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  • 2 Similar Profiles
Derivatives Chemical Compounds
Antineoplastic Agents Medicine & Life Sciences
Cells Chemical Compounds
Neoplasms Medicine & Life Sciences
Cell Line Medicine & Life Sciences
HIV Medicine & Life Sciences
In Vitro Techniques Medicine & Life Sciences
Anti-HIV Agents Medicine & Life Sciences

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Projects 1992 2019

Research Output 1982 2017

  • 5194 Citations
  • 37 h-Index
  • 150 Article
  • 20 Review article
  • 3 Comment/debate
  • 1 Chapter
1 Citations

Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives

Zhu, G. X., Cheng, P. L., Goto, M., Zhang, N., Morris-Natschke, S. L., Hsieh, K. Y., Yang, G. Z., Yang, Q. R., Liu, Y. Q., Chen, H. L., Zhang, X. S. & Lee, K. H. 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 8, p. 1750-1753 4 p.

Research output: Research - peer-reviewArticle

Camptothecin
Derivatives
Cytotoxicity
Cells
irinotecan
Staurosporine
Pharmaceutical Chemistry
Protein-Tyrosine Kinases
Paclitaxel
Publications
3 Citations

Synthesis and biological evaluation of chalcone, dihydrochalcone, and 1,3-diarylpropane analogs as anti-inflammatory agents

Vijaya Bhaskar Reddy, M., Hung, H. Y., Kuo, P. C., Huang, G. J., Chan, Y. Y., Huang, S. C., Wu, S. J., Morris-Natschke, S. L., Lee, K. H. & Wu, T. S. 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 7, p. 1547-1550 4 p.

Research output: Research - peer-reviewArticle

Chalcones
Lead compounds
Chalcone
Macrophages
Condensation
2 Citations

Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release

Xin, G., Wei, Z., Ji, C., Zheng, H., Gu, J., Ma, L., Huang, W., Morris-Natschke, S. L., Yeh, J. L., Zhang, R., Qin, C., Wen, L., Xing, Z., Cao, Y., Xia, Q., Li, K., Niu, H., Lee, K. H. & Huang, W. Jul 1 2017 In : Free Radical Biology and Medicine. 108, p. 247-257 11 p.

Research output: Research - peer-reviewArticle

Humulus
Platelet Activation
Mitochondrial DNA
Thrombosis
Hemorrhage
2 Citations

(+)-(14β)-14-Ethylmatridin-15-one, a New Quinolizidine Alkaloid from the Poisonous Plant Oxytropis ochrocephala Bunge

Tan, C. J., Yi, P., Goto, M., Morris-Natschke, S. L., Liu, L. N., Lee, K. H. & Zhao, B. Y. Mar 1 2016 In : Helvetica Chimica Acta. 99, 3, p. 225-227 3 p.

Research output: Research - peer-reviewArticle

Quinolizidines
Alkaloids
Nuclear magnetic resonance
Derivatives
Experiments