Research Output 1995 2017

2017
2 Citations

Age at diagnosis, obesity, smoking, and molecular subtypes in muscle-invasive bladder cancer

Sun, X., Hoadley, K. A., Kim, W. Y., Furberg, H., Olshan, A. F. & Troester, M. A. Jun 1 2017 In : Cancer Causes and Control. 28, 6, p. 539-544 6 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Obesity
Smoking
Muscles
Atlases
2016
5 Citations

Intrinsic genomic differences between african American and white patients with clear cell renal cell carcinoma

Krishnan, B., Rose, T. L., Kardos, J., Milowsky, M. I. & Kim, W. Y. May 1 2016 In : JAMA Oncology. 2, 5, p. 664-667 4 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
African Americans
Mutation Rate
Neoplasms
RNA
3 Citations

Racial disparities in survival among patients with advanced renal cell carcinoma in the targeted therapy era

Rose, T. L., Deal, A. M., Krishnan, B., Nielsen, M. E., Smith, A. B., Kim, W. Y. & Milowsky, M. I. Jan 1 2016 (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
African Americans
Survival
Therapeutics
Confidence Intervals
2015
70 Citations

Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

Chandler, R. L., Damrauer, J. S., Raab, J. R., Schisler, J. C., Wilkerson, M. D., Didion, J. P., Starmer, J., Serber, D., Yee, D., Xiong, J., Darr, D. B., De Villena, F. P. M., Kim, W. Y. & Magnuson, T. Jan 1 2015 In : Nature Communications. 6, 6118

Research output: Contribution to journalArticle

mutations
Tumors
Carcinogenesis
cancer
Cytokines
8 Citations

Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

Rager, J. E., Tilley, S. K., Tulenko, S. E., Smeester, L., Ray, P. D., Yosim, A., Currier, J. M., Ishida, M. C., González-Horta, M. D. C., Sánchez-Ramírez, B., Ballinas-Casarrubias, L., Gutiérrez-Torres, D. S., Drobná, Z., Del Razo, L. M., García-Vargas, G. G., Kim, W. Y., Zhou, Y. H., Wright, F. A., Stýblo, M. & Fry, R. C. Jun 15 2015 In : Chemical Research in Toxicology. 28, 6, p. 1144-1155 12 p.

Research output: Contribution to journalArticle

Arsenic
DNA Methylation
Urinary Bladder Neoplasms
Genes
Methylation
24 Citations

Nanoparticle modulation of the tumor microenvironment enhances therapeutic efficacy of cisplatin

Miao, L., Wang, Y., Lin, C. M., Xiong, Y., Chen, N., Zhang, L., Kim, W. Y. & Huang, L. Nov 10 2015 In : Journal of Controlled Release. 217, p. 27-41 15 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Nanoparticles
Cisplatin
Therapeutics
Phenotype
3 Citations
Cystectomy
Urinary Bladder Neoplasms
Drug Therapy
Muscles
Patient Transfer
12 Citations

Targeting tumor hypoxia with hypoxia-activated prodrugs

Yeh, J. J. & Kim, W. Y. May 1 2015 In : Journal of Clinical Oncology. 33, 13, p. 1505-1508 4 p.

Research output: Contribution to journalArticle

Antineoplastic Combined Chemotherapy Protocols
Prodrugs
Pancreatic Neoplasms
Hypoxia
Tumor Hypoxia
2014
904 Citations

Comprehensive molecular characterization of urothelial bladder carcinoma

Weinstein, J. N. , Akbani, R. , Broom, B. M. , Wang, W. , Verhaak, R. G. W. , McConkey, D. , Lerner, S. , Morgan, M. , Creighton, C. J. , Smith, C. , Cherniack, A. D. , Kim, J. , Pedamallu, C. S. , Noble, M. S. , Al-Ahmadie, H. A. , Reuter, V. E. , Rosenberg, J. E. , F.Bajorin, D. , Bochner, B. H. , Solit, D. B. & 30 others Koppie, T., Robinson, B., Gordenin, D. A., Fargo, D., Klimczak, L. J., Roberts, S. A., Au, J., Laird, P. W., Hinoue, T., Schultz, N., Ramirez, R., Hansel, D., Hoadley, K. A., Kim, W. Y., Damrauer, J. S., Baylin, S. B., Mungall, A. J., Robertson, A. G., Chu, A., Kwiatkowski, D. J., Sougnez, C., Cibulskis, K., Parker, J. S., Hayes, D. N., Jones, C. D., Mieczkowski, P. A., Auman, J. T., Perou, C. M., Rathmell, W. K. & Thorne, L. Jan 1 2014 In : Nature. 507, 7492, p. 315-322 8 p.

