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2018
1 Citations

A Bayesian hierarchical model for network meta-analysis of multiple diagnostic tests

Ma, X., Lian, Q., Chu, H., Ibrahim, J. G. & Chen, Y., Jan 1 2018, In : Biostatistics. 19, 1, p. 87-102 16 p.

Research output: Contribution to journalArticle

Bayesian Hierarchical Model
Multiple Tests
Diagnostic Tests
Hierarchical Model
Missing Data

A practical Bayesian adaptive design incorporating data from historical controls

Psioda, M. A., Soukup, M. & Ibrahim, J. G., Jan 1 2018, (Accepted/In press) In : Statistics in Medicine.

Research output: Contribution to journalArticle

Bayesian Design
Adaptive Design
Linear Models
Linear Regression Model
Statistical Models

Biomarker threshold adaptive designs for survival endpoints

Diao, G., Dong, J., Zeng, D., Ke, C., Rong, A. & Ibrahim, J. G., Feb 14 2018, (Accepted/In press) In : Journal of Biopharmaceutical Statistics. p. 1-17 17 p.

Research output: Contribution to journalArticle

Two-stage Design
Adaptive Design
Biomarkers
Survival
Subgroup
1 Citations

Effect of grass sublingual tablet immunotherapy is similar in children and adults: A Bayesian approach to design pediatric sublingual immunotherapy trials

Kaur, A., Skoner, D., Ibrahim, J., Li, Q., Lockey, R. F., Blaiss, M., Bufe, A., Andersen, J. S., Canonica, G. W. & Nolte, H., May 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 5, p. 1744-1749 6 p.

Research output: Contribution to journalArticle

Sublingual Immunotherapy
Bayes Theorem
Poaceae
Tablets
Phleum

Estimating Treatment Effects for Recurrent Events in the Presence of Rescue Medications: An Application to the Immune Thrombocytopenia Study

Gao, F., Zeng, D., Wei, H., Wang, X. & Ibrahim, J. G., Aug 1 2018, In : Statistics in Biosciences. 10, 2, p. 473-489 17 p.

Research output: Contribution to journalArticle

Recurrent Events
Idiopathic Thrombocytopenic Purpura
Treatment Effects
Platelets
Hemorrhage

FLCRM: Functional linear cox regression model

Kong, D., Ibrahim, J. G., Lee, E. & Zhu, H., Mar 1 2018, In : Biometrics. 74, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

Cox Regression Model
Linear Regression Model
Proportional Hazards Models
Linear regression
Neuroimaging

MILFM: Multiple index latent factor model based on high-dimensional features

Yang, H., Zhu, H. & Ibrahim, J. G., Sep 1 2018, In : Biometrics. 74, 3, p. 834-844 11 p.

Research output: Contribution to journalArticle

Factor Models
High-dimensional
Model-based
Modeling
Prediction Model

Semiparametric regression analysis for composite endpoints subject to componentwise censoring

Diao, G., Zeng, D., Ke, C., Ma, H., Jiang, Q. & Ibrahim, J. G., Jun 1 2018, In : Biometrika. 105, 2, p. 403-418 16 p.

Research output: Contribution to journalArticle

Semiparametric Regression
Censoring
endpoints
Progression
Regression Analysis
2017

Bayesian clinical trial design using Markov models with applications to autoimmune disease

Eggleston, B. S., Ibrahim, J. G. & Catellier, D., Dec 1 2017, In : Contemporary Clinical Trials. 63, p. 73-83 11 p.

Research output: Contribution to journalArticle

Platelet Count
Autoimmune Diseases
Clinical Trials
Hemorrhage
Recurrence
2 Citations

Bayesian longitudinal low-rank regression models for imaging genetic data from longitudinal studies

Lu, Z. H., Khondker, Z., Ibrahim, J. G., Wang, Y. & Zhu, H., Apr 1 2017, In : NeuroImage. 149, p. 305-322 18 p.

Research output: Contribution to journalArticle

Genetic Models
Longitudinal Studies
Neuroimaging
Single Nucleotide Polymorphism
Alzheimer Disease
2 Citations

Bayesian Model Assessment in Joint Modeling of Longitudinal and Survival Data With Applications to Cancer Clinical Trials

Zhang, D., Chen, M. H., Ibrahim, J. G., Boye, M. E. & Shen, W., Jan 2 2017, In : Journal of Computational and Graphical Statistics. 26, 1, p. 121-133 13 p.

