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  • 12 Similar Profiles
Proteins Medicine & Life Sciences
ras Proteins Medicine & Life Sciences
Cysteine Medicine & Life Sciences
Chemical activation Chemical Compounds
Guanine Nucleotides Medicine & Life Sciences
Nuclear magnetic resonance Chemical Compounds
Growth Medicine & Life Sciences
Actins Medicine & Life Sciences

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Projects 1981 2017

Research Output 1984 2017

A KRAS GTPase K104Q mutant retains downstream signaling by offsetting defects in regulation

Yin, G., Kistler, S., George, S. D., Kuhlmann, N., Garvey, L., Huynh, M., Bagni, R. K., Lammers, M., Der, C. J. & Campbell, S. L. Mar 17 2017 In : Journal of Biological Chemistry. 292, 11, p. 4446-4456 11 p.

Research output: Research - peer-reviewArticle

Guanine Nucleotide Exchange Factors
GTP Phosphohydrolases
Defects
GTPase-Activating Proteins
Acetylation
2 Citations

A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization

Thompson, P. M., Ramachandran, S., Case, L. B., Tolbert, C. E., Tandon, A., Pershad, M., Dokholyan, N. V., Waterman, C. M. & Campbell, S. L. Feb 7 2017 In : Structure. 25, 2, p. 264-275 12 p.

Research output: Research - peer-reviewArticle

Vinculin
Structural Models
Membranes
Focal Adhesions
Lipid Bilayers

Getting a Handle on RAS-targeted therapies: Cysteine directed inhibitors

Huynh, M. V. & Campbell, S. L. Mar 1 2016 In : Mini-Reviews in Medicinal Chemistry. 16, 5, p. 383-390 8 p.

Research output: Research - peer-reviewArticle

Cysteine
Therapeutics
Oncogenes
Oxidation-Reduction
Proteins
4 Citations

The Structural Basis of Actin Organization by Vinculin and Metavinculin

Kim, L. Y., Thompson, P. M., Lee, H. T., Pershad, M., Campbell, S. L. & Alushin, G. M. Jan 16 2016 In : Journal of Molecular Biology. 428, 1, p. 10-25 16 p.

Research output: Research - peer-reviewArticle

Vinculin
Actins
metavinculin
Cryoelectron Microscopy
Cadherins
57 Citations

Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

Case, L. B., Baird, M. A., Shtengel, G., Campbell, S. L., Hess, H. F., Davidson, M. W. & Waterman, C. M. Jul 2 2015 In : Nature Cell Biology. 17, 7, p. 880-892 13 p.

Research output: Research - peer-reviewArticle

Vinculin
Focal Adhesions
Proteins
Talin
Paxillin