• 2234 Citations
  • 22 h-Index
19952018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 16 Similar Profiles
Inflammasomes Medicine & Life Sciences
Major Histocompatibility Complex Medicine & Life Sciences
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Sputum Medicine & Life Sciences
Lung Medicine & Life Sciences
Interleukin-18 Medicine & Life Sciences
Allografts Medicine & Life Sciences
Leucine Medicine & Life Sciences

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Projects 2004 2015

Radiation Injuries
Burns
Immunosuppressive Agents
Radioactive Hazard Release
Wounds and Injuries
Radiation Injuries
Immunomodulation
Burns
Monocytes

Research Output 1995 2018

  • 2234 Citations
  • 22 h-Index
  • 41 Article
  • 2 Letter
  • 1 Chapter

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis

Truax, A. D., Chen, L., Tam, J. W., Cheng, N., Guo, H., Koblansky, A. A., Chou, W. C., Wilson, J. E., Brickey, W. J., Petrucelli, A., Liu, R., Cooper, D. E., Koenigsknecht, M. J., Young, V. B., Netea, M. G., Stienstra, R., Sartor, R. B., Montgomery, S. A., Coleman, R. A. & Ting, J. P., Sep 12 2018, In : Cell Host and Microbe. 24, 3, p. 364-378.e6

Research output: Contribution to journalArticle

Homeostasis
Obesity
High Fat Diet
Microbiota
Inflammation

Innate immune cell recovery is positively regulated by NLRP12 during emergency hematopoiesis

Linz, B. M. L., Neely, C. J., Kartchner, L. B., Mendoza, A. E., Khoury, A. L., Truax, A., Sempowski, G., Eitas, T., Brickey, J., Ting, J. P. Y., Cairns, B. A. & Maile, R., Mar 15 2017, In : Journal of Immunology. 198, 6, p. 2426-2433 8 p.

Research output: Contribution to journalArticle

Hematopoiesis
Emergencies
Hot Temperature
Wounds and Injuries
Radiation
25 Citations

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

Freeman, L., Guo, H., David, C. N., Brickey, W. J., Jha, S. & Ting, J. P. Y., May 1 2017, In : Journal of Experimental Medicine. 214, 5, p. 1351-1370 20 p.

Research output: Contribution to journalArticle

Inflammasomes
Microglia
Astrocytes
Lysophosphatidylcholines
Caspase 1
29 Citations

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth

Chen, L., Wilson, J. E., Koenigsknecht, M. J., Chou, W. C., Montgomery, S. A., Truax, A. D., Brickey, W. J., Packey, C. D., Maharshak, N., Matsushima, G. K., Plevy, S. E., Young, V. B., Sartor, R. B. & Ting, J. P., Apr 18 2017, In : Nature Immunology. 18, 5, p. 541-551 11 p.

Research output: Contribution to journalArticle

Microbiota
Dysbiosis
Colon
Inflammation
Growth
13 Citations

Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer

Taylor, N. A., Vick, S. C., Iglesia, M. D., Brickey, W. J., Midkiff, B. R., Mckinnon, K. P., Reisdorf, S., Anders, C. K., Carey, L. A., Parker, J., Perou, C. M., Vincent, B. G. & Serody, J. S., Sep 1 2017, In : Journal of Clinical Investigation. 127, 9, p. 3472-3483 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Tumor Microenvironment
Neoplasms
TNF-Related Apoptosis-Inducing Ligand Receptors
Tumor-Infiltrating Lymphocytes