Research output: Contribution to journalArticle

Urinary Bladder
Carcinoma
Chromatin
RNA Sequence Analysis
Neoplasms
27 Citations

Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

Zhou, B., Damrauer, J. S., Bailey, S. T., Hadzic, T., Jeong, Y., Clark, K., Fan, C., Murphy, L., Lee, C. Y., Troester, M. A., Miller, C. R., Jin, J., Darr, D., Perou, C. M., Levine, R. L., Diehn, M. & Kim, W. Y. Feb 3 2014 In : Journal of Clinical Investigation. 124, 2, p. 553-563 11 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Erythropoietin
Carcinogenesis
Breast
Breast Neoplasms
4 Citations

Genetic evidence of a precisely tuned dysregulation in the hypoxia signaling pathway during oncogenesis

Couvé, S. , Ladroue, C. , Laine, E. , Mahtouk, K. , Guégan, J. , Gad, S. , Le Jeune, H. , Le Gentil, M. , Nuel, G. , Kim, W. Y. , Lecomte, B. , Pagès, J. C. , Collin, C. , Lasne, F. , Benusiglio, P. R. , Bressac-De Paillerets, B. , Feunteun, J. , Lazar, V. , Gimenez-Roqueplo, A. P. , Mazure, N. M. & 7 others Dessen, P., Tchertanov, L., Mole, D. R., Kaelin, W., Ratcliffe, P., Richard, S. & Gardie, B. Nov 15 2014 In : Cancer Research. 74, 22, p. 6554-6564 11 p.

Research output: Contribution to journalArticle

Carcinogenesis
von Hippel-Lindau Disease
Mutation
Tumor Suppressor Genes
Hemangioblastoma
206 Citations

Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology

Damrauer, J. S., Hoadley, K. A., Chism, D. D., Fan, C., Tiganelli, C. J., Wobker, S. E., Yeh, J. J., Milowsky, M. I., Iyer, G., Parker, J. S. & Kim, W. Y. Feb 25 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 8, p. 3110-3115 6 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Breast Neoplasms
Gene Expression
Microarray Analysis
Standard of Care
12 Citations

mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma

Bailey, S. T., Zhou, B., Damrauer, J. S., Krishnan, B., Wilson, H. L., Smith, A. M., Li, M., Yeh, J. J. & Kim, W. Y. Jan 1 2014 In : PLoS ONE. 9, 9, e104413

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
kidney cells
Renal Cell Carcinoma
carcinoma
Chemical activation
3 Citations
Databases
Research
Medical Oncology
Research Ethics Committees
Radiation Oncology
43 Citations

Synergistic anti-tumor effects of combined gemcitabine and cisplatin nanoparticles in a stroma-rich bladder carcinoma model

Zhang, J., Miao, L., Guo, S., Zhang, Y., Zhang, L., Satterlee, A., Kim, W. Y. & Huang, L. May 28 2014 In : Journal of Controlled Release. 182, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

gemcitabine
Nanoparticles
Cisplatin
Urinary Bladder
Carcinoma
2 Citations
Urinary Bladder Neoplasms
Geriatrics
Cisplatin
Therapeutics
Standard of Care
33 Citations

Trends in stage-specific incidence rates for urothelial carcinoma of the bladder in the United States: 1988 to 2006

Nielsen, M. E., Smith, A. B., Meyer, A. M., Kuo, T. M., Tyree, S., Kim, W. Y., Milowsky, M. I., Pruthi, R. S. & Millikan, R. C. Jan 1 2014 In : Cancer. 120, 1, p. 86-95 10 p.

