Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Chemical and Drug Induced Liver Injury Medicine & Life Sciences
Cytochrome P-450 CYP3A Medicine & Life Sciences
Liver Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Breath Tests Medicine & Life Sciences
Erythromycin Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Acetaminophen Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1986 2018

North Carolina Translational & Clinical Sciences Institute (NC TraCS)

Fraser, M. W., Wohl, D. A., Weber, D. J., Bangdiwala, S. I., Carey, T. S., Phillips, C. L., Miller, W. C., Jonsson-Funk, M. L., Jones, S. W., Beck, J. D., Mauriello, S. M., Retsch-Bogart, G. Z., Falk, R. J., Jordan, J. M., Ammerman, A. S., Carpenter, W. R., Edwards, L. J., Garrett, J. M., Coyne-Beasley, T., Henderson, G. E., Stewart, P. W., Davis, A. M., Evans, J. P., Gilmore, J. H., Gaynes, B. N., Brookhart, M. A., Sleath, B. L., Offenbacher, S., Marzluff, W. F., Topal, M. D., Orringer, E. P., Qaqish, B. F., Leigh, M. W., Peden, D. B., Buse, J. B., Tolleson-Rinehart, S., Ransohoff, D. F., Funkhouser, W. K., Egan, T. M., Cai, J., Truong, K. N., Brouwer, K. L., Boucher, R. C., Sen, P. K., Reuland, D. S., Donahue, K. E., Weiner, B. J., Watkins, P. B., Lin, W., Perrin, E. M., Magnuson, T. R., Corbie-Smith, G. M., Duncan, J. A., Weinberger, M., Zeng, D., Meshnick, S. R., Ibrahim, J. G., Dilworth-Anderson, P., Johnson, G. L., Walker, R. L., Viera, A. J., Glickman, S. W., Halladay, J. R., Rennie, S. M., Key, N. S., Rubin, J. E., Kosorok, M. R., Zhu, H., Bair, E., Henning, S. J., Mackman, N., Fine, J. P., Mayer-Davis, E. J., Stuermer, T. H. R., Davis, R. M., Park, S. I., Wu, M. C., Carpenter, D. M., Fang, G., Weaver, M. A., Lin, F., Davis, S. M., Shea, C. M., Carter-Edwards, L., Dennis, A. M., Fisher, J. A., Golightly, Y. M., Hingtgen, S. D., Smith, A. M., Tan, J. T., Asher, G. N., Barritt, A. S., Blouin, R., Buchbinder, M., Hurt, C., Juengst, E. T., Mendoza, L. C., Reeve, B., Roman Isler, M. D., Wood, W. A., Ahalt, S., Agans, R. P., Dave, G. J., Zhou, H., Skinner, A. C., Wilhelmsen, K. C., Song, L., Fischer, W. A., Peery, A. F., Powers, K. A., Sims, C. E., Mostafa, J., Lightfoot, A. F., Ryan, A. E., Otey, C. A., Donaldson, S. H., Leeman, J., Kashuba, A. D., Gomez, S. M., Chung, A. E., Meyer, A. M., Parrott, M. C., Toles, M. P., Schmitt, C., Nichols, H. B. & Moran, T. P.

NIH National Center for Advancing Translational Sciences (NCATS)

9/26/134/30/18

Project: Research project

Annual Reports

North Carolina Translational & Clinical Sciences Institute (NC TraCS)

