• 22895 Citations
  • 75 h-Index
1981 …2019
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  • 9 Similar Profiles
Inflammation Medicine & Life Sciences
Colitis Medicine & Life Sciences
Inflammatory Bowel Diseases Medicine & Life Sciences
Crohn Disease Medicine & Life Sciences
Interleukin-10 Medicine & Life Sciences
Peptidoglycan Medicine & Life Sciences
Enterocolitis Medicine & Life Sciences
Bacteria Medicine & Life Sciences

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Projects 1989 2019

Germ-Free Life
Rodentia
Research Personnel
Organized Financing
Microbiota
Gastrointestinal Diseases
Research
Inflammatory Bowel Diseases
Research Personnel
Biostatistics
rifaximin
Fibrosis
Hepatic Encephalopathy
Bile Acids and Salts
Germ-Free Life

Research Output 1981 2018

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3

Zhang, C. J. , Wang, C. , Jiang, M. , Gu, C. , Xiao, J. , Chen, X. , Martin, B. N. , Tang, F. , Yamamoto, E. , Xian, Y. , Wang, H. , Li, F. , Sartor, R. B. , Smith, H. , Husni, M. E. , Shi, F. D. , Gao, J. , Carman, J. , Dongre, A. , McKarns, S. C. & 4 others Coppieters, K., Jørgensen, T. N., Leonard, W. J. & Li, X., Dec 1 2018, In : Nature Communications. 9, 1, 2745

Research output: Contribution to journalArticle

regulators
B-Lymphocytes
Cells
T-Lymphocytes
mice
1 Citations

A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells

Chang, Y. L., Rossetti, M., Vlamakis, H., Casero, D., Sunga, G., Harre, N., Miller, S., Humphries, R., Stappenbeck, T., Simpson, K. W., Sartor, R. B., Wu, G., Lewis, J., Bushman, F., McGovern, D. P. B., Salzman, N., Borneman, J., Xavier, R., Huttenhower, C. & Braun, J., Apr 25 2018, (Accepted/In press) In : Mucosal Immunology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Crohn Disease
T-Lymphocytes
Energy Metabolism
Interleukin-17
Allergy and Immunology

Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses

Iyer, S. S., Gensollen, T., Gandhi, A., Oh, S. F., Neves, J. F., Collin, F., Lavin, R., Serra, C., Glickman, J., de Silva, P. S. A., Sartor, R. B., Besra, G., Hauser, R., Maxwell, A., Llebaria, A. & Blumberg, R. S., May 17 2018, In : Cell. 173, 5, p. 1123-1134.e11

Research output: Contribution to journalArticle

Oxazoles
Aryl Hydrocarbon Receptors
Inflammation
Natural Killer T-Cells
Epithelial Cells
1 Citations

Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice

Rogala, A. R., Schoenborn, A. A., Fee, B. E., Cantillana, V. A., Joyce, M. J., Gharaibeh, R. Z., Roy, S., Fodor, A. A., Balfour Sartor, R., Taylor, G. A. & Gulati, A. S., Feb 1 2018, In : DMM Disease Models and Mechanisms. 11, 2

Research output: Contribution to journalArticle

Paneth Cells
Inflammatory Bowel Diseases
Unsaturated polymers
Specific Pathogen-Free Organisms
Inflammation

Fecal and Mucosa-Associated Intestinal Microbiota in Patients with Diarrhea-Predominant Irritable Bowel Syndrome

Maharshak, N., Ringel, Y., Katibian, D., Lundqvist, A., Sartor, R. B., Carroll, I. M. & Ringel-Kulka, T., May 17 2018, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-10 10 p.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Diarrhea
Mucous Membrane
Microbiota
Gastrointestinal Microbiome