• 5257 Citations
  • 38 h-Index
1975 …2020
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  • 2 Similar Profiles
Penicillin-Binding Proteins Medicine & Life Sciences
Neisseria gonorrhoeae Medicine & Life Sciences
Purinergic P2Y1 Receptors Medicine & Life Sciences
Escherichia coli Chemical Compounds
Penicillins Medicine & Life Sciences
Mutation Medicine & Life Sciences
Type C Phospholipases Medicine & Life Sciences
beta-Lactams Medicine & Life Sciences

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Projects 1975 2020

Research Output 1978 2018

  • 5257 Citations
  • 38 h-Index
  • 107 Article
  • 4 Review article
  • 1 Chapter
  • 1 Letter
1 Citations

In vivo-selected compensatory mutations restore the fitness cost of mosaic penA Alleles that confer ceftriaxone resistance in Neisseria gonorrhoeae

Vincent, L. R., Kerr, S. R., Tan, Y., Tomberg, J., Raterman, E. L., Dunning Hotopp, J. C., Unemo, M., Nicholas, R. A. & Jerse, A. E., Mar 1 2018, In : mBio. 9, 2, e01905-17.

Research output: Contribution to journalArticle

Aconitate Hydratase
Ceftriaxone
Neisseria gonorrhoeae
Microbial Drug Resistance
Alleles

Properly folded and functional PorB from Neisseria gonorrhoeae inhibits dendritic cell stimulation of CD4+ T cell proliferation

Zhu, W., Tomberg, J., Knilans, K. J., Anderson, J. E., McKinnon, K. P., Sempowski, G. D., Nicholas, R. A. & Duncan, J. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 28, p. 11218-11229 12 p.

Research output: Contribution to journalArticle

T-cells
Neisseria gonorrhoeae
Cell proliferation
Dendritic Cells
Toll-Like Receptor 2
3 Citations

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness

Tomberg, J., Fedarovich, A., Vincent, L. R., Jerse, A. E., Unemo, M., Davies, C. & Nicholas, R. A., Feb 28 2017, In : Biochemistry. 56, 8, p. 1140-1150 11 p.

Research output: Contribution to journalArticle

Cephalosporin Resistance
Penicillin-Binding Proteins
Cephalosporins
Alanine
Mutation
3 Citations

Control of gdhR expression in Neisseria gonorrhoeae via autoregulation and a master repressor (MtrR) of a drug efflux pump operon

Rouquette-Loughlin, C. E., Zalucki, Y. M., Dhulipala, V. L., Balthazar, J. T., Doyle, R. G., Nicholas, R. A., Begum, A. A., Raterman, E. L., Jerse, A. E. & Shafer, W. M., Mar 1 2017, In : mBio. 8, 2, e00449-17.

Research output: Contribution to journalArticle

Neisseria meningitidis
Neisseria gonorrhoeae
Operon
Homeostasis
Pharmaceutical Preparations
1 Citations

Synthesis and Kinetic Analysis of Two Conformationally Restricted Peptide Substrates of Escherichia coli Penicillin-Binding Protein 5

Nemmara, V. V., Nicholas, R. A. & Pratt, R. F., Jul 26 2016, In : Biochemistry. 55, 29, p. 4065-4076 12 p.

Research output: Contribution to journalArticle

Penicillin-Binding Proteins
Escherichia coli Proteins
Escherichia coli
Cyclic Peptides
Peptidoglycan