The overall goal of the proposed project is to define the contribution of joint hypermobility to lower body osteoarthritis (OA). Results of this study will inform clinical practice and determine groups at high risk for OA who require targeted prevention or intervention approaches. The rationale for the proposed research is that: 1) joint hypermobility changes joint mechanics, 2) joint hypermobility is an expected independent risk factor for OA, and 3) joint hypermobility increases the risk of injury, a major risk factor for OA. The central hypothesis is that joint hypermobility is associated with lower body OA (lumbar spine, hips, knees, ankles, and feet) and that joint hypermobility magnifies the effects of other OA risk factors (i.e., joint injury).
|Effective start/end date||5/1/15 → 4/30/19|
- NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMSD)
Wounds and Injuries