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2018
1 Citations

A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia

Gonçalves, V. F., Cappi, C., Hagen, C. M., Sequeira, A., Vawter, M. P., Derkach, A., Zai, C. C., Hedley, P. L., Bybjerg-Grauholm, J., Pouget, J. G., Cuperfain, A. B., Sullivan, P. F., Christiansen, M., Kennedy, J. L. & Sun, L. May 1 2018 In : Biological psychiatry. 83, 9, p. 780-789 10 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Schizophrenia
Psychiatry
Genes
Genomics

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

Coleman, J. R. I., Bryois, J., Gaspar, H. A., Jansen, P. R., Savage, J. E., Skene, N., Plomin, R., Muñoz-Manchado, A. B., Linnarsson, S., Crawford, G., Hjerling-Leffler, J., Sullivan, P. F., Posthuma, D. & Breen, G. Mar 8 2018 (Accepted/In press) In : Molecular Psychiatry. p. 1-16 16 p.

Research output: Contribution to journalArticle

Genetic Loci
Intelligence
Meta-Analysis
Genome-Wide Association Study
Genes

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model

Wray, N. R., Wijmenga, C., Sullivan, P. F., Yang, J. & Visscher, P. M. Jun 14 2018 In : Cell. 173, 7, p. 1573-1580 8 p.

Research output: Contribution to journalReview article

Genes
Precision Medicine
Research Design

Developmental delay, treatment-resistant psychosis, and early-onset dementia in a man with 22q11 deletion syndrome and huntington's disease

Farrell, M., Lichtenstein, M., Crowley, J. J., Filmyer, D. M., Lázaro-Muñoz, G., Shaughnessy, R. A., Mackenzie, I. R., Hirsch-Reinshagen, V., Stowe, R., Evans, J. P., Berg, J. S., Szatkiewicz, J., Josiassen, R. C. & Sullivan, P. F. May 1 2018 In : American Journal of Psychiatry. 175, 5, p. 400-407 8 p.

Research output: Contribution to journalArticle

22q11 Deletion Syndrome
Huntington Disease
Psychotic Disorders
Dementia
Therapeutics

Examining the role of common and rare mitochondrial variants in schizophrenia

Gonçalves, V. F., Giamberardino, S. N., Crowley, J. J., Vawter, M. P., Saxena, R., Bulik, C. M., Yilmaz, Z., Hultman, C. M., Sklar, P., Kennedy, J. L., Sullivan, P. F. & Knight, J. Jan 1 2018 In : PloS one. 13, 1, 0191153

Research output: Contribution to journalArticle

PL/1 (programming language)
Genetic Predisposition to Disease
Mitochondrial DNA
Genetic Markers
Sweden

Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes

Stokowy, T., Polushina, T., Sønderby, I. E., Karlsson, R., Giddaluru, S., Le Hellard, S., Bergen, S. E., Sullivan, P. F., Andreassen, O. A., Djurovic, S., Hultman, C. M. & Steen, V. M. Dec 1 2018 In : Scientific Reports. 8, 1, 6915

Research output: Contribution to journalArticle

Schizophrenia
Lipids
Genes
Exome
Genome-Wide Association Study
1 Citations

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

23andMe Research Team, Agee, Alipanahi, Auton, Bell, Bryc, Elson, Fontanillas, Furlotte, Hinds, Huber, Kleinman, Litterman, McCreight, McIntyre, Mountain, Noblin, Northover, Pitts, Sathirapongsasuti & 7 others Sazonova, Shelton, Shringarpure, Tian, Tung, Vacic & Wilson Dec 1 2018 In : Nature Communications. 9, 1, 3819

Research output: Contribution to journalArticle

phenotype
genome
Genome-Wide Association Study
Depression
Phenotype

MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission

He, E., Lozano, M. A. G., Stringer, S., Watanabe, K., Sakamoto, K., Oudsten, F. D., Koopmans, F., Giamberardino, S. N., Hammerschlag, A., Niels Cornelisse, L., Li, K. W., van Weering, J., Posthuma, D., Smit, A. B., Sullivan, P. F. & Verhage, M. Jun 1 2018 In : Human molecular genetics. 27, 11, p. 1879-1891 13 p.