Research output: Contribution to journalArticle

Joint Modeling
Joint Model
Survival Data
Bayesian Model
Longitudinal Data
4 Citations

Comprehensive assessment of cytochromes P450 and transporter genetics with endoxifen concentration during tamoxifen treatment

Marcath, L. A., Deal, A. M., Van Wieren, E., Danko, W., Walko, C. M., Ibrahim, J. G., Weck, K. E., Jones, D. R., Desta, Z., McLeod, H. L., Carey, L. A., Irvin, W. J. & Hertz, D. L., Jan 1 2017, In : Pharmacogenetics and Genomics. 27, 11, p. 402-409 8 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Pharmacogenetics
Tamoxifen
Cytochrome P-450 Enzyme System
Enzymes

Control-based imputation for sensitivity analyses in informative censoring for recurrent event data

Gao, F., Liu, G. F., Zeng, D., Xu, L., Lin, B., Diao, G., Golm, G., Heyse, J. F. & Ibrahim, J. G., Nov 1 2017, In : Pharmaceutical statistics. 16, 6, p. 424-432 9 p.

Research output: Contribution to journalArticle

Informative Censoring
Recurrent Events
Multiple Imputation
Imputation
Missing Data

HFPRM: Hierarchical functional principal regression model for diffusion tensor image bundle statistics

Zhang, J., Huang, C., Ibrahim, J. G., Jha, S., Knickmeyer, R. C., Gilmore, J. H., Styner, M. & Zhu, H., Jan 1 2017, Information Processing in Medical Imaging - 25th International Conference, IPMI 2017, Proceedings. Zhu, H., Niethammer, M., Styner, M., Zhu, H., Shen, D., Yap, P-T., Aylward, S. & Oguz, I. (eds.). Springer Verlag, p. 478-489 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10265 LNCS)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Functional Principal Component Analysis
Varying Coefficient Model
Magnetic Resonance Imaging
Medical Imaging
Medical imaging
1 Citations

LCN: A random graph mixture model for community detection in functional brain networks

Bryant, C., Zhu, H., Ahn, M. & Ibrahim, J., Jan 1 2017, In : Statistics and its Interface. 10, 3, p. 369-378 10 p.

Research output: Contribution to journalArticle

Latent Class
Community Detection
Community Structure
Graph Model
Mixture Model
Informative Dropout
Semiparametric Efficiency
Nonparametric Maximum Likelihood Estimator
Cox Model
Count Data

On inference of control-based imputation for analysis of repeated binary outcomes with missing data

Gao, F., Liu, G., Zeng, D., Diao, G., Heyse, J. F. & Ibrahim, J. G., May 4 2017, In : Journal of Biopharmaceutical Statistics. 27, 3, p. 358-372 15 p.

Research output: Contribution to journalArticle

Binary Outcomes
Imputation
Missing Data
Clinical Trials
Biased

Pattern mixture models for clinical validation of biomarkers in the presence of missing data

Gao, F., Dong, J., Zeng, D., Rong, A. & Ibrahim, J. G., Aug 30 2017, In : Statistics in medicine. 36, 19, p. 2994-3004 11 p.

Research output: Contribution to journalArticle

Pattern-mixture Model
Biomarkers
Missing Data
Clinical Trials
Therapy
4 Citations

Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells

Bower, J. J., Vance, L. D., Psioda, M., Smith-Roe, S. L., Simpson, D. A., Ibrahim, J. G., Hoadley, K. A., Perou, C. M. & Kaufmann, W. K., Dec 1 2017, In : npj Breast Cancer. 3, 1, 0009

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Breast Neoplasms
M Phase Cell Cycle Checkpoints
Cell Line
Genomic Instability
4 Citations

Regression models on Riemannian symmetric spaces

The Alzheimer's Disease Neuroimaging Initiative, Mar 1 2017, In : Journal of the Royal Statistical Society. Series B: Statistical Methodology. 79, 2, p. 463-482 20 p.

Research output: Contribution to journalArticle

Riemannian Symmetric Space
Regression Model
Test Statistic
Euclidean space
Covariates
3 Citations

Statistical design of noninferiority multiple region clinical trials to assess global and consistent treatment effects

Diao, G., Zeng, D., Ibrahim, J. G., Rong, A., Lee, O., Zhang, K. & Chen, Q., Nov 2 2017, In : Journal of Biopharmaceutical Statistics. 27, 6, p. 933-944 12 p.

