Data
Semiparametric Regression Model
Informative Dropout
Semiparametric Efficiency
Nonparametric Maximum Likelihood Estimator
Cox Model
Count Data

Occupational Exposures and Metabolic Syndrome among Hispanics/Latinos

Bulka, C. M., Daviglus, M. L., Persky, V. W., Durazo-Arvizu, R. A., Avilés-Santa, M. L., Gallo, L. C., Hosgood, H. D., Singer, R. H., Talavera, G. A., Thyagarajan, B., Zeng, D. & Argos, M. Nov 1 2017 In : Journal of Occupational and Environmental Medicine. 59, 11, p. 1047-1055 9 p.

Research output: Contribution to journalArticle

Occupational Exposure
Hispanic Americans
Abdominal Obesity
Hypertension
Triglycerides

On inference of control-based imputation for analysis of repeated binary outcomes with missing data

Gao, F., Liu, G., Zeng, D., Diao, G., Heyse, J. F. & Ibrahim, J. G. May 4 2017 In : Journal of biopharmaceutical statistics. 27, 3, p. 358-372 15 p.

Research output: Contribution to journalArticle

Binary Outcomes
Imputation
Missing Data
Clinical Trials
Biased

Pattern mixture models for clinical validation of biomarkers in the presence of missing data

Gao, F., Dong, J., Zeng, D., Rong, A. & Ibrahim, J. G. Aug 30 2017 In : Statistics in medicine. 36, 19, p. 2994-3004 11 p.

Research output: Contribution to journalArticle

Pattern-mixture Model
Biomarkers
Missing Data
Clinical Trials
Therapy

Penalized nonlinear mixed effects model to identify biomarkers that predict disease progression

Chen, H., Zeng, D. & Wang, Y. Jan 1 2017 In : Biometrics. 73, 4, p. 1343-1354 12 p.

Research output: Contribution to journalArticle

Nonlinear Mixed Effects Model
Biomarkers
Progression
disease course
Disease Progression
1 Citations

Potential Use of American College of Radiology BI-RADS Mammography Atlas for Reporting and Assessing Lesions Detected on Dedicated Breast CT Imaging: Preliminary Study

Jung, H. K., Kuzmiak, C. M., Kim, K. W., Choi, N. M., Kim, H. J., Langman, E. L., Yoon, S., Steen, D., Zeng, D. & Gao, F. Nov 1 2017 In : Academic radiology. 24, 11, p. 1395-1401 7 p.

Research output: Contribution to journalArticle

Atlases
Mammography
Radiology
Breast
Breast Neoplasms

Principal components adjusted variable screening

Liu, Z., Song, R., Zeng, D. & Zhang, J. Jun 1 2017 In : Computational Statistics and Data Analysis. 110, p. 134-144 11 p.

Research output: Contribution to journalArticle

Principal Components
Screening
Rats
Marginal Model
Model Misspecification

Proportional hazards model with a change point for clustered event data

Deng, Y., Zeng, D., Zhao, J. & Cai, J. Sep 1 2017 In : Biometrics. 73, 3, p. 835-845 11 p.

Research output: Contribution to journalArticle

Proportional Hazards Model
Change Point
Proportional Hazards Models
Hazards
risk factors

Semiparametric estimation of the accelerated failure time model with partly interval-censored data

Gao, F., Zeng, D. & Lin, D. Y. Jan 1 2017 In : Biometrics. 73, 4, p. 1161-1168 8 p.

Research output: Contribution to journalArticle

Semiparametric Efficiency
Accelerated Failure Time Model
Interval-censored Data
Kernel Estimation
acquired immunodeficiency syndrome

Semiparametric regression analysis of interval-censored competing risks data

Mao, L., Lin, D. Y. & Zeng, D. Sep 1 2017 In : Biometrics. 73, 3, p. 857-865 9 p.

Research output: Contribution to journalArticle

Semiparametric Regression
Competing Risks
Regression Analysis
Regression analysis
regression analysis

Semiparametric regression analysis of repeated current status data

Liang, B., Tong, X., Zeng, D. & Wang, Y. Jul 1 2017 In : Statistica Sinica. 27, 3, p. 1079-1100 22 p.

Research output: Contribution to journalArticle

Semiparametric Efficiency
Current Status Data
Semiparametric Regression
Recurrent Events
Regression Analysis

Semiparametric single-index model for estimating optimal individualized treatment strategy

Song, R., Luo, S., Zeng, D., Zhang, H. H., Lu, W. & Li, Z. Jan 1 2017 In : Electronic Journal of Statistics. 11, 1, p. 364-384 21 p.

