Research Output 1986 2017

2017

Adeno-Associated Virus–Mediated Mini-Agrin Delivery Is Unable to Rescue Disease Phenotype in a Mouse Model of Limb Girdle Muscular Dystrophy Type 2I

Vannoy, C. H., Zhou, H., Qiao, C., Xiao, X., Bang, A. G. & Lu, Q. L. Feb 1 2017 In : American Journal of Pathology. 187, 2, p. 431-440 10 p.

Research output: Contribution to journalArticle

Agrin
Dependovirus
Phenotype
Dystroglycans
Laminin
2016
3 Citations

Effect of Resveratrol-Based Nutritional Supplement on Choroidal Thickness: A Pilot Study

Wang, S., Moonasar, N., Xiao, X., Yin, T., Weinreb, R. N. & Sun, X. Feb 11 2016 (Accepted/In press) In : Current Eye Research. p. 1-7 7 p.

Research output: Contribution to journalArticle

Placebos
Optical Coherence Tomography
Control Groups
Nose
Vasodilation
2015
24 Citations

Adeno-associated virus type 2 and hepatocellular carcinoma?

Berns, K. I., Byrne, B. J., Flotte, T. R., Gao, G., Hauswirth, W. W., Herzog, R. W., Muzyczka, N., Vandendriessche, T., Xiao, X., Zolotukhin, S. & Srivastava, A. Dec 1 2015 In : Human Gene Therapy. 26, 12, p. 779-781 3 p.

Research output: Contribution to journalArticle

13 Citations

Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo

Ling, C., Wang, Y., Lu, Y., Wang, L., Jayandharan, G. R., Aslanidi, G. V., Li, B., Cheng, B., Ma, W., Lentz, T., Ling, C., Xiao, X., Jude Samulski, R., Muzyczka, N. & Srivastava, A. Jan 1 2015 In : Journal of Virology. 89, 2, p. 952-961 10 p.

Research output: Contribution to journalArticle

Dependovirus
human cell lines
Terminal Repeat Sequences
Transgenes
hepatocytes
2 Citations

GRAF1 deficiency blunts sarcolemmal injury repair and exacerbates cardiac and skeletal muscle pathology in dystrophin-deficient mice

Lenhart, K. C., O'Neill, T. J., Cheng, Z., Dee, R., Demonbreun, A. R., Li, J., Xiao, X., McNally, E. M., Mack, C. P. & Taylor, J. M. Aug 21 2015 In : Skeletal Muscle. 5, 1, 27

Research output: Contribution to journalArticle

Focal Adhesion Kinase 1
Dystrophin
Nonpenetrating Wounds
GTP Phosphohydrolases
Myocardium
9 Citations

Loss-of-function PTPRD mutations lead to increased STAT3 activation and sensitivity to STAT3 inhibition in head and neck cancer

Peyser, N. D., Du, Y., Li, H., Lui, V., Xiao, X., Chan, T. A. & Grandis, J. R. Aug 12 2015 In : PLoS ONE. 10, 8, e0135750

Research output: Contribution to journalArticle

Class 2 Receptor-Like Protein Tyrosine Phosphatases
protein-tyrosine-phosphatase
Head and Neck Neoplasms
Chemical activation
squamous cell carcinoma
4 Citations

Overcoming insulin insufficiency by forced follistatin expression in β-cells of db/db mice

Zhao, C., Qiao, C., Tang, R. H., Jiang, J., Li, J., Martin, C. B., Bulaklak, K., Li, J., Wang, D. W. & Xiao, X. Jan 1 2015 In : Molecular Therapy. 23, 5, p. 866-874 9 p.

Research output: Contribution to journalArticle

Follistatin
Insulin
Pancreas
Cell Proliferation
Myostatin
23 Citations

The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer

Xu, W., Neill, T., Yang, Y., Hu, Z., Cleveland, E., Wu, Y., Hutten, R., Xiao, X., Stock, S. R., Shevrin, D., Kaul, K., Brendler, C., Iozzo, R. V. & Seth, P. Mar 9 2015 In : Gene Therapy. 22, 3, p. 247-256 10 p.

