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2018
6 Citations

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery

Zhang, Y., Wang, J., Yu, J., Wen, D., Kahkoska, A. R., Lu, Y., Zhang, X., Buse, J. B. & Gu, Z., Apr 5 2018, In : Small. 14, 14, 1704181

Research output: Contribution to journalArticle

Controlled drug delivery
Glucose sensors
Glucose Oxidase
Glucose oxidase
Insulin
Dipeptidyl-Peptidase IV Inhibitors
Hypoglycemic Agents
Thiazolidinediones
Heart Failure
Propensity Score

Can We RISE to the Challenge of Youth-Onset Type 2 Diabetes?

Buse, J. B., D'Alessio, D. A. & Riddle, M. C., Aug 1 2018, In : Diabetes Care. 41, 8, p. 1560-1562 3 p.

Research output: Contribution to journalComment/debate

Type 2 Diabetes Mellitus
14 Citations

Cardiovascular outcomes trials in type 2 diabetes: Where Do We Go From Here? Ref lections From a Diabetes Care Editors' Expert Forum

Cefalu, W. T., Kaul, S., Gerstein, H. C., Holman, R. R., Zinman, B., Skyler, J. S., Green, J. B., Buse, J. B., Inzucchi, S. E., Leiter, L. A., Raz, I., Rosenstock, J. & Riddle, M. C., Jan 1 2018, In : Diabetes care. 41, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Drug Approval
Drug Industry
United States Food and Drug Administration
Pharmaceutical Preparations
35 Citations

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis

EXSCEL Study Group, Feb 1 2018, (Accepted/In press) In : The Lancet Diabetes and Endocrinology. p. 105-113 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Meta-Analysis
Mortality
Safety
Pharmaceutical Preparations
3 Citations
pioglitazone
Thiazolidinediones
Dipeptidyl-Peptidase IV Inhibitors
Hypoglycemic Agents
Urinary Bladder Neoplasms
3 Citations

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Wang, J., Ye, Y., Yu, J., Kahkoska, A. R., Zhang, X., Wang, C., Sun, W., Corder, R. D., Chen, Z., Khan, S. A., Buse, J. B. & Gu, Z., Mar 27 2018, In : ACS Nano. 12, 3, p. 2466-2473 8 p.

Research output: Contribution to journalArticle

Sulfur hexafluoride circuit breakers
insulin
Insulin
glucose
Glucose
23 Citations

Day-to-day fasting glycaemic variability in DEVOTE: associations with severe hypoglycaemia and cardiovascular outcomes (DEVOTE 2)

on behalf of the DEVOTE Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Hypoglycemia
Fasting
Breakfast
Blood Glucose
Mortality
9 Citations

DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality

on behalf of the DEVOTE Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

Hypoglycemia
Mortality
Type 2 Diabetes Mellitus
Safety
Hypoglycemic Agents

DEVOTE 5: Evaluating the Short-Term Cost-Utility of Insulin Degludec Versus Insulin Glargine U100 in Basal–Bolus Regimens for Type 2 Diabetes in the UK

on behalf of the DEVOTE Study Group, Jun 1 2018, In : Diabetes Therapy. 9, 3, p. 1217-1232 16 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Costs and Cost Analysis
Quality-Adjusted Life Years
Cost Savings
Risk Reduction Behavior
1 Citations

Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): The DERIVE Study

On Behalf of the DERIVE Study Investigators, Jan 1 2018, (Accepted/In press) In : Diabetes, Obesity and Metabolism. 20, 11, p. 2532-2540 9 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Kidney
Safety
Placebos
11 Citations

Efficacy and safety of ITCA 650, a novel drug-Device GLP-1 receptor agonist, in type 2 diabetes uncontrolled with oral antidiabetes drugs: The FREEDOM-1 trial

Rosenstock, J., Buse, J. B., Azeem, R., Prabhakar, P., Kjems, L., Huang, H. & Baron, M. A., Feb 1 2018, In : Diabetes care. 41, 2, p. 333-340 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Safety
Equipment and Supplies
Placebos
Pharmaceutical Preparations
2 Citations

Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes

MetGen Investigators & ACCORD/ACCORDion Investigators, Jul 1 2018, In : Diabetes. 67, 7, p. 1428-1440 13 p.