Research output: Contribution to journalArticle

Internal-External Control
Synaptic Transmission
Synapses
Schizophrenia
Proteomics

Pamela Sklar 1959–2017

Sullivan, P. F., O’Donovan, M. C. & Craddock, N. Jan 25 2018 (Accepted/In press) In : Nature neuroscience. 1 p.

Research output: Contribution to journalArticle

Psychiatry
Medicine

Protein instability, haploinsufficiency, and cortical hyper-excitability underlie STXBP1 encephalopathy

Kovačević, J., Maroteaux, G., Schut, D., Loos, M., Dubey, M., Pitsch, J., Remmelink, E., Koopmans, B., Crowley, J., Cornelisse, L. N., Sullivan, P. F., Schoch, S., Toonen, R. F., Stiedl, O. & Verhage, M. May 1 2018 In : Brain. 141, 5, p. 1350-1374 25 p.

Research output: Contribution to journalArticle

Haploinsufficiency
Brain Diseases
Proteins
etiracetam
Electroencephalography
17 Citations

Psychiatric genomics: An update and an Agenda

Psychiatric Genomics Consortium Coordinating Committee Jan 1 2018 In : American Journal of Psychiatry. 175, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Psychotropic Drugs
Genomics
Mental Disorders
Psychiatry
1 Citations

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Gusev, A., Mancuso, N., Won, H., Kousi, M., Finucane, H. K., Reshef, Y., Song, L., Safi, A., McCarroll, S., Neale, B. M., Ophoff, R. A., O'Donovan, M. C., Crawford, G. E., Geschwind, D. H., Katsanis, N., Sullivan, P. F., Pasaniuc, B. & Price, A. L. Apr 1 2018 In : Nature Genetics. 50, 4, p. 538-548 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Transcriptome
Chromatin
Schizophrenia
Genes
2017
1 Citations

A Powerful Test for SNP Effects on Multivariate Binary Outcomes Using Kernel Machine Regression

Davenport, C. A., Maity, A., Sullivan, P. F. & Tzeng, J. Y. Mar 24 2017 (Accepted/In press) In : Statistics in Biosciences. p. 1-22 22 p.

Research output: Contribution to journalArticle

Kernel Machines
Binary Outcomes
Single Nucleotide Polymorphism
Regression
Polymorphism
3 Citations

Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence

Clark, S. L. , McClay, J. L. , Adkins, D. E. , Kumar, G. , Aberg, K. A. , Nerella, S. , Xie, L. , Collins, A. L. , Crowley, J. J. , Quackenbush, C. R. , Hilliard, C. E. , Shabalin, A. A. , Vrieze, S. I. , Peterson, R. E. , Copeland, W. E. , Silberg, J. L. , McGue, M. , Maes, H. , Iacono, W. G. , Sullivan, P. F. & 2 others Costello, E. J. & van den Oord, E. J. Jan 1 2017 In : Alcoholism: Clinical and Experimental Research. 41, 4, p. 711-718 8 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Alcoholism
Genes
Alcohols
Alcohol Dehydrogenase
2 Citations

Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa

Yilmaz, Z., Szatkiewicz, J. P., Crowley, J. J., Ancalade, N., Brandys, M. K., Van Elburg, A., De Kovel, C. G. F., Adan, R. A. H., Hinney, A., Hebebrand, J., Gratacos, M., Fernandez-Aranda, F., Escaramis, G., Gonzalez, J. R., Estivill, X., Zeggini, E., Sullivan, P. F. & Bulik, C. M. Jan 1 2017 In : Psychiatric Genetics. 27, 4, p. 152-158 7 p.