Research output: Contribution to journalArticle

Decorin
Adenoviridae
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
2014
14 Citations

Adeno-associated virus-mediated overexpression of LARGE rescues α-dystroglycan function in dystrophic mice with mutations in the fukutin-related protein

Vannoy, C. H., Xu, L., Keramaris, E., Lu, P., Xiao, X. & Lu, Q. L. Jun 1 2014 In : Human Gene Therapy Methods. 25, 3, p. 187-196 10 p.

Research output: Contribution to journalArticle

Dystroglycans
Dependovirus
Glycosylation
Mutation
Genes
11 Citations

An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models

Gérard, C., Xiao, X., Filali, M., Coulombe, Z., Arsenault, M., Couet, J., Li, J., Drolet, M. C., Chapdelaine, P., Chikh, A. & Tremblay, J. P. Jan 8 2014 In : Molecular Therapy - Methods and Clinical Development. 1, 1 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
MM Form Creatine Kinase
Dependovirus
Phosphopyruvate Hydratase
Genes
37 Citations

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer

Lui, V. W. Y. , Peyser, N. D. , Ng, P. K. S. , Hritz, J. , Zeng, Y. , Lu, Y. , Li, H. , Wang, L. , Gilbert, B. R. , General, I. J. , Bahar, I. , Ju, Z. , Wang, Z. , Pendleton, K. P. , Xiao, X. , Du, Y. , Vries, J. K. , Hammerman, P. S. , Garraway, L. A. , Mills, G. B. & 2 others Johnson, D. E. & Grandis, J. R. Jan 21 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1114-1119 6 p.

Research output: Contribution to journalArticle

Protein Tyrosine Phosphatases
Head and Neck Neoplasms
Mutation
Receptor-Like Protein Tyrosine Phosphatases
Exome
9 Citations

GRAF1 promotes ferlin-dependent myoblast fusion

Lenhart, K. C., Becherer, A. L., Li, J., Xiao, X., McNally, E. M., Mack, C. P. & Taylor, J. M. Jan 1 2014 In : Developmental Biology. 393, 2, p. 298-311 14 p.

Research output: Contribution to journalArticle

Myoblasts
Muscles
Actins
Membranes
Skeletal Muscle Fibers
12 Citations

Intratumoral decorin gene delivery by AAV vector inhibits brain glioblastomas and prolongs survival of animals by inducing cell differentiation

Ma, H. I., Hueng, D. Y., Shui, H. A., Han, J. M., Wang, C. H., Lai, Y. H., Cheng, S. Y., Xiao, X., Chen, M. T. & Yang, Y. P. Mar 12 2014 In : International Journal of Molecular Sciences. 15, 3, p. 4393-4414 22 p.

Research output: Contribution to journalArticle

Decorin
Glioblastoma
genes
brain
animals
4 Citations

K137R Mutation on adeno-associated viral capsids had minimal effect on enhancing gene delivery in vivo

Qiao, C., Li, C., Zhao, C., Li, J., Bian, T., Grieger, J., Li, J., Samulski, R. J. & Xiao, X. Feb 1 2014 In : Human gene therapy methods. 25, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

Capsid
Mutation
Lac Operon
Luciferases
Transgenes
11 Citations

Muscle and heart function restoration in a limb girdle muscular dystrophy 2I (LGMD2I) mouse model by systemic FKRP gene delivery

Qiao, C., Wang, C. H., Zhao, C., Lu, P., Awano, H., Xiao, B., Li, J., Yuan, Z., Dai, Y., Martin, C. B., Li, J., Lu, Q. & Xiao, X. Jul 22 2014 In : Molecular Therapy. 22, 11, p. 1890-1899 10 p.

Research output: Contribution to journalArticle

Limb-Girdle Muscular Dystrophies
Myocardium
Walker-Warburg Syndrome
Dystroglycans
Genetic Therapy
2013
25 Citations

Adeno-associated Virus 9 mediated FKRP gene therapy restores functional glycosylation of α-dystroglycan and improves muscle functions

Xu, L., Lu, P. J., Wang, C. H., Keramaris, E., Qiao, C., Xiao, B., Blake, D. J., Xiao, X. & Lu, Q. L. Oct 1 2013 In : Molecular Therapy. 21, 10, p. 1832-1840 9 p.