Research output: Contribution to journalArticle

Metformin
Type 2 Diabetes Mellitus
Glucose
Feeding Behavior
Knockout Mice
3 Citations

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes

The ACCORD/ACCORDion Investigators, Apr 1 2018, In : Clinical pharmacology and therapeutics. 103, 4, p. 712-721 10 p.

Research output: Contribution to journalArticle

Fenofibrate
Type 2 Diabetes Mellitus
Dyslipidemias
Lipids
Gene Expression

Homeostasis model assessment of insulin resistance and survival in patients with diabetes and acute coronary syndrome

Stähli, B. E., Nozza, A., Schrieks, I. C., Buse, J. B., Malmberg, K., Mellbin, L., Neal, B., Nicholls, S. J., Rydén, L., Svensson, A., Wedel, H., Weichert, A., Lincoff, A. M., Grobbee, D. E., Tardif, J. C. & Schwartz, G. G., Jul 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2522-2533 12 p.

Research output: Contribution to journalArticle

Acute Coronary Syndrome
Insulin Resistance
Homeostasis
Type 2 Diabetes Mellitus
Survival
1 Citations

Increased risk of severe hypoglycemic events before and after cardiovascular outcomes in TECOSSuggests an at-risk type 2 diabetes frail patient phenotype

Standl, E., Stevens, S. R., Armstrong, P. W., Buse, J. B., Chan, J. C. N., Green, J. B., Lachin, J. M., Scheen, A., Travert, F., Van De Werf, F., Peterson, E. D. & Holman, R. R., Mar 1 2018, In : Diabetes Care. 41, 3, p. 596-603 8 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Type 2 Diabetes Mellitus
Phenotype
Hospitalization
Heart Failure
Type 2 Diabetes Mellitus
Costs and Cost Analysis
Hospitalization
Placebos
Outpatients

Management of type 1 diabetes with a very low–Carbohydrate diet: A word of caution

Mayer-Davis, E. J., Laffel, L. M. & Buse, J. B., Aug 1 2018, In : Pediatrics. 142, 2, e20181536B

Research output: Contribution to journalLetter

Carbohydrate-Restricted Diet
Type 1 Diabetes Mellitus
2 Citations

Modulation of GLP-1 levels by a genetic variant that regulates the cardiovascular effects of intensive glycemic control in ACCORD

Shah, H. S., Morieri, M. L., Marcovina, S. M., Sigal, R. J., Gerstein, H. C., Wagner, M. J., Motsinger-Reif, A. A., Buse, J. B., Kraft, P., Mychaleckyj, J. C. & Doria, A., Feb 1 2018, In : Diabetes care. 41, 2, p. 348-355 8 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Homozygote
Linear Models
Biomarkers
Mortality

Myocardial Infarction Subtypes in Patients With Type 2 Diabetes Mellitus and the Effect of Liraglutide Therapy (from the LEADER Trial)

LEADER Publication Committee on behalf of the LEADER Trial Investigators, Jun 15 2018, In : American Journal of Cardiology. 121, 12, p. 1467-1470 4 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Myocardial Infarction
Placebos
Therapeutics
Troponin

Primum Non Nocere: Refocusing Our Attention on Severe Hypoglycemia Prevention

Kahkoska, A. R. & Buse, J. B., Aug 1 2018, In : Diabetes Care. 41, 8, p. 1557-1559 3 p.