Research output: Contribution to journalArticle

Sequential multiple assignment randomization trials with enrichment design

Liu, Y., Wang, Y. & Zeng, D. Jun 1 2017 In : Biometrics. 73, 2, p. 378-390 13 p.

Research output: Contribution to journalArticle

Random Allocation
Randomisation
Assignment
dropouts
Therapeutics

Statistical design of noninferiority multiple region clinical trials to assess global and consistent treatment effects

Diao, G., Zeng, D., Ibrahim, J. G., Rong, A., Lee, O., Zhang, K. & Chen, Q. Nov 2 2017 In : Journal of biopharmaceutical statistics. 27, 6, p. 933-944 12 p.

Research output: Contribution to journalArticle

Non-inferiority
Treatment Effects
Clinical Trials
Guidelines
Pharmaceutical Preparations

Structural social support and cardiovascular disease risk factors in Hispanic/Latino adults with diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Hernandez, R., Carnethon, M., Giachello, A. L., Penedo, F. J., Wu, D., Birnbaum-Weitzman, O., Giacinto, R. E., Gallo, L. C., Isasi, C. R., Schneiderman, N., Teng, Y., Zeng, D. & Daviglus, M. L. Feb 24 2017 (Accepted/In press) In : Ethnicity and Health. p. 1-15 15 p.

Research output: Contribution to journalArticle

Hispanic Americans
Social Support
chronic illness
social support
Cardiovascular Diseases

Targeting physical activity interventions for adults: When should intervention occur?

Holliday, K. M., Lin, D. Y., Chakladar, S., Castañeda, S. F., Daviglus, M. L., Evenson, K. R., Marquez, D. X., Qi, Q., Shay, C. M., Sotres-Alvarez, D., Vidot, D. C., Zeng, D. & Avery, C. L. Apr 1 2017 In : Preventive Medicine. 97, p. 13-18 6 p.

Research output: Contribution to journalArticle

Exercise
Hispanic Americans
Confidence Intervals
Demography
Population
2016

Comment

Chen, J., Liu, Y., Zeng, D., Song, R., Zhao, Y. & Kosorok, M. R. Jul 2 2016 In : Journal of the American Statistical Association. 111, 515, p. 942-947 6 p.

Research output: Contribution to journalComment/debate

Q-learning
Model Misspecification
Leukemia
Chemotherapy
Bayesian Model
2 Citations

Dedicated Three-dimensional Breast Computed Tomography: Lesion Characteristic Perception by Radiologists

Kuzmiak, C., Cole, E., Zeng, D., Tuttle, L., Steed, D. & Pisano, E. Jan 1 2016 In : Journal of Clinical Imaging Science. 6, 1, 14

Research output: Contribution to journalArticle

Breast
Tomography
Information Systems
Radiologists
Research Ethics Committees
1 Citations

Disparities in early transitions to obesity in contemporary multi-ethnic U.S. populations

Avery, C. L., Holliday, K. M., Chakladar, S., Engeda, J. C., Hardy, S. T., Reis, J. P., Schreiner, P. J., Shay, C. M., Daviglus, M. L., Heiss, G., Lin, D. Y. & Zeng, D. Jun 1 2016 In : PloS one. 11, 6, e0158025

Research output: Contribution to journalArticle

Mexican Americans
obesity
Obesity
Nutrition
Extrapolation

Estimating Treatment Effects for Recurrent Events in the Presence of Rescue Medications: An Application to the Immune Thrombocytopenia Study

Gao, F., Zeng, D., Wei, H., Wang, X. & Ibrahim, J. G. Aug 29 2016 (Accepted/In press) In : Statistics in Biosciences. p. 1-17 17 p.

Research output: Contribution to journalArticle

Recurrent Events
Idiopathic Thrombocytopenic Purpura
Treatment Effects
Platelets
Hemorrhage
6 Citations

Maximum likelihood estimation for semiparametric transformation models with interval-censored data

Zeng, D., Mao, L. & Lin, D. Y. Jun 23 2016 In : Biometrika. 103, 2, p. 253-271 19 p.

Research output: Contribution to journalArticle

Time-dependent Covariates
Interval-censored Data
Transformation Model
Maximum likelihood estimation
Semiparametric Model
2 Citations

Personalized Dose Finding Using Outcome Weighted Learning

Chen, G., Zeng, D. & Kosorok, M. R. Oct 1 2016 In : Journal of the American Statistical Association. 111, 516, p. 1509-1521 13 p.

