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2018

Adiponectin, free fatty acids, and cardiovascular outcomes in patients with type 2 diabetes and acute coronary syndrome

Schrieks, I. C., Nozza, A., Stähli, B. E., Buse, J. B., Henry, R. R., Malmberg, K., Neal, B., Nicholls, S. J., Rydén, L., Mellbin, L., Svensson, A., Wedel, H., Weichert, A., Lincoff, A. M., Tardif, J. C., Grobbee, D. E. & Schwartz, G. G., Aug 1 2018, In : Diabetes care. 41, 8, p. 1792-1800 9 p.

Research output: Contribution to journalArticle

Adiponectin
Acute Coronary Syndrome
Nonesterified Fatty Acids
Type 2 Diabetes Mellitus
Coronary Disease
6 Citations

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery

Zhang, Y., Wang, J., Yu, J., Wen, D., Kahkoska, A. R., Lu, Y., Zhang, X., Buse, J. B. & Gu, Z., Apr 5 2018, In : Small. 14, 14, 1704181.

Research output: Contribution to journalArticle

Controlled drug delivery
Glucose sensors
Glucose Oxidase
Medical problems
Drug delivery
Dipeptidyl-Peptidase IV Inhibitors
Hypoglycemic Agents
Thiazolidinediones
Heart Failure
Propensity Score

Can we RISE to the challenge of youth-onset type 2 diabetes?

Buse, J. B., D'Alessio, D. A. & Riddle, M. C., Aug 1 2018, In : Diabetes care. 41, 8, p. 1560-1562 3 p.

Research output: Contribution to journalComment/debate

Type 1 Diabetes Mellitus
Age of Onset
Type 2 Diabetes Mellitus
17 Citations

Cardiovascular outcomes trials in type 2 diabetes: Where Do We Go From Here? Ref lections From a Diabetes Care Editors' Expert Forum

Cefalu, W. T., Kaul, S., Gerstein, H. C., Holman, R. R., Zinman, B., Skyler, J. S., Green, J. B., Buse, J. B., Inzucchi, S. E., Leiter, L. A., Raz, I., Rosenstock, J. & Riddle, M. C., Jan 1 2018, In : Diabetes care. 41, 1, p. 14-31 18 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Drug Approval
Drug Industry
United States Food and Drug Administration
Pharmaceutical Preparations
42 Citations

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis

EXSCEL Study Group, Feb 1 2018, (Accepted/In press) In : The Lancet Diabetes and Endocrinology. p. 105-113 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Meta-Analysis
Mortality
Safety
Pharmaceutical Preparations
3 Citations
pioglitazone
Dipeptidyl-Peptidase IV Inhibitors
Urinary Bladder Neoplasms
Type 2 Diabetes Mellitus
Safety
4 Citations

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Wang, J., Ye, Y., Yu, J., Kahkoska, A. R., Zhang, X., Wang, C., Sun, W., Corder, R. D., Chen, Z., Khan, S. A., Buse, J. B. & Gu, Z., Mar 27 2018, In : ACS Nano. 12, 3, p. 2466-2473 8 p.

Research output: Contribution to journalArticle

Cytology
Controlled drug delivery
Hydrogels
Hydrogel
Medical problems
24 Citations

Day-to-day fasting glycaemic variability in DEVOTE: associations with severe hypoglycaemia and cardiovascular outcomes (DEVOTE 2)

on behalf of the DEVOTE Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Hypoglycemia
Fasting
Breakfast
Blood Glucose
Mortality
9 Citations

DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality

on behalf of the DEVOTE Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

Hypoglycemia
Mortality
Type 2 Diabetes Mellitus
Safety
Hypoglycemic Agents

DEVOTE 5: Evaluating the Short-Term Cost-Utility of Insulin Degludec Versus Insulin Glargine U100 in Basal–Bolus Regimens for Type 2 Diabetes in the UK

on behalf of the DEVOTE Study Group, Jun 1 2018, In : Diabetes Therapy. 9, 3, p. 1217-1232 16 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Costs and Cost Analysis
Quality-Adjusted Life Years
Cost Savings
Risk Reduction Behavior
Type 2 Diabetes Mellitus
Mortality
Glomerular Filtration Rate
Hemoglobins
Therapeutics
2 Citations

Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): The DERIVE Study

On Behalf of the DERIVE Study Investigators, Nov 1 2018, In : Diabetes, Obesity and Metabolism. 20, 11, p. 2532-2540 9 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Kidney
Safety
Placebos
11 Citations

Efficacy and safety of ITCA 650, a novel drug-Device GLP-1 receptor agonist, in type 2 diabetes uncontrolled with oral antidiabetes drugs: The FREEDOM-1 trial

Rosenstock, J., Buse, J. B., Azeem, R., Prabhakar, P., Kjems, L., Huang, H. & Baron, M. A., Feb 1 2018, In : Diabetes care. 41, 2, p. 333-340 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Safety
Equipment and Supplies
Placebos
Pharmaceutical Preparations

Fast-acting insulin aspart versus insulin aspart in the setting of insulin degludec-treated type 1 diabetes: Efficacy and safety from a randomized double-blind trial

Buse, J. B., Carlson, A. L., Komatsu, M., Mosenzon, O., Rose, L., Liang, B., Buchholtz, K., Horio, H. & Kadowaki, T., Jan 1 2018, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Insulin Aspart
Type 1 Diabetes Mellitus
Meals
Safety
insulin degludec

Genetic tools for coronary risk assessment in type 2 diabetes: A cohort study from the ACCORD clinical trial

Morieri, M. L., Gao, H., Pigeyre, M., Shah, H. S., Sjaarda, J., Mendonca, C., Hastings, T., Buranasupkajorn, P., Motsinger-Reif, A. A., Rotroff, D. M., Sigal, R. J., Marcovina, S. M., Kraft, P., Buse, J. B., Wagner, M. J., Gerstein, H. C., Mychaleckyj, J. C., Parè, G. & Doria, A., Nov 1 2018, In : Diabetes care. 41, 11, p. 2404-2413 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Cohort Studies
Clinical Trials
Coronary Artery Disease
Population
2 Citations

Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes

MetGen Investigators & ACCORD/ACCORDion Investigators, Jul 1 2018, In : Diabetes. 67, 7, p. 1428-1440 13 p.

Research output: Contribution to journalArticle

Metformin
Type 2 Diabetes Mellitus
Glucose
Feeding Behavior
Knockout Mice
5 Citations

Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes

The ACCORD/ACCORDion Investigators, Apr 1 2018, In : Clinical pharmacology and therapeutics. 103, 4, p. 712-721 10 p.

Research output: Contribution to journalArticle

Fenofibrate
Type 2 Diabetes Mellitus
Dyslipidemias
Lipids
Gene Expression

Health literacy, glycemic control, and physician-advised glucose self-monitoring use in type 2 diabetes

Alvarez, P. M., Young, L. A., Mitchell, M., Blakeney, T. G., Buse, J. B., Vu, M. B., Weaver, M. A., Rees, J., Grimm, K. & Donahue, K. E., Nov 1 2018, In : Diabetes Spectrum. 31, 4, p. 344-347 4 p.

Research output: Contribution to journalArticle

Health Literacy
Blood Glucose Self-Monitoring
Type 2 Diabetes Mellitus
Physicians
Glucose

Health-related quality of life in people with type 2 diabetes participating in the LEADER trial

LEADER Publication Committee for the LEADER Trial Investigators, Jan 1 2018, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Placebos
Quality of Life
Visual Analog Scale
Confidence Intervals

Homeostasis model assessment of insulin resistance and survival in patients with diabetes and acute coronary syndrome

Stähli, B. E., Nozza, A., Schrieks, I. C., Buse, J. B., Malmberg, K., Mellbin, L., Neal, B., Nicholls, S. J., Rydén, L., Svensson, A., Wedel, H., Weichert, A., Lincoff, A. M., Grobbee, D. E., Tardif, J. C. & Schwartz, G. G., Jul 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2522-2533 12 p.

Research output: Contribution to journalArticle

Medical problems
Insulin
Brain Natriuretic Peptide
Hazards
PPAR alpha

Hypoglycemia, cardiovascular outcomes, and death: The LEADER experience

Zinman, B., Marso, S. P., Christiansen, E., Calanna, S., Rasmussen, S. & Buse, J. B., Aug 1 2018, In : Diabetes care. 41, 8, p. 1783-1791 9 p.