Research output: Contribution to journalComment/debate

Hypoglycemia
13 Citations

Synthetic beta cells for fusion-mediated dynamic insulin secretion

Chen, Z., Wang, J., Sun, W., Archibong, E., Kahkoska, A. R., Zhang, X., Lu, Y., Ligler, F. S., Buse, J. B. & Gu, Z., Jan 1 2018, In : Nature Chemical Biology. 14, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

Biomimetic Materials
Cell Engineering
Artificial Cells
Membrane Fusion
Experimental Diabetes Mellitus
Dipeptidyl-Peptidase IV Inhibitors
Pancreatitis
Cardiovascular Diseases
Pancreatic Diseases
Medicare
2017
7 Citations

Amylase, lipase, and acute pancreatitis in people with type 2 diabetes treatedwith liraglutide: Results from the LEADER randomized trial

the LEADER Steering Committee, on behalf of the LEADER Trial Investigators, Jul 1 2017, In : Diabetes care. 40, 7, p. 966-972 7 p.

Research output: Contribution to journalArticle

Amylases
Lipase
Pancreatitis
Type 2 Diabetes Mellitus
Placebos
22 Citations

Association of fenofibrate therapy with long-term cardiovascular risk in statin-treated patients with type 2 diabetes

ACCORDION Study Investigators, Apr 1 2017, In : JAMA Cardiology. 2, 4, p. 370-380 11 p.

Research output: Contribution to journalArticle

Fenofibrate
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Type 2 Diabetes Mellitus
Cardiovascular Diseases
HDL Cholesterol
11 Citations

Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

Mentz, R. J., Bethel, M. A., Gustavson, S., Thompson, V. P., Pagidipati, N. J., Buse, J. B., Chan, J. C., Iqbal, N., Maggioni, A. P., Marso, S. P., Ohman, P., Poulter, N., Ramachandran, A., Zinman, B., Hernandez, A. F. & Holman, R. R., May 1 2017, In : American heart journal. 187, p. 1-9 9 p.

Research output: Contribution to journalArticle

Placebos
Dipeptidyl-Peptidase IV Inhibitors
Cerebrovascular Disorders
Latin America
Peripheral Arterial Disease

Causes of death in a contemporary cohort of patients with type 2 diabetes and atherosclerotic cardiovascular disease: Insights from the TECOS trial

TECOS Study Group, Dec 1 2017, In : Diabetes care. 40, 12, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

Proportional Hazards Models
Double-Blind Method
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Cause of Death
3 Citations

Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial

The ACCORD/ACCORDion Investigators, Jan 1 2017, In : PeerJ. 2017, 5, e3187

Research output: Contribution to journalArticle

Water recycling
Exome
Genomics
Genetic Markers
noninsulin-dependent diabetes mellitus

Differential Use of Screening Mammography in Older Women Initiating Metformin versus Sulfonylurea

Hong, J. L., Henderson, L. M., Jonsson Funk, M., Lund, J. L., Buse, J. B., Pate, V. & Stürmer, T., Jun 1 2017, In : Pharmacoepidemiology and drug safety. 26, 6, p. 666-675 10 p.

Research output: Contribution to journalArticle

Metformin
Mammography
Breast Neoplasms
Incidence
Medicare
166 Citations

Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

EXSCEL Study Group, Sep 28 2017, In : New England Journal of Medicine. 377, 13, p. 1228-1239 12 p.

Research output: Contribution to journalArticle

43 Citations

Effects of sotagliflozin added to insulin in patients with type 1 diabetes

Garg, S. K., Henry, R. R., Banks, P., Buse, J. B., Davies, M. J., Fulcher, G. R., Pozzilli, P., Gesty-Palmer, D., Lapuerta, P., Simó, R., Danne, T., McGuire, D. K., Kushner, J. A., Peters, A. & Strumph, P., Dec 14 2017, In : New England Journal of Medicine. 377, 24, p. 2337-2348 12 p.

Research output: Contribution to journalArticle

Sodium-Glucose Transport Proteins
Diabetic Ketoacidosis
Intention to Treat Analysis
Glycosides
Combination Drug Therapy
96 Citations

Efficacy and safety of degludec versus Glargine in Type 2 Diabetes

Marso, S. P., Mcguire, D. K., Zinman, B., Poulter, N. R., Emerson, S. S., Pieber, T. R., Pratley, R. E., Haahr, P. M., Lange, M., Brown-Frandsen, K., Moses, A., Skibsted, S., Kvist, K. & Buse, J. B., Aug 24 2017, In : New England Journal of Medicine. 377, 8, p. 723-732 10 p.