Research output: Contribution to journalArticle

Walker-Warburg Syndrome
Dystroglycans
Dependovirus
Muscular Dystrophies
Glycosylation
7 Citations

Creation of a cardiotropic adeno-associated virus: The story of viral directed evolution

Yang, L. & Xiao, X. 2013 In : Virology Journal. 10, 50

Research output: Contribution to journalReview article

Dependovirus
DNA Shuffling
Genes
Protein Engineering
Genetic Therapy
18 Citations

Mouse models of fukutin-related protein mutations show a wide range of disease phenotypes

Blaeser, A., Keramaris, E., Chan, Y. M., Sparks, S., Cowley, D., Xiao, X. & Lu, Q. L. Aug 2013 In : Human Genetics. 132, 8, p. 923-934 12 p.

Research output: Contribution to journalArticle

Phenotype
Mutation
Walker-Warburg Syndrome
Glycosylation
Muscular Dystrophies
19 Citations

Pentamethylquercetin protects against diabetes-related cognitive deficits in diabetic goto-kakizaki rats

Li, X. H., Xin, X., Wang, Y., Wu, J. Z., Jin, Z. D., Ma, L. N., Nie, C. J., Xiao, X., Hu, Y. & Jin, M. W. Apr 24 2013 In : Journal of Alzheimer's Disease. 34, 3, p. 755-767 13 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Dendritic Spines
Insulin Resistance
Neurons
Glucose
4 Citations

Persistence, localization, and external control of transgene expression after single injection of adeno-associated virus into injured joints

Lee, H. H., O'Malley, M. J., Friel, N. A., Payne, K. A., Qiao, C., Xiao, X. & Chu, C. R. Apr 1 2013 In : Human Gene Therapy. 24, 4, p. 457-466 10 p.

Research output: Contribution to journalArticle

Dependovirus
Transgenes
Joints
Injections
Luciferases
9 Citations

Translating the genomics revolution: The need for an international gene therapy consortium for monogenic diseases

Tremblay, J. P. , Xiao, X. , Aartsma-Rus, A. , Barbas, C. , Blau, H. M. , Bogdanove, A. J. , Boycott, K. , Braun, S. , Breakefield, X. O. , Bueren, J. A. , Buschmann, M. , Byrne, B. J. , Calos, M. , Cathomen, T. , Chamberlain, J. , Chuah, M. , Cornetta, K. , Davies, K. E. , Dickson, J. G. , Duchateau, P. & 30 others Flotte, T. R., Gaudet, D., Gersbach, C. A., Gilbert, R., Glorioso, J., Herzog, R. W., High, K. A., Huang, W., Huard, J., Joung, J. K., Liu, D., Liu, D., Lochmüller, H., Lustig, L., Martens, J., Massie, B., Mavilio, F., Mendell, J. R., Nathwani, A., Ponder, K., Porteus, M., Puymirat, J., Samulski, J., Takeda, S. I., Thrasher, A., Vandendriessche, T., Wei, Y., Wilson, J. M., Wilton, S. D. & Wolfe, J. H. Feb 1 2013 In : Molecular Therapy. 21, 2, p. 266-268 3 p.

Research output: Contribution to journalLetter

International Cooperation
Genomics
Genetic Therapy
Biomedical Research
2012
77 Citations

Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

Kornegay, J. N., Bogan, J. R., Bogan, D. J., Childers, M. K., Li, J., Nghiem, P., Detwiler, D. A., Larsen, C. A., Grange, R. W., Bhavaraju-Sanka, R. K., Tou, S., Keene, B. P., Howard, J. F., Wang, J., Fan, Z., Schatzberg, S. J., Styner, M. A., Flanigan, K. M., Xiao, X. & Hoffman, E. P. Feb 2012 In : Mammalian Genome. 23, 1-2, p. 85-108 24 p.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Muscular Dystrophies
Therapeutic Uses
Canidae
Dystrophin
37 Citations

Enhancing muscle membrane repair by gene delivery of MG53 ameliorates muscular dystrophy and heart failure inδ-sarcoglycan-deficient hamsters

He, B., Tang, R. H., Weisleder, N., Xiao, B., Yuan, Z., Cai, C., Zhu, H., Lin, P., Qiao, C., Li, J., Mayer, C., Li, J., Ma, J. & Xiao, X. Apr 1 2012 In : Molecular Therapy. 20, 4, p. 727-735 9 p.

