Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
Ligands Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Drug Receptors Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 2007 2017

Research Output 1974 2017

5 Citations

Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor

Nguyen, T., Li, J. X., Thomas, B. F., Wiley, J. L., Kenakin, T. P. & Zhang, Y. May 1 2017 In : Medicinal Research Reviews. 37, 3, p. 441-474 34 p.

Research output: Research - peer-reviewReview article

Cannabinoid Receptor CB1
Pharmacology
Ligands
Therapeutics
Allosteric Site

A new molecular mechanism to engineer protean agonism at a G protein-coupled receptor

De Min, A., Matera, C., Bock, A., Holze, J., Kloeckner, J., Muth, M., Traenkle, C., De Amici, M., Kenakin, T., Holzgrabe, U., Dallanoce, C., Kostenis, E., Mohr, K. & Schrage, R. Apr 1 2017 In : Molecular Pharmacology. 91, 4, p. 348-356 9 p.

Research output: Research - peer-reviewArticle

G-Protein-Coupled Receptors
Cholinergic Receptors
Cholinergic Agents
Ligands
Molecular Probes

CHAPTER 2: Identifying and Quantifying Allosteric Drug Function

Kenakin, T. 2017 Allosterism in Drug Discovery. 56 ed. Royal Society of Chemistry, Vol. 2017-January, p. 24-39 16 p. (RSC Drug Discovery Series; vol. 2017-January, no. 56)

Research output: ResearchChapter

Ligands
Pharmaceutical Preparations
Permissiveness
Pindolol
Propranolol
1 Citations

Signaling bias in drug discovery

Kenakin, T. Apr 3 2017 In : Expert Opinion on Drug Discovery. 12, 4, p. 321-333 13 p.

Research output: Research - peer-reviewReview article

Drug Discovery
Therapeutics
Pharmacology
In Vitro Techniques
Expert Testimony
12 Citations

A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor

Grundmann, M., Tikhonova, I. G., Hudson, B. D., Smith, N. J., Mohr, K., Ulven, T., Milligan, G., Kenakin, T. & Kostenis, E. Mar 17 2016 In : Cell Chemical Biology. 23, 3, p. 392-403 12 p.

Research output: Research - peer-reviewArticle

G-Protein-Coupled Receptors
Pharmacology
Ligands
Chemical activation
Cell Tracking