Research output: Contribution to journalArticle

Hypoglycemia
Placebos
Cause of Death
Liraglutide
Incidence
2 Citations

Increased risk of severe hypoglycemic events before and after cardiovascular outcomes in TECOSSuggests an at-risk type 2 diabetes frail patient phenotype

Standl, E., Stevens, S. R., Armstrong, P. W., Buse, J. B., Chan, J. C. N., Green, J. B., Lachin, J. M., Scheen, A., Travert, F., Van De Werf, F., Peterson, E. D. & Holman, R. R., Mar 1 2018, In : Diabetes Care. 41, 3, p. 596-603 8 p.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Type 2 Diabetes Mellitus
Phenotype
Hospitalization
Heart Failure

Incretin-based therapies and diabetic retinopathy: Real-world evidence in older U.S. adults

Wang, T., Hong, J. L., Gower, E. W., Pate, V., Garg, S., Buse, J. B. & Stuermer, T. H. R., Sep 1 2018, In : Diabetes care. 41, 9, p. 1998-2009 12 p.

Research output: Contribution to journalArticle

Incretins
Diabetic Retinopathy
Glucagon-Like Peptides
Dipeptidyl-Peptidase IV Inhibitors
Thiazolidinediones

Liraglutide and Glycaemic Outcomes in the LEADER Trial

The LEADER Publication Committee on behalf of the LEADER Trial Investigators, Dec 1 2018, In : Diabetes Therapy. 9, 6, p. 2383-2392 10 p.

Research output: Contribution to journalArticle

Placebos
Insulin
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Language

Liraglutide Reduces Cardiovascular Events and Mortality in Type 2 Diabetes Mellitus Independently of Baseline Low-Density Lipoprotein Cholesterol Levels and Statin Use

Verma, S., Leiter, L. A., Mazer, C. D., Bain, S. C., Buse, J. B., Marso, S., Nauck, M., Zinman, B., Bosch-Traberg, H., Rasmussen, S., Michelsen, M. M. & Bhatt, D. L., Oct 9 2018, In : Circulation. 138, 15, p. 1605-1607 3 p.

Research output: Contribution to journalLetter

Hydroxymethylglutaryl-CoA Reductase Inhibitors
LDL Cholesterol
Type 2 Diabetes Mellitus
Diabetes Mellitus
Mortality
Type 2 Diabetes Mellitus
Costs and Cost Analysis
Hospitalization
Placebos
Outpatients

Long-term effects of intensive glycemic and blood pressure control and fenofibrate use on kidney outcomes

Mottl, A. K., Buse, J. B., Ismail-Beigi, F., Sigal, R. J., Pedley, C. F., Papademetriou, V., Simmons, D. L., Katz, L., Mychaleckyj, J. C. & Craven, T. E., Jan 1 2018, In : Clinical Journal of the American Society of Nephrology. 13, 11, p. 1693-1702 10 p.

Research output: Contribution to journalArticle

Fenofibrate
Blood Pressure
Kidney
Confidence Intervals
Type 2 Diabetes Mellitus

Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Davies, M. J., D’Alessio, D. A., Fradkin, J., Kernan, W. N., Mathieu, C., Mingrone, G., Rossing, P., Tsapas, A., Wexler, D. J. & Buse, J. B., Jan 1 2018, (Accepted/In press) In : Diabetologia.

Research output: Contribution to journalArticle

Sodium-Glucose Transport Proteins
Hyperglycemia
Type 2 Diabetes Mellitus
Life Style
Consensus

Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the european association for the study of diabetes (EASD)

Davies, M. J., D'Alessio, D. A., Fradkin, J., Kernan, W. N., Mathieu, C., Mingrone, G., Rossing, P., Tsapas, A., Wexler, D. J. & Buse, J. B., Dec 1 2018, In : Diabetes care. 41, 12, p. 2669-2701 33 p.

