• 6427 Citations
  • 40 h-Index
1985 …2019
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  • 5 Similar Profiles
Lysine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Histones Medicine & Life Sciences
Ligands Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 1997 2019

Research Output 1985 2018

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency

Hopcraft, S. E., Pattenden, S. G., James, L. I., Frye, S. V., Dittmer, D. P. & Damania, B. A., Sep 1 2018, In : PLoS pathogens. 14, 9, e1007267.

Research output: Contribution to journalArticle

Human Herpesvirus 8
Chromatin Assembly and Disassembly
Epigenomics
Polycomb Repressive Complex 1
Histone Code

Highly Selective MERTK Inhibitors Achieved by a Single Methyl Group

Zhao, J., Zhang, D., Zhang, W., Stashko, M. A., DeRyckere, D., Vasileiadi, E., Parker, R. E., Hunter, D., Liu, Q., Zhang, Y., Norris-Drouin, J., Li, B., Drewry, D. H., Kireev, D., Graham, D. K., Earp, H. S., Frye, S. V. & Wang, X., Nov 21 2018, In : Journal of medicinal chemistry. 61, 22, p. 10242-10254 13 p.

Research output: Contribution to journalArticle

Phosphotransferases
Adenosine Triphosphate
Bone Marrow Cells
Leukemia
Pharmacokinetics
2 Citations

MerTK as a therapeutic target in glioblastoma: Neuro Oncol

Wu, J., Frady, L. N., Bash, R. E., Cohen, S. M., Schorzman, A. N., Su, Y. T., Irvin, D. M., Zamboni, W. C., Wang, X., Frye, S. V., Ewend, M. G., Sulman, E. P., Gilbert, M. R., Earp, H. S. & Miller, C. R., Jun 13 2018, In : Neuro-Oncology. 20, 1, p. 92-102 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Macrophages
Neoplasms
Therapeutics
UNC2025

MERTK Mediates Intrinsic and Adaptive Resistance to AXL-targeting Agents

McDaniel, N. K., Cummings, C. T., Iida, M., Hülse, J., Pearson, H. E., Vasileiadi, E., Parker, R. E., Orbuch, R. A., Ondracek, O. J., Welke, N. B., Kang, G. H., Davies, K. D., Wang, X., Frye, S. V., Earp, H. S., Harari, P. M., Kimple, R. J., DeRyckere, D., Graham, D. K. & Wheeler, D. L., Nov 1 2018, In : Molecular cancer therapeutics. 17, 11, p. 2297-2308 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Neoplasms
Non-Small Cell Lung Carcinoma
Survival
Receptor Protein-Tyrosine Kinases

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1

Suh, J. L., Watts, B., Stuckey, J. I., Norris-Drouin, J. L., Cholensky, S. H., Dickson, B. M., An, Y., Mathea, S., Salah, E., Knapp, S., Khan, A., Adams, A. T., Strahl, B. D., Sagum, C. A., Bedford, M. T., James, L. I., Kireev, D. B. & Frye, S. V., Apr 10 2018, In : Biochemistry. 57, 14, p. 2140-2149 10 p.

Research output: Contribution to journalArticle

Transcription Factor TFIID
Peptide Initiation Factors
Transcription
Ligands
Proteins