Research output: Contribution to journalArticle

Non-inferiority
Treatment Effects
Clinical Trials
Guidelines
Pharmaceutical Preparations
2016
1 Citations

An Automated High-throughput Array Microscope for Cancer Cell Mechanics

Cribb, J. A., Osborne, L. D., Beicker, K., Psioda, M., Chen, J., O'Brien, E. T., Taylor, R. M., Vicci, L., Hsiao, J. P. L., Shao, C., Falvo, M., Ibrahim, J. G., Wood, K. C., Blobe, G. C. & Superfine, R., Jun 6 2016, In : Scientific Reports. 6, 27371

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Mechanics
Compliance
Epithelial Cells
Rheology
1 Citations
Gene expression
Sequencing
Statistical Model
Gene Expression
Polymorphism
3 Citations

Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines

Cordeiro-Stone, M., Mcnulty, J. J., Sproul, C. D., Chastain, P. D., Gibbs-Flournoy, E., Zhou, Y., Carson, C., Rao, S., Mitchell, D. L., Simpson, D. A., Thomas, N. E., Ibrahim, J. G. & Kaufmann, W. K., Jan 1 2016, In : Pigment Cell and Melanoma Research. 29, 1, p. 68-80 13 p.

Research output: Contribution to journalArticle

S Phase Cell Cycle Checkpoints
Melanocytes
Fibroblasts
Melanoma
Cells
4 Citations

JMFit: A SAS macro for joint models of longitudinal and survival data

Zhang, D., Chen, M. H., Ibrahim, J. G., Boye, M. E. & Shen, W., Jan 1 2016, In : Journal of Statistical Software. 71, p. 1-24 24 p.

Research output: Contribution to journalArticle

Joint Model
Survival Data
Longitudinal Data
Macros
Survival Model

Reply to Comments

Zeng, D., Gao, F., Ibrahim, J. G., Hu, K. & Jia, C., Apr 30 2016, In : Statistics in Medicine. 35, 9, p. 1560 1 p.

Research output: Contribution to journalLetter

Sample Size
Human

SR-HARDI: Spatially Regularizing High Angular Resolution Diffusion Imaging

Rao, S., Ibrahim, J. G., Cheng, J., Yap, P. T. & Zhu, H., Oct 1 2016, In : Journal of Computational and Graphical Statistics. 25, 4, p. 1195-1211 17 p.

Research output: Contribution to journalArticle

High Angular Resolution
Regression Model
Imaging
Voxel
Fiber
8 Citations

Tamoxifen dose escalation in patients with diminished CYP2D6 activity normalizes endoxifen concentrations without increasing toxicity

Hertz, D. L. , Deal, A. , Ibrahim, J. G. , Walko, C. M. , Weck, K. E. , Anderson, S. , Magrinat, G. , Olajide, O. , Moore, S. , Raab, R. , Carrizosa, D. R. , Corso, S. , Schwartz, G. , Graham, M. , Peppercorn, J. M. , Jones, D. R. , Desta, Z. , Flockhart, D. A. , Evans, J. P. , McLeod, H. L. & 2 others Carey, L. A. & Irvin, W. J., Jul 1 2016, In : Oncologist. 21, 7, p. 795-803 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Tamoxifen
Breast Neoplasms
Quality of Life
Genotype
2015
1 Citations

A counterfactual P -Value approach for benefit-risk assessment in clinical trials

Zeng, D., Chen, M. H., Ibrahim, J. G., Wei, R., Ding, B., Ke, C. & Jiang, Q., Jan 1 2015, In : Journal of Biopharmaceutical Statistics. 25, 3, p. 508-524 17 p.

Research output: Contribution to journalArticle

Risk Assessment
Clinical Trials
p-Value
Weights and Measures
Efficacy
1 Citations

Bayesian Inference for Multivariate Meta-Regression With a Partially Observed Within-Study Sample Covariance Matrix

Yao, H., Kim, S., Chen, M. H., Ibrahim, J. G., Shah, A. K. & Lin, J., Apr 3 2015, In : Journal of the American Statistical Association. 110, 510, p. 528-544 17 p.