Research output: Contribution to journalArticle

Long-Acting Insulin
Kaplan-Meier Estimate
Hypoglycemia
Double-Blind Method
Hypoglycemic Agents
20 Citations

Glucose self-monitoring in non-insulin-treated patients with type 2 diabetes in primary care settings: A randomized trial

Young, L. A., Buse, J. B., Weaver, M. A., Vu, M. B., Mitchell, C. M., Blakeney, T., Grimm, K., Rees, J., Niblock, F. & Donahue, K. E., Jul 1 2017, In : JAMA internal medicine. 177, 7, p. 920-929 10 p.

Research output: Contribution to journalArticle

Outcome and Process Assessment (Health Care)
Blood Glucose Self-Monitoring
Disease Management
Hypoglycemic Agents
Type 2 Diabetes Mellitus
47 Citations

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery

Hu, X., Yu, J., Qian, C., Lu, Y., Kahkoska, A. R., Xie, Z., Jing, X., Buse, J. B. & Gu, Z., Jan 24 2017, In : ACS Nano. 11, 1, p. 613-620 8 p.

Research output: Contribution to journalArticle

4 Citations

Hypertension Control in Adults with Diabetes Mellitus and Recurrent Cardiovascular Events: Global Results from the Trial Evaluating Cardiovascular Outcomes with Sitagliptin

Navar, A. M., Gallup, D. S., Lokhnygina, Y., Green, J. B., McGuire, D. K., Armstrong, P. W., Buse, J. B., Engel, S. S., Lachin, J. M., Standl, E., Van De Werf, F., Holman, R. R. & Peterson, E. D., Nov 1 2017, In : Hypertension. 70, 5, p. 907-914 8 p.

Research output: Contribution to journalArticle

50 Citations

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

Yu, J., Qian, C., Zhang, Y., Cui, Z., Zhu, Y., Shen, Q., Ligler, F. S., Buse, J. B. & Gu, Z., Feb 8 2017, In : Nano Letters. 17, 2, p. 733-739 7 p.

Research output: Contribution to journalArticle

insulin
Insulin
hypoxia
glucose
Glucose

In reply

Young, L. A., Buse, J. B. & Donahue, K. E., Dec 1 2017, In : JAMA internal medicine. 177, 12, p. 1874-1875 2 p.

Research output: Contribution to journalLetter

5 Citations

Insulin-Responsive Glucagon Delivery for Prevention of Hypoglycemia

Yu, J., Zhang, Y., Sun, W., Kahkoska, A. R., Wang, J., Buse, J. B. & Gu, Z., May 17 2017, In : Small. 13, 19, 1603028

Research output: Contribution to journalArticle

Insulin
Glucagon
Hypoglycemia
Needles
Glucose
96 Citations

Liraglutide and renal outcomes in type 2 diabetes

LEADER Steering Committee and Investigators, Aug 31 2017, In : New England Journal of Medicine. 377, 9, p. 839-848 10 p.

Research output: Contribution to journalArticle

Intention to Treat Analysis
Glucagon-Like Peptide 1
Albuminuria
Diabetic Nephropathies
Glomerular Filtration Rate
7 Citations

Metformin use may moderate the effect of DPP-4 inhibitors on cardiovascular outcomes

Crowley, M. J., Williams, J. W., Kosinski, A. S., D'Alessio, D. A. & Buse, J. B., Dec 1 2017, In : Diabetes care. 40, 12, p. 1787-1789 3 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Metformin
Drug Interactions
Proportional Hazards Models
Type 2 Diabetes Mellitus
7 Citations
Dipeptidyl-Peptidase IV Inhibitors
Incretins
Hypoglycemic Agents
Observational Studies
Thiazolidinediones
17 Citations

Pancreatic safety of sitagliptin in the TECOS study

for the TECOS Study Group, Feb 1 2017, In : Diabetes care. 40, 2, p. 164-170 7 p.