Research output: Contribution to journalReview article

Sodium-Glucose Transport Proteins
Hyperglycemia
Type 2 Diabetes Mellitus
Life Style
Consensus

Management of type 1 diabetes with a very low–Carbohydrate diet: A word of caution

Mayer-Davis, E. J., Laffel, L. M. & Buse, J. B., Aug 1 2018, In : Pediatrics. 142, 2, e20181536B.

Research output: Contribution to journalLetter

Carbohydrate-Restricted Diet
Type 1 Diabetes Mellitus
2 Citations

Modulation of GLP-1 levels by a genetic variant that regulates the cardiovascular effects of intensive glycemic control in ACCORD

Shah, H. S., Morieri, M. L., Marcovina, S. M., Sigal, R. J., Gerstein, H. C., Wagner, M. J., Motsinger-Reif, A. A., Buse, J. B., Kraft, P., Mychaleckyj, J. C. & Doria, A., Feb 1 2018, In : Diabetes care. 41, 2, p. 348-355 8 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Homozygote
Linear Models
Biomarkers
Mortality
1 Citations

Myocardial Infarction Subtypes in Patients With Type 2 Diabetes Mellitus and the Effect of Liraglutide Therapy (from the LEADER Trial)

LEADER Publication Committee on behalf of the LEADER Trial Investigators, Jun 15 2018, In : American Journal of Cardiology. 121, 12, p. 1467-1470 4 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Myocardial Infarction
Placebos
Therapeutics
Troponin

Neoplasms reported with liraglutide or placebo in people with type 2 diabetes: Results from the LEADER randomized trial

Nauck, M. A., Jensen, T. J., Rosenkilde, C., Calanna, S. & Buse, J. B., Aug 1 2018, In : Diabetes care. 41, 8, p. 1663-1671 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Placebos
Neoplasms
Pancreatic Neoplasms
Liraglutide

Primum non nocere: Refocusing our attention on severe hypoglycemia prevention

Kahkoska, A. R. & Buse, J. B., Aug 1 2018, In : Diabetes care. 41, 8, p. 1557-1559 3 p.

Research output: Contribution to journalComment/debate

Hypoglycemia

Sotagliflozin in combination with optimized insulin therapy in adults with type 1 diabetes: The North American in Tandem1 study

Buse, J. B., Garg, S. K., Rosenstock, J., Bailey, T. S., Banks, P., Bode, B. W., Danne, T., Kushner, J. A., Lane, W. S., Lapuerta, P., McGuire, D. K., Peters, A. L., Reed, J., Sawhney, S. & Strumph, P., Sep 1 2018, In : Diabetes care. 41, 9, p. 1970-1980 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Insulin
Placebos
Therapeutics
Diabetic Ketoacidosis

Strategy for Mitigating DKA Risk in Patients with Type 1 Diabetes on Adjunctive Treatment with SGLT Inhibitors: A STICH Protocol

Garg, S. K., Peters, A. L., Buse, J. B. & Danne, T., Sep 1 2018, In : Diabetes Technology and Therapeutics. 20, 9, p. 572-575 4 p.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Therapeutics
14 Citations

Synthetic beta cells for fusion-mediated dynamic insulin secretion

Chen, Z., Wang, J., Sun, W., Archibong, E., Kahkoska, A. R., Zhang, X., Lu, Y., Ligler, F. S., Buse, J. B. & Gu, Z., Jan 1 2018, In : Nature Chemical Biology. 14, 1, p. 86-93 8 p.

Research output: Contribution to journalArticle

Artificial Cells
Cell Fusion
Insulin
Glucose
Insulin Infusion Systems

The impact of liraglutide on diabetes-related foot ulceration and associated complications in patients with type 2 diabetes at high risk for cardiovascular events: Results from the LEADER trial

LEADER Publication Committee on behalf of the LEADER Trial Investigators, Oct 1 2018, In : Diabetes care. 41, 10, p. 2229-2235 7 p.

Research output: Contribution to journalArticle

Foot Ulcer
Type 2 Diabetes Mellitus
Foot
Placebos
Amputation
Dipeptidyl-Peptidase IV Inhibitors
Pancreatitis
Cardiovascular Diseases
Pancreatic Diseases
Medicare
2017
7 Citations

Amylase, lipase, and acute pancreatitis in people with type 2 diabetes treatedwith liraglutide: Results from the LEADER randomized trial

the LEADER Steering Committee, on behalf of the LEADER Trial Investigators, Jul 1 2017, In : Diabetes care. 40, 7, p. 966-972 7 p.