Research output: Contribution to journalArticle

Sample Covariance Matrix
Cholesterol
Bayesian inference
Lipoproteins
Regression
2 Citations

Bayesian probability of success for clinical trials using historical data

Ibrahim, J. G., Chen, M. H., Lakshminarayanan, M., Liu, G. F. & Heyse, J. F., Jan 1 2015, In : Statistics in medicine. 34, 2, p. 249-264 16 p.

Research output: Contribution to journalArticle

Historical Data
Clinical Trials
Covariates
Methodology
Planning
5 Citations

Bflcrm: A bayesian functional linear cox regression model for predicting time to conversion to alzheimer’s disease

Alzheimer’s disease neuroimaging initiative, Dec 1 2015, In : Annals of Applied Statistics. 9, 4, p. 2153-2178 26 p.

Research output: Contribution to journalArticle

Cox Regression Model
Alzheimer's Disease
Linear Regression Model
Linear regression
Covariates
2 Citations

Diagnostic measures for the Cox regression model with missing covariates

Zhu, H., Ibrahim, J. G. & Chen, M. H., Dec 1 2015, In : Biometrika. 102, 4, p. 907-923 17 p.

Research output: Contribution to journalArticle

Martingale Residuals
Cox Regression Model
Missing Covariates
Goodness of fit
Proportional Hazards Models
4 Citations

DNA damage checkpoint responses in the S phase of synchronized diploid human fibroblasts

Chastain, P. D., Brylawski, B. P., Zhou, Y. C., Rao, S., Chu, H., Ibrahim, J. G., Kaufmann, W. K. & Cordeiro-Stone, M., Jan 1 2015, In : Photochemistry and Photobiology. 91, 1, p. 109-116 8 p.

Research output: Contribution to journalArticle

fibroblasts
Fibroblasts
Diploidy
S Phase
DNA Damage

Homology cluster differential expression analysis for interspecies mRNA-Seq experiments

Gelfond, J. A., Ibrahim, J. G., Chen, M. H., Sun, W., Lewis, K., Kinahan, S., Hibbs, M. & Buffenstein, R., Dec 1 2015, In : Statistical Applications in Genetics and Molecular Biology. 14, 6, p. 507-516 10 p.

Research output: Contribution to journalArticle

Mole Rats
Differential Expression
Transcriptome
Messenger RNA
Rats
5 Citations

Hypothesis testing for two-stage designs with over or under enrollment

Zeng, D., Gao, F., Hu, K., Jia, C. & Ibrahim, J. G., Jul 20 2015, In : Statistics in Medicine. 34, 16, p. 2417-2426 10 p.

Research output: Contribution to journalArticle

Two-stage Design
Hypothesis Testing
Sample Size
Type I error
Normal Approximation
6 Citations

Identifiability of PBPK models with applications to dimethylarsinic acid exposure

Garcia, R. I., Ibrahim, J. G., Wambaugh, J. F., Kenyon, E. M. & Setzer, R. W., Jul 21 2015, In : Journal of Pharmacokinetics and Pharmacodynamics. 42, 6, p. 591-609 19 p.

Research output: Contribution to journalArticle

Cacodylic Acid
Pharmacokinetics
Statistical Models
Bayes Theorem
16 Citations

In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles

Hertz, D. L. , Snavely, A. C. , McLeod, H. L. , Walko, C. M. , Ibrahim, J. G. , Anderson, S. , Weck, K. E. , Magrinat, G. , Olajide, O. , Moore, S. , Raab, R. , Carrizosa, D. R. , Corso, S. , Schwartz, G. , Peppercorn, J. M. , Evans, J. P. , Jones, D. R. , Desta, Z. , Flockhart, D. A. , Carey, L. A. & 1 others Irvin, W. J., Nov 1 2015, In : British Journal of Clinical Pharmacology. 80, 5, p. 1122-1130 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Alleles
Tamoxifen
Phenotype
Genotype
29 Citations

Joint modeling of survival and longitudinal non-survival data: Current methods and issues. Report of the DIA Bayesian joint modeling working group

Lawrence Gould, A., Boye, M. E., Crowther, M. J., Ibrahim, J. G., Quartey, G., Micallef, S. & Bois, F. Y., Jan 1 2015, In : Statistics in Medicine. 34, 14, p. 2181-2195 15 p.

Research output: Contribution to journalArticle

Joint Modeling
Bayesian Modeling
Bayes Theorem
Software
Joints

Quantifying the average of the time-varying hazard ratio via a class of transformations

Chen, Q., Zeng, D., Ibrahim, J. G., Chen, M. H., Pan, Z. & Xue, X., 2015, In : Lifetime Data Analysis. 21, 2, p. 259-279 21 p.