Research output: Contribution to journalArticle

Anorexia Nervosa
Psychiatry
Neurodevelopmental Disorders
Quality Control
Sample Size
8 Citations

Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

Liu, X., Finucane, H. K., Gusev, A., Bhatia, G., Gazal, S., O'Connor, L., Bulik-Sullivan, B., Wright, F. A., Sullivan, P. F., Neale, B. M. & Price, A. L. Apr 6 2017 In : American Journal of Human Genetics. 100, 4, p. 605-616 12 p.

Research output: Contribution to journalArticle

Gene Expression Regulation
Histone Code
Gene Expression

Genetics of tinnitus: Time to biobank phantom sounds

Cederroth, C. R., Kähler, A. K., Sullivan, P. F. & Lopez-Escamez, J. A. Sep 4 2017 In : Frontiers in Genetics. 8, SEP, 110

Research output: Contribution to journalArticle

Neuropsychiatry
Tinnitus
Genome-Wide Association Study
Phantom Limb
Sensory Deprivation
20 Citations

Genomes of the mouse collaborative cross

Srivastava, A., Morgan, A. P., Najarian, M. L., Sarsani, V. K., Sigmon, J. S., Shorter, J. R., Kashfeen, A., McMullan, R. C., Williams, L. H., Giusti-Rodríguez, P., Ferris, M. T., Sullivan, P., Hock, P., Miller, D. R., Bell, T. A., McMillan, L., Churchill, G. A. & De Villena, F. P. M. Jun 1 2017 In : Genetics. 206, 2, p. 537-556 20 p.

Research output: Contribution to journalArticle

Genetic Crosses
Genetic Drift
Inbred Strains Mice
Chromosome Mapping
Quantitative Trait Loci

How Good Were Candidate Gene Guesses in Schizophrenia Genetics?

Sullivan, P. F. Nov 15 2017 In : Biological psychiatry. 82, 10, p. 696-697 2 p.

Research output: Contribution to journalComment/debate

Schizophrenia
Genes
3 Citations

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

Nguyen, H. T. , Bryois, J. , Kim, A. , Dobbyn, A. , Huckins, L. M. , Munoz-Manchado, A. B. , Ruderfer, D. M. , Genovese, G. , Fromer, M. , Xu, X. , Pinto, D. , Linnarsson, S. , Verhage, M. , Smit, A. B. , Hjerling-Leffler, J. , Buxbaum, J. D. , Hultman, C. , Sklar, P. , Purcell, S. M. , Lage, K. & 3 others He, X., Sullivan, P. F. & Stahl, E. A. Dec 20 2017 In : Genome Medicine. 9, 1, 114

Research output: Contribution to journalArticle

Bayes Theorem
Autistic Disorder
Intellectual Disability
Epilepsy
Schizophrenia
2 Citations

Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia

Leonenko, G., Richards, A. L., Walters, J. T., Pocklington, A., Chambert, K., Al Eissa, M. M., Sharp, S. I., O'Brien, N. L., Curtis, D., Bass, N. J., McQuillin, A., Hultman, C., Moran, J. L., McCarroll, S. A., Sklar, P., Neale, B. M., Holmans, P. A., Owen, M. J., Sullivan, P. F. & O'Donovan, M. C. Oct 1 2017 In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 174, 7, p. 724-731 8 p.

Research output: Contribution to journalArticle

National-scale precision medicine for psychiatric disorders in Sweden

Bergen, S. E. & Sullivan, P. F. Jan 1 2017 (Accepted/In press) In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

Research output: Contribution to journalArticle

Precision Medicine
Genome-Wide Association Study
Genetic Association Studies
Depressive Disorder
Sweden
3 Citations

Obstetrical, pregnancy and socio-economic predictors for new-onset severe postpartum psychiatric disorders in primiparous women

Meltzer-Brody, S., Maegbaek, M. L., Medland, S. E., Miller, W. C., Sullivan, P. & Munk-Olsen, T. Jun 1 2017 In : Psychological medicine. 47, 8, p. 1427-1441 15 p.