Research output: Contribution to journalArticle

Sarcoglycans
Muscular Dystrophies
Cricetinae
Heart Failure
Muscles
162 Citations

Phase 1 gene therapy for duchenne muscular dystrophy using a translational optimized AAV vector

Bowles, D. E., McPhee, S. W. J., Li, C., Gray, S. J., Samulski, J. J., Camp, A. S., Li, J., Wang, B., Monahan, P. E., Rabinowitz, J. E., Grieger, J. C., Govindasamy, L., Agbandje-Mckenna, M., Xiao, X. & Samulski, R. J. Feb 1 2012 In : Molecular Therapy. 20, 2, p. 443-455 13 p.

Research output: Contribution to journalArticle

Dependovirus
Duchenne Muscular Dystrophy
Capsid
Genetic Therapy
Arm
14 Citations

Single tyrosine mutation in AAV8 and AAV9 capsids is insufficient to enhance gene delivery to skeletal muscle and heart

Qiao, C., Yuan, Z., Li, J., Tang, R., Li, J. & Xiao, X. Feb 1 2012 In : Human Gene Therapy Methods. 23, 1, p. 29-37 9 p.

Research output: Contribution to journalArticle

Capsid
Tyrosine
Skeletal Muscle
Mutation
Genes
2011
11 Citations
Dependovirus
Cell Line
Product Packaging
Transfection
Plasmids
111 Citations

Current status of pharmaceutical and genetic therapeutic approaches to treat DMD

Pichavant, C., Aartsma-Rus, A., Clemens, P. R., Davies, K. E., Dickson, G., Takeda, S. I., Wilton, S. D., Wolff, J. A., Wooddell, C. I., Xiao, X. & Tremblay, J. P. May 1 2011 In : Molecular Therapy. 19, 5, p. 830-840 11 p.

Research output: Contribution to journalArticle

Dystrophin
Duchenne Muscular Dystrophy
Genetic Therapy
Pharmaceutical Preparations
Muscles
11 Citations

Delta-Sarcoglycan gene therapy halts progression of cardiac dysfunction, improves respiratory failure, and prolongs life in myopathic hamsters

Hoshijima, M., Hayashi, T., Jeon, Y. E., Fu, Z., Gu, Y., Dalton, N. D., Ellisman, M. H., Xiao, X., Powell, F. L. & Ross, J. Jan 1 2011 In : Circulation: Heart Failure. 4, 1, p. 89-97 9 p.

Research output: Contribution to journalArticle

Sarcoglycans
Cricetinae
Respiratory Insufficiency
Genetic Therapy
Myocardium
14 Citations

Directed evolution of adeno-associated virus (AAV) as vector for muscle gene therapy.

Yang, L., Li, J. & Xiao, X. Jul 12 2011 In : Methods in molecular biology (Clifton, N.J.). 709, p. 127-139 13 p.

Research output: Contribution to journalArticle

Dependovirus
Capsid
Genetic Therapy
Muscles
Genes
63 Citations

DOT1L regulates dystrophin expression and is critical for cardiac function

Nguyen, A. T., Xiao, B., Neppl, R. L., Kallin, E. M., Li, J., Chen, T., Wang, D. Z., Xiao, X. & Zhang, Y. Feb 1 2011 In : Genes and Development. 25, 3, p. 263-274 12 p.

Research output: Contribution to journalArticle

Dystrophin
Cardiac Myocytes
Dilated Cardiomyopathy
Methylation
Histones
6 Citations

Gene therapy in skeletal muscle mediated by adeno-associated virus vectors

Qiao, C., Koo, T., Li, J., Xiao, X. & Dickson, J. G. Dec 19 2011 Adeno-Associated Virus: Methods and Protocols. Vol. 807, p. 119-140 22 p. (Methods in Molecular Biology; vol. 807)

Research output: Chapter in Book/Report/Conference proceedingChapter

Dependovirus
Genetic Therapy
Skeletal Muscle
Muscles
Transgenes
64 Citations

Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver

Qiao, C., Yuan, Z., Li, J., He, B., Zheng, H., Mayer, C., Li, J. & Xiao, X. Apr 1 2011 In : Gene Therapy. 18, 4, p. 403-410 8 p.