Research output: Contribution to journalArticle

Dose Finding
Dose
Cohort Study
Randomized Trial
Continuous Distributions

Quantile regression models for current status data

Ou, F. S., Zeng, D. & Cai, J. Nov 1 2016 In : Journal of Statistical Planning and Inference. 178, p. 112-127 16 p.

Research output: Contribution to journalArticle

Current Status Data
Quantile Regression
Failure Time
Regression Model
Epidemiology

Rejoinder

Chen, G., Zeng, D. & Kosorok, M. R. Oct 1 2016 In : Journal of the American Statistical Association. 111, 516, p. 1543-1547 5 p.

Research output: Contribution to journalComment/debate

Reply to Comments

Zeng, D., Gao, F., Ibrahim, J. G., Hu, K. & Jia, C. Apr 30 2016 In : Statistics in Medicine. 35, 9, p. 1560 1 p.

Research output: Contribution to journalLetter

Sample Size
Human
Counting Process
Support Vector
Hazard
Hazards
Hazard Function
3 Citations

Using pilot data to size a two-arm randomized trial to find a nearly optimal personalized treatment strategy

Laber, E. B., Zhao, Y. Q., Regh, T., Davidian, M., Tsiatis, A., Stanford, J. B., Zeng, D., Song, R. & Kosorok, M. R. Apr 15 2016 In : Statistics in medicine. 35, 8, p. 1245-1256 12 p.

Research output: Contribution to journalArticle

Randomized Trial
Randomized Clinical Trial
Generative Models
Sample Size
Therapeutics
2 Citations

Variable selection for case-cohort studies with failure time outcome

Ni, A., Cai, J. & Zeng, D. Sep 1 2016 In : Biometrika. 103, 3, p. 547-562 16 p.

Research output: Contribution to journalArticle

Cohort Study
Failure Time
Variable Selection
Case-cohort Design
selection methods
2015
1 Citations

A counterfactual P -Value approach for benefit-risk assessment in clinical trials

Zeng, D., Chen, M. H., Ibrahim, J. G., Wei, R., Ding, B., Ke, C. & Jiang, Q. Jan 1 2015 In : Journal of Biopharmaceutical Statistics. 25, 3, p. 508-524 17 p.

Research output: Contribution to journalArticle

Risk Assessment
Clinical Trials
p-Value
Weights and Measures
Efficacy
3 Citations

Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling

Tao, R., Zeng, D., Franceschini, N., North, K. E., Boerwinkle, E. & Lin, D. Y. Apr 3 2015 In : Journal of the American Statistical Association. 110, 510, p. 560-572 13 p.

Research output: Contribution to journalArticle

Linear regression
Sequencing
Dependent
Simultaneous Inference
Genetic Association

Analysis of the Proportional Hazards Model With Sparse Longitudinal Covariates

Cao, H., Churpek, M. M., Zeng, D. & Fine, J. P. Jul 3 2015 In : Journal of the American Statistical Association. 110, 511, p. 1187-1196 10 p.

Research output: Contribution to journalArticle

Proportional Hazards Model
Covariates
Kernel Estimation
Kernel Methods
Time-varying Covariates
15 Citations

Doubly robust learning for estimating individualized treatment with censored data

Zhao, Y. Q., Zeng, D., Laber, E. B., Song, R., Yuan, M. & Kosorok, M. R. Jan 1 2015 In : Biometrika. 102, 1, p. 151-168 18 p.

Research output: Contribution to journalArticle

Censored Data
learning
Learning
Censoring
Survival
4 Citations

Hypothesis testing for two-stage designs with over or under enrollment

Zeng, D., Gao, F., Hu, K., Jia, C. & Ibrahim, J. G. Jul 20 2015 In : Statistics in Medicine. 34, 16, p. 2417-2426 10 p.

Research output: Contribution to journalArticle

Two-stage Design
Hypothesis Testing
Sample Size
Type I error
Normal Approximation
11 Citations

Impact of a rapid microarray-based assay for identification of positive blood cultures for treatment optimization for patients with streptococcal and enterococcal bacteremia

Roshdy, D. G., Tran, A., LeCroy, N., Zeng, D., Oud, F. S., Daniels, L. M., Weber, D. J., Alby, K. & Miller, M. B. Jan 1 2015 In : Journal of clinical microbiology. 53, 4, p. 1411-1414 4 p.

Research output: Contribution to journalArticle

Bacteremia
Anti-Bacterial Agents
Viridans Streptococci
Therapeutics
Blood Culture