Research output: Contribution to journalArticle

Postpartum Period
Psychiatry
Economics
Pregnancy
Confidence Intervals
1 Citations

Schizophrenia and the dynamic genome

Sullivan, P. F. Mar 2 2017 In : Genome Medicine. 9, 1, 22

Research output: Contribution to journalComment/debate

Schizophrenia
Genome
21 Citations

Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

Duncan, L. , Yilmaz, Z. , Gaspar, H. , Walters, R. , Goldstein, J. , Anttila, V. , Bulik-Sullivan, B. , Ripke, S. , Thornton, L. , Hinney, A. , Daly, M. , Sullivan, P. F. , Zeggini, E. , Breen, G. , Bulik, C. M. , Duncan, L. , Yilmaz, Z. , Gaspar, H. , Walters, R. , Goldstein, J. & 216 others Anttila, V., Bulik-Sullivan, B., Ripke, S., Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Aschauer, H., Baker, J., Barrett, J., Bencko, V., Bergen, A., Berrettini, W., Birgegård, A., Boni, C., Perica, V. B., Brandt, H., Burghardt, R., Carlberg, L., Cassina, M., Cesta, C., Cichon, S., Clementi, M., Cohen-Woods, S., Coleman, J., Cone, R., Courtet, P., Crawford, S., Crow, S., Crowley, J., Danner, U., Davis, O., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J., Danielle, D. N., Dikeos, D., Dina, C., Ding, B., Dmitrzak-Weglarz, M., Docampo, E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Espeseth, T., Estivill, X., Favaro, A., Fernández-Aranda, F., Fichter, M., Finan, C., Fischer, K., Floyd, J., Föcker, M., Foretova, L., Forzan, M., Fox, C., Franklin, C., Gaborieau, V., Gallinger, S., Gambaro, G., Giegling, I., Gonidakis, F., Gorwood, P., Gratacos, M., Guillaume, S., Guo, Y., Hakonarson, H., Halmi, K., Harrison, R., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S., Hendriks, J., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Hilliard, C., Huckins, L., Hudson, J., Huemer, J., Imgart, H., Inoko, H., Jall, S., Jamain, S., Janout, V., Jiménez-Murcia, S., Johnson, C., Jordan, J., Julià, A., Juréus, A., Kalsi, G., Kaplan, A., Kaprio, J., Karhunen, L., Karwautz, A., Kas, M., Kaye, W., Kennedy, M., Kennedy, J., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klareskog, L., Klump, K., Knudsen, G. P., Koeleman, B., Koubek, D., La Via, M., Landén, M., Le Hellard, S., Leboyer, M., Levitan, R., Li, D., Lichtenstein, P., Lilenfeld, L., Lissowska, J., Lundervold, A., Magistretti, P., Maj, M., Mannik, K., Marsal, S., Kaminska, D., Martin, N., Mattingsdal, M., McDevitt, S., McGuffin, P., Merl, E., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, J., Mitchell, K., Monteleone, P., Monteleone, A. M., Montgomery, G., Mortensen, P., Munn-Chernoff, M., Müller, T., Nacmias, B., Navratilova, M., Nilsson, I., Norring, C., Ntalla, I., Ophoff, R., O’Toole, J., Palotie, A., Pantel, J., Papezova, H., Parker, R., Pinto, D., Rabionet, R., Raevuori, A., Rajewski, A., Ramoz, N., William Rayner, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S., Schmidt, U., Schork, N., Schosser, A., Scott, L., Seitz, J., Slachtova, L., Sladek, R., Eline Slagboom, P., Slof-Op ’t Landt, M., Slopien, A., Smith, T., Soranzo, N., Sorbi, S., Southam, L., Steen, V., Strengman, E., Strober, M., Szatkiewicz, J., Szeszenia-Dabrowska, N., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tschöp, M., Tsitsika, A., Tziouvas, K., van Elburg, A., van Furth, E., Wade, T., Wagner, G., Walton, E., Watson, H., Wichmann, H. E., Widen, E., Woodside, B., Yanovski, J., Yao, S., Zerwas, S., Zipfel, S., Thornton, L., Hinney, A., Daly, M., Sullivan, P. F., Zeggini, E., Breen, G. & Bulik, C. M. Sep 1 2017 In : American Journal of Psychiatry. 174, 9, p. 850-858 9 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
Anorexia Nervosa
Linkage Disequilibrium
Genetic Predisposition to Disease
14 Citations

