• 6656 Citations
  • 43 h-Index
1981 …2017
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  • 11 Similar Profiles
ras Proteins Medicine & Life Sciences
Vinculin Medicine & Life Sciences
Guanine Nucleotides Medicine & Life Sciences
Guanine Nucleotide Exchange Factors Medicine & Life Sciences
Cysteine Medicine & Life Sciences
Actins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Focal Adhesions Medicine & Life Sciences

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Projects 1981 2017

Research Output 1984 2017

1 Citations

A KRAS GTPase K104Q mutant retains downstream signaling by offsetting defects in regulation

Yin, G., Kistler, S., George, S. D., Kuhlmann, N., Garvey, L., Huynh, M., Bagni, R. K., Lammers, M., Der, C. J. & Campbell, S. L., Mar 17 2017, In : Journal of Biological Chemistry. 292, 11, p. 4446-4456 11 p.

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
GTP Phosphohydrolases
GTPase-Activating Proteins
Defects
Acetylation
3 Citations

A Structural Model for Vinculin Insertion into PIP2-Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization

Thompson, P. M., Ramachandran, S., Case, L. B., Tolbert, C. E., Tandon, A., Pershad, M., Dokholyan, N. V., Waterman, C. M. & Campbell, S. L., Feb 7 2017, In : Structure. 25, 2, p. 264-275 12 p.

Research output: Contribution to journalArticle

Vinculin
Structural Models
Focal Adhesions
Membranes
Lipid Bilayers

RAS ubiquitylation modulates effector interactions

Thurman, R., Siraliev-Perez, E. & Campbell, S. L., Nov 24 2017, (Accepted/In press) In : Small GTPases. p. 1-6 6 p.

Research output: Contribution to journalArticle

Signal transduction
GTPase-Activating Proteins
Phosphatidylinositols
Guanosine Triphosphate
p120 GTPase Activating Protein

Getting a Handle on RAS-targeted therapies: Cysteine directed inhibitors

Huynh, M. V. & Campbell, S. L., Mar 1 2016, In : Mini-Reviews in Medicinal Chemistry. 16, 5, p. 383-390 8 p.

Research output: Contribution to journalArticle

Cysteine
Oncogenes
Oxidation-Reduction
Therapeutics
Proteins
10 Citations

The Structural Basis of Actin Organization by Vinculin and Metavinculin

Kim, L. Y., Thompson, P. M., Lee, H. T., Pershad, M., Campbell, S. L. & Alushin, G. M., Jan 16 2016, In : Journal of Molecular Biology. 428, 1, p. 10-25 16 p.

Research output: Contribution to journalArticle

Vinculin
Actins
Cryoelectron Microscopy
Cadherins
metavinculin