Objective Physical Activity and Cardiovascular Health in Women Aged 80 and Older

Project: Research project


The purpose of this four year project is to more precisely define the health benefits of regular physical activity in women aged 80 and older by using accelerometers to characterize the amounts and patterns of physical activity. The specific aims are:
1) To determine the associations between objective measurements of physical activity using an accelerometer, and risk of incident CVD;
2) To compare the magnitude of associations between self-reported and accelerometer measures of physical activity with incident CVD;
3) To conduct a calibration study designed to determine accelerometry thresholds for women ages 80 and older that distinguish sedentary from light activity and light activity from moderate to vigorous activity.
3.1) Using the calibrated cutpoints, associations between intensity of physical activity and incident CVD will be examined.
4) To determine how level of physical activity influences risk of fall-related injuries and overall risk for any injury.
To accomplish these aims, 8,000 home visits will be conducted nationwide among participants from the Women’s Health Initiative (WHI). Participants will wear an accelerometer for 7 days, complete the CHAMPS and WHI physical activity questionnaires and will be followed for at least 3.5 years to ascertain study outcomes. For the calibration study, multiple WHI clinics will recruit women to obtain measures of physical fitness. This study would make a major contribution as to how patterns of aerobic activity relate to risk of adverse health outcomes among older women.
Effective start/end date5/1/144/30/16


  • Fred Hutchinson Cancer Research Center


Women's Health
House Calls
Physical Fitness
Wounds and Injuries
Insurance Benefits
Outcome Assessment (Health Care)