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

Singh, T. , Walters, J. T. R. , Johnstone, M. , Curtis, D. , Suvisaari, J. , Torniainen, M. , Rees, E. , Iyegbe, C. , Blackwood, D. , McIntosh, A. M. , Kirov, G. , Geschwind, D. , Murray, R. M. , Di Forti, M. , Bramon, E. , Gandal, M. , Hultman, C. M. , Sklar, P. , Palotie, A. , Sullivan, P. F. & 3 others O'Donovan, M. C., Owen, M. J. & Barrett, J. C. Aug 1 2017 In : Nature Genetics. 49, 8, p. 1167-1173 7 p.

Research output: Contribution to journalArticle

2016
1 Citations

Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses

Clark, S. L., McClay, J. L., Adkins, D. E., Aberg, K. A., Kumar, G., Nerella, S., Xie, L., Collins, A. L., Crowley, J. J., Quakenbush, C. R., Hillard, C. E., Gao, G., Shabalin, A. A., Peterson, R. E., Copeland, W. E., Silberg, J. L., Maes, H., Sullivan, P. F., Elizabeth, J. C. & van den Oord, E. J. May 1 2016 In : Nicotine and Tobacco Research. 18, 5, p. 626-631 6 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Genome-Wide Association Study
Gene Frequency
Meta-Analysis
Smoking
12 Citations

Heritability of perinatal depression and genetic overlap with nonperinatal depression

Viktorin, A., Meltzer-Brody, S., Kuja-Halkola, R., Sullivan, P. F., Landén, M., Lichtenstein, P. & Magnusson, P. K. E. Feb 1 2016 In : American Journal of Psychiatry. 173, 2, p. 158-165 8 p.

Research output: Contribution to journalArticle

Depression
Siblings
Postpartum Depression
Twin Studies
Counseling
90 Citations

Integrative approaches for large-scale transcriptome-wide association studies

Gusev, A. , Ko, A. , Shi, H. , Bhatia, G. , Chung, W. , Penninx, B. W. J. H. , Jansen, R. , De Geus, E. J. C. , Boomsma, D. I. , Wright, F. A. , Sullivan, P. F. , Nikkola, E. , Alvarez, M. , Civelek, M. , Lusis, A. J. , Lehtimäki, T. , Raitoharju, E. , Kähönen, M. , Seppälä, I. , Raitakari, O. T. & 5 others Kuusisto, J., Laakso, M., Price, A. L., Pajukanta, P. & Pasaniuc, B. Mar 1 2016 In : Nature Genetics. 48, 3, p. 245-252 8 p.

Research output: Contribution to journalArticle

Transcriptome
Gene Expression
Genome-Wide Association Study
Phenotype
Genes
11 Citations

Nationwide genomic study in Denmark reveals remarkable population homogeneity

Athanasiadis, G., Cheng, J. Y., Vilhjálmsson, B. J., Jørgensen, F. G., Als, T. D., Le Hellard, S., Espeseth, T., Sullivan, P. F., Hultman, C. M., Kjærgaard, P. C., Schierup, M. H. & Mailund, T. Oct 1 2016 In : Genetics. 204, 2, p. 711-722 12 p.

Research output: Contribution to journalArticle

Denmark
Norway
Sweden
Population
History
1 Citations

One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins

Magnusson, P. K. E., Lee, D., Chen, X., Szatkiewicz, J., Pramana, S., Teo, S., Sullivan, P. F., Feuk, L. & Pawitan, Y. Apr 1 2016 In : Twin Research and Human Genetics. 19, 2, p. 97-103 7 p.

