Comparative Effectiveness of Endocrine Therapy and Radiation Therapy Regimens for Elderly Breast Cancer Patients with Suboptimal Adherence.

Project: Research project

Description

Taking endocrine therapy (ET) for 5 years after breast cancer diagnosis has shown to greatly reduce future recurrence and extend survival in women with hormone-sensitive tumors. In spite of these benefits, as many as 50% of women prescribed ET fail to comply with the medication. In such cases, the survival benefits of ET become demonstrably diminished, if not all together negated. Unfortunately, a strong risk factor believed to contribute to treatment non-compliance is advanced age. Low compliance with adjuvant ET within the geriatric population is particularly troubling, given that the negative clinical consequences associated with non-compliance may necessitate further treatment which can be particularly complex in the elderly population.
StatusFinished
Effective start/end date7/1/156/30/17

Funding

  • American Society for Therapeutic Radiology and Oncology (ASTRO)

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Radiotherapy
Breast Neoplasms
Therapeutics
Survival
Geriatrics
Population
Hormones
Recurrence
Neoplasms