Research output: Contribution to journalArticle

Dependovirus
MicroRNAs
Transgenes
Liver
Luciferases
37 Citations

One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice

Wu, B., Xiao, B., Cloer, C., Shaban, M., Sali, A., Lu, P., Li, J., Nagaraju, K., Xiao, X. & Lu, Q. L. Mar 1 2011 In : Molecular Therapy. 19, 3, p. 576-583 8 p.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Morpholinos
Dystrophin
Myocardium
Skeletal Muscle
8 Citations

Phosphorylation of the anaphase-promoting complex/Cdc27 is involved in TGF-β signaling

Zhang, L., Fujita, T., Wu, G., Xiao, X. & Wan, Y. Mar 25 2011 In : Journal of Biological Chemistry. 286, 12, p. 10041-10050 10 p.

Research output: Contribution to journalArticle

Anaphase-Promoting Complex-Cyclosome
Phosphorylation
Transforming Growth Factor beta
Casein Kinase II
Chemical activation
8 Citations

Post-natal knockdown of fukutin-related protein expression in muscle by long-term RNA interference induces dystrophic pathology

Wang, C. H., Chan, Y. M., Tang, R. H., Xiao, B., Lu, P., Keramaris-Vrantsis, E., Zheng, H., Qiao, C., Jiang, J., Li, J., Ma, H. I., Lu, Q. & Xiao, X. 2011 In : American Journal of Pathology. 178, 1, p. 261-272 12 p.

Research output: Contribution to journalArticle

Limb-Girdle Muscular Dystrophies
RNA Interference
Small Interfering RNA
Pathology
Muscles
35 Citations

Release of bioactive adeno-associated virus from fibrin scaffolds: Effects of fibrin glue concentrations

Lee, H. H., Haleem, A. M., Yao, V., Li, J., Xiao, X. & Chu, C. R. Aug 1 2011 In : Tissue Engineering - Part A. 17, 15-16, p. 1969-1978 10 p.

Research output: Contribution to journalArticle

Dependovirus
Fibrin Tissue Adhesive
Glues
Fibrin
Viruses
20 Citations

Single intra-articular injection of adeno-associated virus results in stable and controllable in vivo transgene expression in normal rat knees

Payne, K. A., Lee, H. H., Haleem, A. M., Martins, C., Yuan, Z., Qiao, C., Xiao, X. & Chu, C. R. Aug 1 2011 In : Osteoarthritis and Cartilage. 19, 8, p. 1058-1065 8 p.

Research output: Contribution to journalArticle

Intra-Articular Injections
Dependovirus
Transgenes
Viruses
Tetracycline
2010
3 Citations

Adeno-associated viral vectors found free in media

Xiao, X. Oct 1 2010 In : Human Gene Therapy. 21, 10, p. 1221-1222 2 p.

Research output: Contribution to journalComment/debate

Virus Release
Specimen Handling
Gene Transfer Techniques
Heparan Sulfate Proteoglycans
Genetic Vectors
44 Citations

Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle

Qiao, C., Zhang, W., Yuan, Z., Shin, J. H., Li, J., Jayandharan, G. R., Zhong, L., Srivastava, A., Xiao, X. & Duan, D. Oct 1 2010 In : Human Gene Therapy. 21, 10, p. 1343-1348 6 p.

Research output: Contribution to journalArticle

Dependovirus
Capsid
Phenylalanine
Genetic Therapy
Tyrosine
13 Citations

Differential antitumor effect of interleukin-12 family cytokines on orthotopic hepatocellular carcinoma

Lo, C. H., Chang, C. M., Tang, S. W., Pan, W. Y., Fang, C. C., Chen, Y., Wu, P. Y., Chen, K. Y., Ma, H. I., Xiao, X. & Tao, M. H. May 2010 In : Journal of Gene Medicine. 12, 5, p. 423-434 12 p.

Research output: Contribution to journalArticle

Interleukin-12
Dependovirus
Hepatocellular Carcinoma
Interleukin-27
Interleukin-23
266 Citations

Dystrophin immunity in Duchenne's muscular dystrophy

Mendell, J. R., Campbell, K., Rodino-Klapac, L., Sahenk, Z., Shilling, C., Lewis, S., Bowles, D., Gray, S., Li, C., Galloway, G., Malik, V., Coley, B., Clark, K. R., Li, J., Xiao, X., Samulski, J., McPhee, S. W., Samulski, R. J. & Walker, C. M. Oct 7 2010 In : New England Journal of Medicine. 363, 15, p. 1429-1437 9 p.