Research output: Contribution to journalArticle

Monozygotic Twins
Genome
Exons
Dizygotic Twins
Twin Studies
23 Citations

Polygenic overlap between schizophrenia risk and antipsychotic response: A genomic medicine approach

Ruderfer, D. M., Charney, A. W., Readhead, B., Kidd, B. A., Kähler, A. K., Kenny, P. J., Keiser, M. J., Moran, J. L., Hultman, C. M., Scott, S. A., Sullivan, P. F., Purcell, S. M., Dudley, J. T. & Sklar, P. Apr 1 2016 In : The Lancet Psychiatry. 3, 4, p. 350-357 8 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Schizophrenia
Medicine
Genes
Therapeutics
26 Citations

The mouse universal genotyping array: From substrains to subspecies

Morgan, A. P. , Fu, C. P. , Kao, C. Y. , Welsh, C. E. , Didion, J. P. , Yadgary, L. , Hyacinth, L. , Ferris, M. T. , Bell, T. A. , Miller, D. R. , Giusti-Rodriguez, P. , Nonneman, R. J. , Cook, K. D. , Whitmire, J. K. , Gralinski, L. E. , Keller, M. , Attie, A. D. , Churchill, G. A. , Petkov, P. , Sullivan, P. F. & 3 others Brennan, J. R., McMillan, L. & Villena, F. P. M. D. Jan 1 2016 In : G3: Genes, Genomes, Genetics. 6, 2, p. 263-279 17 p.

Research output: Contribution to journalArticle

Population Genetics
Quality Control
Single Nucleotide Polymorphism
Genome
Population
19 Citations

Translating genome-wide association findings into new therapeutics for psychiatry

Breen, G., Li, Q., Roth, B. L., O'Donnell, P., Didriksen, M., Dolmetsch, R., O'Reilly, P. F., Gaspar, H. A., Manji, H., Huebel, C., Kelsoe, J. R., Malhotra, D., Bertolino, A., Posthuma, D., Sklar, P., Kapur, S., Sullivan, P. F., Collier, D. A. & Edenberg, H. J. Oct 26 2016 In : Nature neuroscience. 19, 11, p. 1392-1396 5 p.

Research output: Contribution to journalReview article

Psychiatry
Genome
Genome-Wide Association Study
Genomics
Sample Size
2 Citations

What next in schizophrenia genetics for the psychiatric genomics consortium?

Corvin, A. & Sullivan, P. F. May 1 2016 In : Schizophrenia Bulletin. 42, 3, p. 538-541 4 p.

Research output: Contribution to journalReview article

Genome-Wide Association Study
Genomics
Psychiatry
Schizophrenia
2015
17 Citations

A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2

Didion, J. P. , Morgan, A. P. , Clayshulte, A. M. F. , Mcmullan, R. C. , Yadgary, L. , Petkov, P. M. , Bell, T. A. , Gatti, D. M. , Crowley, J. J. , Hua, K. , Aylor, D. L. , Bai, L. , Calaway, M. , Chesler, E. J. , French, J. E. , Geiger, T. R. , Gooch, T. J. , Garland, T. , Harrill, A. H. , Hunter, K. & 16 others McMillan, L., Holt, M., Miller, D. R., O'Brien, D. A., Paigen, K., Pan, W., Rowe, L. B., Shaw, G. D., Simecek, P., Sullivan, P. F., Svenson, K. L., Weinstock, G. M., Threadgill, D. W., Pomp, D., Churchill, G. A. & Pardo-Manuel de Villena, F. Jan 1 2015 In : PLoS genetics. 11, 2, p. 1-29 29 p., e1004850

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 2
chromosome
Mothers
meiotic drive
chromosomes
60 Citations