Research output: Contribution to journalArticle

Amylases
Lipase
Pancreatitis
Type 2 Diabetes Mellitus
Placebos
23 Citations

Association of fenofibrate therapy with long-term cardiovascular risk in statin-treated patients with type 2 diabetes

ACCORDION Study Investigators, Apr 1 2017, In : JAMA Cardiology. 2, 4, p. 370-380 11 p.

Research output: Contribution to journalArticle

Fenofibrate
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Type 2 Diabetes Mellitus
Cardiovascular Diseases
HDL Cholesterol
12 Citations

Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

Mentz, R. J., Bethel, M. A., Gustavson, S., Thompson, V. P., Pagidipati, N. J., Buse, J. B., Chan, J. C., Iqbal, N., Maggioni, A. P., Marso, S. P., Ohman, P., Poulter, N., Ramachandran, A., Zinman, B., Hernandez, A. F. & Holman, R. R., May 1 2017, In : American heart journal. 187, p. 1-9 9 p.

Research output: Contribution to journalArticle

Placebos
Dipeptidyl-Peptidase IV Inhibitors
Cerebrovascular Disorders
Latin America
Peripheral Arterial Disease

Causes of death in a contemporary cohort of patients with type 2 diabetes and atherosclerotic cardiovascular disease: Insights from the TECOS trial

TECOS Study Group, Dec 1 2017, In : Diabetes care. 40, 12, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Cause of Death
Cardiovascular Diseases
Heart Failure
Sudden Death
3 Citations

Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial

The ACCORD/ACCORDion Investigators, Jan 1 2017, In : PeerJ. 2017, 5, e3187.

Research output: Contribution to journalArticle

Medical problems
Genetic Markers
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
clinical trials

Differential Use of Screening Mammography in Older Women Initiating Metformin versus Sulfonylurea

Hong, J. L., Henderson, L. M., Jonsson Funk, M., Lund, J. L., Buse, J. B., Pate, V. & Stürmer, T., Jun 1 2017, In : Pharmacoepidemiology and drug safety. 26, 6, p. 666-675 10 p.

Research output: Contribution to journalArticle

Metformin
Mammography
Breast Neoplasms
Incidence
Medicare
184 Citations

Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

EXSCEL Study Group, Sep 28 2017, In : New England Journal of Medicine. 377, 13, p. 1228-1239 12 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Placebos
Cardiovascular Diseases
Cause of Death
Hospitalization
45 Citations

Effects of sotagliflozin added to insulin in patients with type 1 diabetes

Garg, S. K., Henry, R. R., Banks, P., Buse, J. B., Davies, M. J., Fulcher, G. R., Pozzilli, P., Gesty-Palmer, D., Lapuerta, P., Simó, R., Danne, T., McGuire, D. K., Kushner, J. A., Peters, A. & Strumph, P., Dec 14 2017, In : New England Journal of Medicine. 377, 24, p. 2337-2348 12 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Insulin
Placebos
Diabetic Ketoacidosis
Glycosylated Hemoglobin A
107 Citations

Efficacy and safety of degludec versus Glargine in Type 2 Diabetes

DEVOTE Study Group, Aug 24 2017, In : New England Journal of Medicine. 377, 8, p. 723-732 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Safety
Hypoglycemia
Glycosylated Hemoglobin A
Insulin
21 Citations

Glucose self-monitoring in non-insulin-treated patients with type 2 diabetes in primary care settings: A randomized trial

Young, L. A., Buse, J. B., Weaver, M. A., Vu, M. B., Mitchell, C. M., Blakeney, T., Grimm, K., Rees, J., Niblock, F. & Donahue, K. E., Jul 1 2017, In : JAMA internal medicine. 177, 7, p. 920-929 10 p.

Research output: Contribution to journalArticle

Blood Glucose Self-Monitoring
Type 2 Diabetes Mellitus
Primary Health Care
Glucose
Hemoglobins