Research output: Contribution to journalArticle

Dystrophin
Duchenne Muscular Dystrophy
Immunity
T-Lymphocytes
Transgenes
24 Citations

Efficient retrograde transport of adeno-associated virus type 8 to spinal cord and dorsal root ganglion after vector delivery in muscle

Zheng, H., Qiao, C., Wang, C. H., Li, J., Li, J., Yuan, Z., Zhang, C. & Xiao, X. Jan 1 2010 In : Human Gene Therapy. 21, 1, p. 87-97 11 p.

Research output: Contribution to journalArticle

Dependovirus
Spinal Nerve Roots
Spinal Ganglia
Spinal Cord
Muscles
21 Citations

Expression of dog microdystrophin in mouse and dog muscles by gene therapy

Pichavant, C., Chapdelaine, P., Cerri, D. G., Dominique, J. C., Quenneville, S. P., Skuk, D., Kornegay, J. N., Bizario, J. C., Xiao, X. & Tremblay, J. P. May 1 2010 In : Molecular Therapy. 18, 5, p. 1002-1009 8 p.

Research output: Contribution to journalArticle

Genetic Therapy
Duchenne Muscular Dystrophy
Dogs
Muscles
Dystrophin
21 Citations

Improvement of the mdx mouse dystrophic phenotype by systemic in utero AAV8 delivery of a minidystrophin gene

Koppanati, B. M., Li, J., Reay, D. P., Wang, B., Daood, M., Zheng, H., Xiao, X., Watchko, J. F. & Clemens, P. R. Nov 1 2010 In : Gene Therapy. 17, 11, p. 1355-1362 8 p.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Dystrophin
Duchenne Muscular Dystrophy
Skeletal Muscle
Phenotype
17 Citations

Long-term protection against human papillomavirus E7-positive tumor by a single vaccination of adeno-associated virus vectors encoding a fusion protein of inactivated E7 of human papillomavirus 16/18 and heat shock protein 70

Zhou, L., Zhu, T., Ye, X., Yang, L., Wang, B., Liang, X., Lu, L., Tsao, Y. P., Chen, S. L., Li, J. & Xiao, X. Jan 1 2010 In : Human Gene Therapy. 21, 1, p. 109-119 11 p.

Research output: Contribution to journalArticle

Human papillomavirus 18
Dependovirus
HSP70 Heat-Shock Proteins
Human papillomavirus 16
Vaccination
268 Citations

microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7

Chen, J. F., Tao, Y., Li, J., Deng, Z., Yan, Z., Xiao, X. & Wang, D. Z. Sep 6 2010 In : Journal of Cell Biology. 190, 5, p. 867-879 13 p.

Research output: Contribution to journalArticle

Skeletal Muscle Satellite Cells
MicroRNAs
Cell Differentiation
Paired Box Transcription Factors
Cell Proliferation

Muscular dystrophy gene therapy in small animal models

Qiao, C. & Xiao, X. 2010 Muscle Gene Therapy. Springer New York, p. 55-68 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gene therapy
Muscular Dystrophies
Genetic Therapy
Dystrophin
Animals
35 Citations

Overexpression of Cytochrome P450 Epoxygenases Prevents Development of Hypertension in Spontaneously Hypertensive Rats by Enhancing Atrial Natriuretic Peptide

Xiao, B., Li, X., Yan, J., Yu, X., Yang, G., Xiao, X., Voltz, J. W., Zeldin, D. C. & Wang, D. W. Sep 1 2010 In : Journal of Pharmacology and Experimental Therapeutics. 334, 3, p. 784-794 11 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Inbred SHR Rats
Cytochrome P-450 Enzyme System
Hypertension
Epidermal Growth Factor Receptor
78 Citations

Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs

Kornegay, J. N., Li, J., Bogan, J. R., Bogan, D. J., Chen, C., Zheng, H., Wang, B., Qiao, C., Howard, J. F. & Xiao, X. Aug 1 2010 In : Molecular Therapy. 18, 8, p. 1501-1508 8 p.

Research output: Contribution to journalArticle

Dystrophin
Intravenous Injections
Dogs
Muscles
Extremities
2009
36 Citations

A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery

Yu, C. Y., Yuan, Z., Cao, Z., Wang, B., Qiao, C., Li, J. & Xiao, X. Jun 5 2009 In : Gene Therapy. 16, 8, p. 953-962 10 p.

Research output: Contribution to journalArticle

Tropism
Dependovirus
Muscles
Peptides
Heparin