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance

Crowley, J. J. , Zhabotynsky, V. , Sun, W. , Huang, S. , Pakatci, I. K. , Kim, Y. , Wang, J. R. , Morgan, A. P. , Calaway, J. D. , Aylor, D. L. , Yun, Z. , Bell, T. A. , Buus, R. J. , Calaway, M. E. , Didion, J. P. , Gooch, T. J. , Hansen, S. D. , Robinson, N. N. , Shaw, G. D. , Spence, J. S. & 21 others Quackenbush, C. R., Barrick, C. J., Nonneman, R. J., Kim, K., Xenakis, J., Xie, Y., Valdar, W., Lenarcic, A. B., Wang, W., Welsh, C. E., Fu, C. P., Zhang, Z., Holt, J., Guo, Z., Threadgill, D. W., Tarantino, L. M., Miller, D. R., Zou, F., McMillan, L., Sullivan, P. F. & De Villena, F. P. M. Jan 1 2015 In : Nature Genetics. 47, 4, p. 353-360 8 p.

Research output: Contribution to journalArticle

Allelic Imbalance
Alleles
Gene Expression
Genetic Transcription
Single Nucleotide Polymorphism
2 Citations

A New Method for Detecting Associations with Rare Copy-Number Variants

The Swedish Schizophrenia Consortium Jan 1 2015 In : PLoS genetics. 11, 10, e1005403

Research output: Contribution to journalArticle

DNA Copy Number Variations
methodology
loci
behavior disorders
Gene Dosage
8 Citations

Biological pathways and networks implicated in psychiatric disorders

Sullivan, P. F. & Posthuma, D. Apr 1 2015 In : Current Opinion in Behavioral Sciences. 2, p. 58-68 11 p.

Research output: Contribution to journalReview article

Psychiatry
Multifactorial Inheritance
Bipolar Disorder
Genes
Schizophrenia
12 Citations

CNV concordance in 1,097 MZ twin pairs

Abdellaoui, A., Ehli, E. A., Hottenga, J. J., Weber, Z., Mbarek, H., Willemsen, G., Van Beijsterveldt, T., Brooks, A., Hudziak, J. J., Sullivan, P. F., De Geus, E. J., Davies, G. E. & Boomsma, D. I. Feb 11 2015 In : Twin Research and Human Genetics. 18, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Monozygotic Twins
Cheek
DNA
Epithelium
Overlapping Genes
7 Citations

Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use

Clark, S. L., Aberg, K. A., Nerella, S., Kumar, G., Mcclay, J. L., Chen, W., Xie, L. Y., Harada, A., Shabalin, A. A., Gao, G., Bergen, S. E., Hultman, C. M., Magnusson, P. K. E., Sullivan, P. F. & van den Oord, E. J. C. G. Aug 1 2015 In : Alcoholism: Clinical and Experimental Research. 39, 8, p. 1396-1405 10 p.

Research output: Contribution to journalArticle

Methylation
Alcohols
Association reactions
Single Nucleotide Polymorphism
Polymorphism
10 Citations

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

Pers, T. H., Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N. & Schizophrenia Working Group of the Psychiatric Genomics Consortium Aug 17 2015 In : Human Molecular Genetics. 25, 6, p. 1247-1254 8 p., ddw007

Research output: Contribution to journalArticle

Ion Channels
Schizophrenia
Genes
Odds Ratio
Post-Synaptic Density
9 Citations

Disruption of the MicroRNA 137 primary transcript results in early embryonic lethality in mice

Crowley, J. J., Collins, A. L., Lee, R. J., Nonneman, R. J., Farrell, M. S., Ancalade, N., Mugford, J. W., Agster, K. L., Nikolova, V. D., Moy, S. S. & Sullivan, P. F. Jan 1 2015 In : Biological Psychiatry. 77, 2, p. e5-e7

Research output: Contribution to journalLetter

Mammalian Embryo
Fetal Diseases
MicroRNAs
Inbred C57BL Mouse
Knockout Mice
11 Citations

Educational attainment influences levels of homozygosity through migration and assortative mating

Abdellaoui, A., Hottenga, J. J., Willemsen, G., Bartels, M., Van Beijsterveldt, T., Ehli, E. A., Davies, G. E., Brooks, A., Sullivan, P. F., Penninx, B. W. J. H., De Geus, E. J. & Boomsma, D. I. Mar 3 2015 In : PloS one. 10, 3, e0118935

