• 1972 Citations
  • 21 h-Index
19962019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Phosphotransferases Medicine & Life Sciences
Orphan Nuclear Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Protein Kinase Inhibitors Chemical Compounds
Protein Kinases Medicine & Life Sciences
Molecules Chemical Compounds
Assays Chemical Compounds

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Research Output 1996 2019

  • 1972 Citations
  • 21 h-Index
  • 45 Article
  • 4 Comment/debate
  • 3 Review article
  • 1 Chapter

CHAPTER 2: New Screening Approaches for Kinases

Drewry, D. H., King, B. W., Wells, C. I. & Zuercher, W. J., Jan 1 2019, Therapies for Retinal Degeneration: Targeting Common Processes. Ward, R. A. & Goldberg, F. W. (eds.). 67 ed. Royal Society of Chemistry, p. 9-33 25 p. (RSC Drug Discovery Series; vol. 2019-January, no. 67).

Research output: Chapter in Book/Report/Conference proceedingChapter

Phosphotransferases
Technology
Fluorometry
Drug Discovery
Gene Library
1 Citations

1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) Inhibitors

Asquith, C. R. M., Godoi, P. H., Cou ago, R. M., Laitinen, T., Scott, J. W., Langendorf, C. G., Oakhill, J. S., Drewry, D. H., Zuercher, W. J., Koutentis, P. A., Willson, T. M. & Kalogirou, A. S., Jan 1 2018, In : Molecules. 23, 5, 1221.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Kinase
Thiadiazoles
X ray crystallography
Protein Kinase Inhibitors
Molecular structure

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

Krulikas, L. J., McDonald, I. M., Lee, B., Okumu, D. O., East, M. P., Gilbert, T. S. K., Herring, L. E., Golitz, B. T., Wells, C. I., Axtman, A. D., Zuercher, W. J., Willson, T. M., Kireev, D., Yeh, J. J., Johnson, G. L., Baines, A. T. & Graves, L. M., Sep 1 2018, In : SLAS Discovery. 23, 8, p. 850-861 12 p.

Research output: Contribution to journalArticle

gemcitabine
Preclinical Drug Evaluations
Cell growth
Pancreatic Neoplasms
Screening

Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells

Foulkes, D. M., Byrne, D. P., Yeung, W., Shrestha, S., Bailey, F. P., Ferries, S., Eyers, C. E., Keeshan, K., Wells, C., Drewry, D. H., Zuercher, W. J., Kannan, N. & Eyers, P. A., Sep 25 2018, In : Science Signaling. 11, 549, aat7951.

Research output: Contribution to journalArticle

Corrosion inhibitors
Protein Kinases
Cells
Degradation
Pharmaceutical Preparations
1 Citations

GW779439X and its pyrazolopyridazine derivatives inhibit the serine/threonine kinase Stk1 and act as antibiotic adjuvants against β-lactam-resistant Staphylococcus aureus

Schaenzer, A. J., Wlodarchak, N., Drewry, D., Zuercher, W. J., Rose, W. E., Ferrer, C. A., Sauer, J. D. & Striker, R., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
beta-Lactams
Staphylococcus aureus
Phosphotransferases
Methicillin-Resistant Staphylococcus aureus