Research output: Contribution to journalArticle

Pancreatitis
Pancreatic Neoplasms
Safety
Dipeptidyl-Peptidase IV Inhibitors
Placebos
23 Citations

Red Blood Cells for Glucose-Responsive Insulin Delivery

Wang, C., Ye, Y., Sun, W., Yu, J., Wang, J., Lawrence, D. S., Buse, J. B. & Gu, Z., May 10 2017, In : Advanced Materials. 29, 18, 1606617

Research output: Contribution to journalArticle

Insulin
Glucose
Blood
Cells
Cell membranes
1 Citations

Safety of degludec versus glargine in type 2 diabetes

Marso, S. P. & Buse, J. B., Nov 16 2017, In : New England Journal of Medicine. 377, 20, p. 1995-1996 2 p.

Research output: Contribution to journalLetter

Type 2 Diabetes Mellitus
Safety
Insulin Glargine
insulin degludec
18 Citations

Sitagliptin and risk of fractures in type 2 diabetes: Results from the TECOS trial

on behalf of the TECOS Study Group, Jan 1 2017, In : Diabetes, Obesity and Metabolism. 19, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Osteoporotic Fractures
Metformin
Confidence Intervals
Odds Ratio
6 Citations

Sodium-glucose cotransporter 2 inhibitors and diabetic ketoacidosis: A case series from three academic institutions

Misaghian-Xanthos, N., Shariff, A. I., Mekala, K., Fearrington, L. R., Setji, T. L., Aloi, J. A. & Buse, J. B., Jun 1 2017, In : Diabetes care. 40, 6, p. e65-e66

Research output: Contribution to journalShort survey

The war is not yet won

Young, L. A. & Buse, J. B., Sep 1 2017, In : Diabetes Care. 40, 9, p. 1152-1153 2 p.

Research output: Contribution to journalComment/debate

Warfare
1 Citations

Three approaches to glucose monitoring in non-insulin treated diabetes: A pragmatic randomized clinical trial protocol

Young, L. A., Buse, J. B., Weaver, M. A., Vu, M. B., Reese, A., Mitchell, C. M., Blakeney, T., Grimm, K., Rees, J. & Donahue, K. E., May 25 2017, In : BMC health services research. 17, 1, 369

Research output: Contribution to journalArticle

Pragmatic Clinical Trials
Blood Glucose Self-Monitoring
Clinical Protocols
Type 2 Diabetes Mellitus
Randomized Controlled Trials

Update and next steps for real-world translation of interventions for type 2 diabetes prevention: Reflections from a diabetes care editors' expert forum. Diabetes care 2016;39:1186-1201

Cefalu, W. T., Buse, J. B., Tuomilehto, J., Fleming, G. A., Ferrannini, E., Gerstein, H. C., Bennett, P. H., Ramachandran, A., Raz, I., Rosenstock, J. & Kahn, S. E., Feb 1 2017, In : Diabetes care. 40, 2, p. e23-e24

Research output: Contribution to journalComment/debate

2016
83 Citations

Association between sitagliptin use and heart failure hospitalization and related outcomes in type 2 diabetes mellitus: Secondary analysis of a randomized clinical trial

McGuire, D. K., Van De Werf, F., Armstrong, P. W., Standl, E., Koglin, J., Green, J. B., Bethel, M. A., Cornel, J. H., Lopes, R. D., Halvorsen, S., Ambrosio, G., Buse, J. B., Josse, R. G., Lachin, J. M., Pencina, M. J., Garg, J., Lokhnygina, Y., Holman, R. R. & Peterson, E. D., May 1 2016, In : JAMA Cardiology. 1, 2, p. 126-135 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Hospitalization
Randomized Controlled Trials
Heart Failure
Placebos