Research output: Contribution to journalArticle

Urinary Bladder
Carcinoma
Urinary Bladder Neoplasms
Incidence
Population
2013
32 Citations

A phase II study of lapatinib, a dual EGFR and HER-2 tyrosine kinase inhibitor, in patients with castration-resistant prostate cancer

Whang, Y. E., Armstrong, A. J., Rathmell, W. K., Godley, P. A., Kim, W. Y., Pruthi, R. S., Wallen, E. M., Crane, J. M., Moore, D. T., Grigson, G., Morris, K., Watkins, C. P. & George, D. J. Jan 1 2013 In : Urologic Oncology: Seminars and Original Investigations. 31, 1, p. 82-86 5 p.

Research output: Contribution to journalArticle

TYK2 Kinase
Castration
Epidermal Growth Factor Receptor
Prostatic Neoplasms
Therapeutics
59 Citations

Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC

Zhang, Y., Schwerbrock, N. M. J., Rogers, A. B., Kim, W. Y. & Huang, L. Aug 1 2013 In : Molecular Therapy. 21, 8, p. 1559-1569 11 p.

Research output: Contribution to journalArticle

gemcitabine
Non-Small Cell Lung Carcinoma
Nanoparticles
Vascular Endothelial Growth Factor A
Small Interfering RNA
71 Citations

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

Hanna, S. C., Krishnan, B., Bailey, S. T., Moschos, S. J., Kuan, P. F., Shimamura, T., Osborne, L. D., Siegel, M. B., Duncan, L. M., O'Brien, E. T., Superfine, R., Miller, C. R., Simon, M. C., Wong, K. K. & Kim, W. Y. May 1 2013 In : Journal of Clinical Investigation. 123, 5, p. 2078-2093 16 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Neoplasms
Matrix Metalloproteinase 14
Focal Adhesion Protein-Tyrosine Kinases
48 Citations

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1 -mutant lung cancer

Liu, Y. , Marks, K. , Cowley, G. S. , Carretero, J. , Liu, Q. , Niel, T. J. F. , Xu, C. , Cohoon, T. J. , Gao, P. , Zhang, Y. , Chen, Z. , Altabef, A. B. , Tchaicha, J. H. , Wang, X. , Choe, S. , Driggers, E. M. , Zhang, J. , Bailey, S. T. , Sharpless, N. E. , Neil Hayes, D. & 20 others Patel, N. M., Janne, P. A., Bardeesy, N., Engelman, J. A., Manning, B. D., Shaw, R. J., Asara, J. M., Scully, R., Kimmelman, A., Byers, L. A., Gibbons, D. L., Wistuba, I. I., Heymach, J. V., Kwiatkowski, D. J., Kim, W. Y., Kung, A. L., Gray, N. S., Root, D. E., Cantley, L. C. & Wong, K. K. Aug 1 2013 In : Cancer Discovery. 3, 8, p. 870-879 10 p.

Research output: Contribution to journalArticle

Thymidine Monophosphate
Lung Neoplasms
Phosphotransferases
Cations
Nucleotides
3 Citations

Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier

Ding, M., Coward, R. J., Jeansson, M., Kim, W. & Quaggin, S. E. Jan 1 2013 In : American Journal of Physiology - Renal Physiology. 304, 1

Research output: Contribution to journalArticle

Podocytes
Knockout Mice
Glomerulonephritis
Kidney
Phenotype
3 Citations

Stearoyl co-a desaturase 1 as a ccRCC therapeutic target: Death by stress

Leung, J. Y. & Kim, W. Y. Jun 15 2013 In : Clinical Cancer Research. 19, 12, p. 3111-3113 3 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Therapeutics
49 Citations

Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy

Zhang, Y., Kim, W. Y. & Huang, L. Apr 2013 In : Biomaterials. 34, 13, p. 3447-3458 12 p.

Research output: Contribution to journalArticle

Calcium phosphate
Pancreatic Neoplasms
Non-Small Cell Lung Carcinoma
Nanoparticles
Lipids
2012
102 Citations

Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer

Choueiri, T. K., Ross, R. W., Jacobus, S., Vaishampayan, U., Yu, E. Y., Quinn, D. I., Hahn, N. M., Hutson, T. E., Sonpavde, G., Morrissey, S. C., Buckle, G. C., Kim, W. Y., Petrylak, D. P., Ryan, C. W., Eisenberger, M. A., Mortazavi, A., Bubley, G. J., Taplin, M. E., Rosenberg, J. E. & Kantoff, P. W. Feb 10 2012 In : Journal of Clinical Oncology. 30, 5, p. 507-512 6 p.

