Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Lysine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Histones Medicine & Life Sciences
Ligands Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Azasteroids Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 1997 2019

Research Output 1985 2018

MerTK as a therapeutic target in glioblastoma: Neuro Oncol

Wu, J., Frady, L. N., Bash, R. E., Cohen, S. M., Schorzman, A. N., Su, Y. T., Irvin, D. M., Zamboni, W. C., Wang, X., Frye, S. V., Ewend, M. G., Sulman, E. P., Gilbert, M. R., Earp, H. S. & Miller, C. R. Jun 13 2018 In : Neuro-Oncology. 20, 1, p. 92-102 11 p.

Research output: Contribution to journalArticle

2 Citations

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors

McIver, A. L., Zhang, W., Liu, Q., Jiang, X., Stashko, M. A., Nichols, J., Miley, M. J., Norris-Drouin, J., Machius, M., DeRyckere, D., Wood, E., Graham, D. K., Earp, H. S., Kireev, D., Frye, S. V. & Wang, X. Jan 1 2017 In : ChemMedChem. 12, 3, p. 207-213 7 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Enzyme-Linked Immunosorbent Assay
5 Citations

UNC2025, a MERTK small-molecule inhibitor, is therapeutically effective alone and in combination with methotrexate in leukemia models

DeRyckere, D., Lee-Sherick, A. B., Huey, M. G., Hill, A. A., Tyner, J. W., Jacobsen, K. M., Page, L. S., Kirkpatrick, G. G., Eryildiz, F., Montgomery, S. A., Zhang, W., Wang, X., Frye, S. V., Earp, H. S. & Graham, D. K. Mar 15 2017 In : Clinical Cancer Research. 23, 6, p. 1481-1492 12 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
2 Citations

A high-throughput screening-compatible strategy for the identification of inositol pyrophosphate kinase inhibitors

Baughman, B. M., Wang, H., An, Y., Kireev, D., Stashko, M. A., Jessen, H. J., Pearce, K. H., Frye, S. V. & Shears, S. B. Oct 1 2016 In : PLoS ONE. 11, 10, e0164378

Research output: Contribution to journalArticle

probes (equipment)
inositol phosphates
6 Citations

Chemical probes for methyl lysine reader domains

James, L. I. & Frye, S. V. Jan 1 2016 In : Current Opinion in Chemical Biology. 33, p. 135-141 7 p.

Research output: Contribution to journalReview article