Research output: Contribution to journalArticle

assortative mating
homozygosity
education
ancestry
spouses
1 Citations

Erratum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance (Nature Genetics (2015) 47 (353-360))

Crowley, J. J. , Zhabotynsky, V. , Sun, W. , Huang, S. , Pakatci, I. K. , Kim, Y. , Wang, J. R. , Morgan, A. P. , Calaway, J. D. , Aylor, D. L. , Yun, Z. , Bell, T. A. , Buus, R. J. , Calaway, M. E. , Didion, J. P. , Gooch, T. J. , Hansen, S. D. , Robinson, N. N. , Shaw, G. D. , Spence, J. S. & 21 others Quackenbush, C. R., Barrick, C. J., Nonneman, R. J., Kim, K., Xenakis, J., Xie, Y., Valdar, W., Lenarcic, A. B., Wang, W., Welsh, C. E., Fu, C. P., Zhang, Z., Holt, J., Guo, Z., Threadgill, D. W., Tarantino, L. M., Miller, D. R., Zou, F., McMillan, L., Sullivan, P. F. & De Villena, F. P. M. Jan 1 2015 In : Nature Genetics. 47, 6, 1 p.

Research output: Contribution to journalComment/debate

Allelic Imbalance
Alleles
Gene Expression
72 Citations

Evaluating historical candidate genes for schizophrenia

Farrell, M. S., Werge, T., Sklar, P., Owen, M. J., Ophoff, R. A., O'donovan, M. C., Corvin, A., Cichon, S. & Sullivan, P. F. Jan 1 2015 In : Molecular Psychiatry. 20, 5, p. 555-562 8 p.

Research output: Contribution to journalArticle

Schizophrenia
Genes
Genetic Association Studies
Meta-Analysis
Research Personnel
2 Citations

Fast eQTL Analysis for Twin Studies

Yin, Z., Xia, K., Chung, W., Sullivan, P. F. & Zou, F. Jul 1 2015 In : Genetic Epidemiology. 39, 5, p. 357-365 9 p.

Research output: Contribution to journalArticle

Twin Studies
Quantitative Trait Loci
Netherlands
Single Nucleotide Polymorphism
Psychiatry
2 Citations

Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences

Giniatullina, A. , Maroteaux, G. , Geerts, C. J. , Koopmans, B. , Loos, M. , Klaassen, R. , Chen, N. , van der Schors, R. C. , van Nierop, P. , Li, K. W. , de Jong, J. , Altrock, W. D. , Cornelisse, L. N. , Toonen, R. F. , van der Sluis, S. , Sullivan, P. F. , Stiedl, O. , Posthuma, D. , Smit, A. B. , Groffen, A. J. & 1 others Verhage, M. Aug 6 2015 In : Neuroscience. 300, p. 518-538 21 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Phenotype
Calcium
Genetic Heterogeneity
Synaptic Vesicles
9 Citations

Genetics of disease: Associations with depression

Sullivan, P. F. Jul 30 2015 In : Nature. 523, 7562, p. 539-540 2 p.

Research output: Contribution to journalShort survey

Inborn Genetic Diseases
7 Citations

Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood

Adkins, D. E., Clark, S. L., Copeland, W. E., Kennedy, M., Conway, K., Angold, A., Maes, H., Liu, Y., Kumar, G., Erkanli, A., Patkar, A. A., Silberg, J., Brown, T. H., Fergusson, D. M., Horwood, L. J., Eaves, L., Van Den Oord, E. J. C. G., Sullivan, P. F. & Costello, E. J. Jan 1 2015 In : Twin Research and Human Genetics. 18, 4, p. 335-347 13 p.

Research output: Contribution to journalArticle

Meta-Analysis
Genome
Alcohol Drinking
Genotype
GABA Plasma Membrane Transport Proteins