Research output: Contribution to journalArticle

docetaxel
Platinum
Placebos
Disease-Free Survival
Neoplasms
5 Citations

Drug efficacy testing in mice

Kim, W. Y. & Sharpless, N. E. 2012 Therapeutic Kinase Inhibitors. Vol. 355, p. 19-38 20 p. (Current Topics in Microbiology and Immunology; vol. 355)

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmaceutical Preparations
Heterografts
Neoplasms
Phosphotransferases
Cell Line
295 Citations

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

Duncan, J. S. , Whittle, M. C. , Nakamura, K. , Abell, A. N. , Midland, A. A. , Zawistowski, J. S. , Johnson, N. L. , Granger, D. A. , Jordan, N. V. , Darr, D. B. , Usary, J. , Kuan, P. F. , Smalley, D. M. , Major, B. , He, X. , Hoadley, K. A. , Zhou, B. , Sharpless, N. E. , Perou, C. M. , Kim, W. Y. & 7 others Gomez, S. M., Chen, X., Jin, J., Frye, S. V., Earp, H. S., Graves, L. M. & Johnson, G. L. Apr 13 2012 In : Cell. 149, 2, p. 307-321 15 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Mitogen-Activated Protein Kinase Kinases
Receptor Protein-Tyrosine Kinases
Corrosion inhibitors
Drug Resistance
1 Citations

Erratum: Epidermal growth factor receptor and KRas mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors (Cancer DOI: 10.1002/cncr.26656)

Kim, W. Y., Prudkin, L., Feng, L., Kim, E. S., Hennessy, B., Lee, J. S., Lee, J. J., Glisson, B., Lippman, S. M., Wistuba, I. I., Hong, W. K. & Lee, H. Y. Dec 15 2012 In : Cancer. 118, 24, 1 p.

Research output: Contribution to journalComment/debate

Somatomedin Receptors
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Lung Neoplasms
Mutation
8 Citations
docetaxel
Androgens
Prostatic Neoplasms
Cohort Studies
Radiotherapy
87 Citations

State of the science: An update on renal cell carcinoma

Jonasch, E., Futreal, P. A., Davis, I. J., Bailey, S. T., Kim, W. Y., Brugarolas, J., Giaccia, A. J., Kurban, G., Pause, A., Frydman, J., Zurita, A. J., Rini, B. I., Sharma, P., Atkins, M. B., Walker, C. L. & Rathmell, W. K. Jul 2012 In : Molecular Cancer Research. 10, 7, p. 859-880 22 p.

Research output: Contribution to journalReview article

Renal Cell Carcinoma
Neoplasms
Mutation
Chromatin Assembly and Disassembly
Kidney Neoplasms
2011
33 Citations
Neoplasms
Therapeutics
Urinary Bladder Neoplasms
Prostatic Neoplasms
Urinary Bladder
10 Citations

A phase I trial of sorafenib combined with cisplatin/etoposide or carboplatin/pemetrexed in refractory solid tumor patients

Davies, J. M., Dhruva, N. S., Walko, C. M., Socinski, M. A., Bernard, S., Hayes, D. N., Kim, W. Y., Ivanova, A., Keller, K., Hilbun, L. R., Chiu, M., Dees, E. C. & Stinchcombe, T. E. Feb 1 2011 In : Lung Cancer. 71, 2, p. 151-155 5 p.

Research output: Contribution to journalArticle

Pemetrexed
Carboplatin
Etoposide
Cisplatin
Neoplasms
3 Citations

Carbon nanotube based respiratory gated micro-CT imaging of a murine model of lung tumors with optical imaging correlation

Burk, L. M., Lee, Y. Z., Heathcote, S., Wang, K. H., Kim, W. Y., Lu, J. & Zhou, O. May 16 2011 Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging. Vol. 7965, 79651L

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Carbon Nanotubes
Optical Imaging
Tumor Burden
lungs
Tumors
40 Citations

Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia

Russell, R. C., Sufan, R. I., Zhou, B., Heir, P., Bunda, S., Sybingco, S. S., Greer, S. N., Roche, O., Heathcote, S. A., Chow, V. W. K., Boba, L. M., Richmond, T. D., Hickey, M. M., Barber, D. L., Cheresh, D. A., Simon, M. C., Irwin, M. S., Kim, W. Y. & Ohh, M. Jul 1 2011 In : Nature Medicine. 17, 7, p. 845-853 9 p.