Research output: Contribution to journalArticle

Hazard
Time-varying
Hazards
Proportional Hazards Models
Cox Model
4 Citations

Responses to discussants of 'Joint modeling of survival and longitudinal non-survival data: Current methods and issues. report of the DIA Bayesian joint modeling working group'

Gould, A. L., Boye, M. E., Crowther, M. J., Ibrahim, J. G., Quartey, G., Micallef, S. & Bois, F. Y., Jun 30 2015, In : Statistics in Medicine. 34, 14, p. 2202-2203 2 p.

Research output: Contribution to journalComment/debate

Epidemiologic Research Design
Joint Modeling
Bayesian Modeling
Survival Analysis
Statistical Models
7 Citations

SPReM: Sparse Projection Regression Model For High-Dimensional Linear Regression

Sun, Q., Zhu, H., Liu, Y. & Ibrahim, J. G., Jan 2 2015, In : Journal of the American Statistical Association. 110, 509, p. 289-302 14 p.

Research output: Contribution to journalArticle

Linear regression
Regression Model
High-dimensional
Regression
Projection
15 Citations

The power prior: Theory and applications

Ibrahim, J. G., Chen, M. H., Gwon, Y. & Chen, F., Dec 10 2015, In : Statistics in medicine. 34, 28, p. 3724-3749 26 p.

Research output: Contribution to journalArticle

Experimental design
Clinical Trials
Bayesian Design
Conjugate prior
Hierarchical Modeling
2 Citations

The use of bayesian hierarchical models for adaptive randomization in biomarker-driven phase II studies

Barry, W. T., Perou, C. M., Marcom, P. K., Carey, L. A. & Ibrahim, J. G., Jan 1 2015, In : Journal of Biopharmaceutical Statistics. 25, 1, p. 66-88 23 p.

Research output: Contribution to journalArticle

Bayesian Hierarchical Model
Biomarkers
Random Allocation
Randomisation
Nested Design
2014
16 Citations

A community-based multicenter trial of pharmacokinetically guided 5-fluorouracil dosing for personalized colorectal cancer therapy

Patel, J. N., O'neil, B. H., Deal, A. M., Ibrahim, J. G., Sherrill, G. B., Olajide, O. A., Atluri, P. M., Inzerillo, J. J., Chay, C. H., McLeod, H. L. & Walko, C. M., Jan 1 2014, In : Oncologist. 19, 9, p. 959-965 7 p.

Research output: Contribution to journalArticle

Fluorouracil
Multicenter Studies
Colorectal Neoplasms
Odds Ratio
Therapeutics
7 Citations

Assessing model fit in joint models of longitudinal and survival data with applications to cancer clinical trials

Zhang, D., Chen, M. H., Ibrahim, J. G., Boye, M. E., Wang, P. & Shen, W., Jan 1 2014, In : Statistics in medicine. 33, 27, p. 4715-4733 19 p.

Research output: Contribution to journalArticle

imidazole mustard
Joint Model
Survival Data
Longitudinal Data
Clinical Trials
1 Citations

Assessing temporal agreement between central and local progression-free survival times

Zeng, D., Cornea, E., Dong, J., Pan, J. & Ibrahim, J. G., Feb 28 2014, In : Statistics in Medicine. 34, 5, p. 844-858 15 p.

Research output: Contribution to journalArticle

Survival Time
Progression
Disease-Free Survival
Censoring
Clinical Trials
1 Citations

Bayesian case-deletion model complexity and information criterion

Zhu, H., Ibrahim, J. G. & Chen, Q., Jan 1 2014, In : Statistics and its Interface. 7, 4, p. 531-542 12 p.

Research output: Contribution to journalArticle

Case Deletion
Model Complexity
Information Criterion
Deviance Information Criterion
Deviance
2 Citations

Bayesian design of superiority clinical trials for recurrent events data with applications to bleeding and transfusion events in myelodyplastic syndrome

Chen, M. H., Ibrahim, J. G., Zeng, D., Hu, K. & Jia, C., Jan 1 2014, In : Biometrics. 70, 4, p. 1003-1013 11 p.

Research output: Contribution to journalArticle

Bayesian Design
Recurrent Events
Myelodysplastic Syndromes
Clinical Trials
hemorrhage