Research output: Contribution to journalArticle

Polycythemia
Ubiquitin-Protein Ligases
Cytokines
Genes
Erythropoietin
12 Citations
docetaxel
Estramustine
Prostatectomy
Prostatic Neoplasms
Radiotherapy
46 Citations

Two sides to every story: The HIF-dependent and HIF-independent functions of pVHL

Li, M. & Kim, W. Y. Feb 1 2011 In : Journal of Cellular and Molecular Medicine. 15, 2, p. 187-195 9 p.

Research output: Contribution to journalReview article

von Hippel-Lindau Disease
Carcinogenesis
Cilia
Extracellular Matrix
Hereditary Neoplastic Syndromes
2010
68 Citations
Cystectomy
Urinary Bladder Neoplasms
Muscles
Surgical Pathology
Neoadjuvant Therapy
35 Citations

HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer

Jackson, A. L., Zhou, B. & Kim, W. Y. Oct 1 2010 In : Expert Opinion on Therapeutic Targets. 14, 10, p. 1047-1057 11 p.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Tumors
Cells
Neoplasms
Vascular Endothelial Growth Factor Receptor
151 Citations

Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors

Carretero, J. , Shimamura, T. , Rikova, K. , Jackson, A. L. , Wilkerson, M. D. , Borgman, C. L. , Buttarazzi, M. S. , Sanofsky, B. A. , McNamara, K. L. , Brandstetter, K. A. , Walton, Z. E. , Gu, T. L. , Silva, J. C. , Crosby, K. , Shapiro, G. I. , Maira, S. M. , Ji, H. , Castrillon, D. H. , Kim, C. F. , García-Echeverría, C. & 6 others Bardeesy, N., Sharpless, N. E., Hayes, N. D., Kim, W. Y., Engelman, J. A. & Wong, K. K. Jun 15 2010 In : Cancer Cell. 17, 6, p. 547-559 13 p.

Research output: Contribution to journalArticle

Proteomics
Lung
Neoplasms
Penetrance
Phosphoproteins
139 Citations

Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma

Cowey, C. L., Amin, C., Pruthi, R. S., Wallen, E. M., Nielsen, M. E., Grigson, G., Watkins, C., Nance, K. V., Crane, J., Jalkut, M., Moore, D. T., Kim, W. Y., Godley, P. A., Whang, Y. E., Fielding, J. R. & Rathmell, W. K. Mar 20 2010 In : Journal of Clinical Oncology. 28, 9, p. 1502-1507 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Clinical Trials
Nephrectomy
Neoplasms
Therapeutics
2009
92 Citations

HIF2α cooperates with RAS to promote lung tumorigenesis in mice

Kim, W. Y., Perera, S., Zhou, B., Carretero, J., Jen, J. Y., Heathcote, S. A., Jackson, A. L., Nikolinakos, P., Ospina, B., Naumov, G., Brandstetter, K. A., Weigman, V. J., Zaghlul, S., Hayes, D. N., Padera, R. F., Heymach, J. V., Kung, A. L., Sharpless, N. E., Kaelin, W. G. & Wong, K. K. Aug 3 2009 In : Journal of Clinical Investigation. 119, 8, p. 2160-2170 11 p.

Research output: Contribution to journalArticle

Carcinogenesis
Lung
Epithelial-Mesenchymal Transition
Non-Small Cell Lung Carcinoma
Neoplasms
1 Citations

HIF2α cooperates with RAS to promote lung tumorigenesis in mice (Journal of Clinical Investigation (2009) 119, (2160-2170) doi: 101172/JCI38443)

Kim, W. Y., Perera, S., Zhou, B., Carretero, J., Yeh, J. J., Heathcote, S. A., Jackson, A. L., Nikolinakos, P., Ospina, B., Naumov, G. N., Brandstetter, K. A., Weigman, V. J., Zaghlul, S., Hayes, D. N., Padera, R. F., Heymach, J. V., Kung, A. L., Sharpless, N. E., Kaelin, W. G. & Wong, K. K. Oct 1 2009 In : Journal of Clinical Investigation. 119, 10, p. 3182 1 p.

Research output: Contribution to journalComment/debate

Carcinogenesis
Lung

Modulation of protein stability: Targeting the VHL pathway

Kim, W. Y. & Kaelin, W. G. 2009 Modulation of Protein Stability in Cancer Therapy. Springer US, p. 45-63 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Von Hippel-Lindau Tumor Suppressor Protein
Protein Stability
Protein Transport
Ligases
Ubiquitin

Molecular responses to hypoxia: Ancient pathways, clinical promises

Kim, W. Y. & Ivan, M. Sep 2009 In : Journal of Cellular and Molecular Medicine. 13, 9 A, p. 2757-2758 2 p.

Research output: Contribution to journalEditorial

Hypoxia-Inducible Factor 1
Cell Hypoxia
Critical Pathways
Signal Transduction
Medicine
114 Citations

Regulation of endocytosis via the oxygen-sensing pathway

Wang, Y., Roche, O., Yan, M. S., Finak, G., Evans, A. J., Metcalf, J. L., Hast, B. E., Hanna, S. C., Wondergem, B., Furge, K. A., Irwin, M. S., Kim, W. Y., Teh, B. T., Grinstein, S., Park, M., Marsden, P. A. & Ohh, M. Mar 1 2009 In : Nature Medicine. 15, 3, p. 319-325 7 p.

Research output: Contribution to journalArticle

Endocytosis
Tumors
Receptor Protein-Tyrosine Kinases
Oxygen
Chemical activation
2008
35 Citations

mTOR pathway in renal cell carcinoma

Hann, S. C., Heathcote, S. A. & Kim, W. Y. Feb 1 2008 In : Expert Review of Anticancer Therapy. 8, 2, p. 283-292 10 p.

Research output: Contribution to journalReview article

Renal Cell Carcinoma
Therapeutics
Therapeutic Uses
Vascular Endothelial Growth Factor A
Histology
6 Citations

VHL Inactivation: A New Road to Senescence

Kim, W. Y. & Sharpless, N. E. Apr 8 2008 In : Cancer Cell. 13, 4, p. 295-297 3 p.

Research output: Contribution to journalShort survey

Neoplasms
Tumor Suppressor Genes
Cell Biology
Transcription Factors
2007
59 Citations

CD200 is induced by ERK and is a potential therapeutic target in melanoma

Petermann, K. B., Rozenberg, G. I., Zedek, D., Groben, P., McKinnon, K., Buehler, C., Kim, W. Y., Shields, J. M., Penland, S., Bear, J. E., Thomas, N. E., Serody, J. S. & Sharpless, N. E. Dec 2007 In : Journal of Clinical Investigation. 117, 12, p. 3922-3929 8 p.

Research output: Contribution to journalArticle

Melanoma
Therapeutics
Immunomodulation
Mitogen-Activated Protein Kinase Kinases
Microarray Analysis
43 Citations

Dexamethasone-induced posterior reversible encephalopathy syndrome

Irvin, W., MacDonald, G., Smith, J. K. & Kim, W. Y. Jun 10 2007 In : Journal of Clinical Oncology. 25, 17, p. 2484-2486 3 p.

Research output: Contribution to journalArticle

Hypertensive Encephalopathy
Posterior Leukoencephalopathy Syndrome
Trazodone
Pyridines
X Ray Computed Tomography
54 Citations

Dominant-negative HIF-3α4 suppresses VHL-null renal cell carcinoma progression

Maynard, M. A., Evans, A. J., Shi, W., Kim, W. Y., Liu, F. F. & Ohh, M. Nov 15 2007 In : Cell Cycle. 6, 22, p. 2810-2816 7 p.

Research output: Contribution to journalArticle

Null Lymphocytes
Renal Cell Carcinoma
Tumors
Cells
Mutation