Fraser, M. W., Sims, C. E., Mostafa, J., Wohl, D. A., Weber, D. J., Bangdiwala, S. I., Carey, T. S., Phillips, C. L., Miller, W. C., Jonsson-Funk, M. L., Jones, S. W., Beck, J. D., Mauriello, S. M., Retsch-Bogart, G. Z., Falk, R. J., Jordan, J. M., Ammerman, A. S., Carpenter, W. R., Edwards, L. J., Garrett, J. M., Coyne-Beasley, T., Henderson, G. E., Stewart, P. W., Davis, A. M., Evans, J. P., Gilmore, J. H., Gaynes, B. N., Brookhart, M. A., Sleath, B. L., Offenbacher, S., Marzluff, W. F., Topal, M. D., Orringer, E. P., Qaqish, B. F., Leigh, M. W., Peden, D. B., Buse, J. B., Tolleson-Rinehart, S., Ransohoff, D. F., Funkhouser, W. K., Egan, T. M., Cai, J., Truong, K. N., Brouwer, K. L., Boucher, R. C., Sen, P. K., Reuland, D. S., Donahue, K. E., Weiner, B. J., Watkins, P. B., Lin, W., Perrin, E. M., Magnuson, T. R., Corbie-Smith, G. M., Duncan, J. A., Weinberger, M., Zeng, D., Meshnick, S. R., Ibrahim, J. G., Dilworth-Anderson, P., Johnson, G. L., Walker, R. L., Viera, A. J., Glickman, S. W., Halladay, J. R., Rennie, S. M., Key, N. S., Rubin, J. E., Kosorok, M. R., Zhu, H., Bair, E., Henning, S. J., Mackman, N., Fine, J. P., Mayer-Davis, E. J., Stuermer, T. H. R., Davis, R. M., Park, S. I., Wu, M. C., Carpenter, D. M., Fang, G., Weaver, M. A., Lin, F., Davis, S. M., Shea, C. M., Carter-Edwards, L., Dennis, A. M., Fisher, J. A., Golightly, Y. M., Hingtgen, S. D., Smith, A. M., Tan, J. T., Asher, G. N., Barritt, A. S., Blouin, R., Buchbinder, M., Hurt, C., Juengst, E. T., Mendoza, L. C., Reeve, B., Roman Isler, M. D., Wood, W. A., Ahalt, S., Agans, R. P., Dave, G. J., Lightfoot, A. F., Zhou, H., Skinner, A. C., Wilhelmsen, K. C., Song, L., Fischer, W. A., Peery, A. F., Powers, K. A., Ryan, A. E., Otey, C. A., Donaldson, S. H., Leeman, J., Kashuba, A. D., Gomez, S. M., Chung, A. E., Meyer, A. M., Parrott, M. C., Toles, M. P., Schmitt, C., Nichols, H. B. & Moran, T. P.

NIH National Center for Advancing Translational Sciences (NCATS)

9/26/134/30/18

Project: Research project

Annual Reports

North Carolina Translational & Clinical Sciences Institute (NC TraCS)

Fraser, M. W., Sims, C. E., Mostafa, J., Wohl, D. A., Weber, D. J., Bangdiwala, S. I., Carey, T. S., Phillips, C. L., Miller, W. C., Jonsson-Funk, M. L., Jones, S. W., Beck, J. D., Mauriello, S. M., Retsch-Bogart, G. Z., Falk, R. J., Jordan, J. M., Ammerman, A. S., Carpenter, W. R., Edwards, L. J., Garrett, J. M., Coyne-Beasley, T., Henderson, G. E., Stewart, P. W., Davis, A. M., Evans, J. P., Gilmore, J. H., Gaynes, B. N., Brookhart, M. A., Sleath, B. L., Offenbacher, S., Marzluff, W. F., Topal, M. D., Orringer, E. P., Qaqish, B. F., Leigh, M. W., Peden, D. B., Buse, J. B., Tolleson-Rinehart, S., Ransohoff, D. F., Funkhouser, W. K., Egan, T. M., Cai, J., Truong, K. N., Brouwer, K. L., Boucher, R. C., Sen, P. K., Reuland, D. S., Donahue, K. E., Weiner, B. J., Watkins, P. B., Lin, W., Perrin, E. M., Magnuson, T. R., Corbie-Smith, G. M., Duncan, J. A., Weinberger, M., Zeng, D., Meshnick, S. R., Ibrahim, J. G., Dilworth-Anderson, P., Johnson, G. L., Walker, R. L., Viera, A. J., Glickman, S. W., Halladay, J. R., Rennie, S. M., Key, N. S., Rubin, J. E., Kosorok, M. R., Zhu, H., Bair, E., Henning, S. J., Mackman, N., Fine, J. P., Mayer-Davis, E. J., Stuermer, T. H. R., Davis, R. M., Park, S. I., Wu, M. C., Carpenter, D. M., Fang, G., Weaver, M. A., Lin, F., Davis, S. M., Shea, C. M., Carter-Edwards, L., Dennis, A. M., Fisher, J. A., Golightly, Y. M., Hingtgen, S. D., Smith, A. M., Tan, J. T., Asher, G. N., Barritt, A. S., Blouin, R., Buchbinder, M., Hurt, C., Juengst, E. T., Mendoza, L. C., Reeve, B., Roman Isler, M. D., Wood, W. A., Ahalt, S., Agans, R. P., Dave, G. J., Lightfoot, A. F., Zhou, H., Skinner, A. C., Wilhelmsen, K. C., Song, L., Fischer, W. A., Peery, A. F., Powers, K. A., Ryan, A. E., Otey, C. A., Donaldson, S. H., Leeman, J., Kashuba, A. D., Gomez, S. M., Chung, A. E., Meyer, A. M., Parrott, M. C., Toles, M. P., Schmitt, C., Nichols, H. B. & Moran, T. P.

NIH National Center for Advancing Translational Sciences (NCATS)

9/26/134/30/18

Project: Research project

Annual Reports
Patient Care
Costs and Cost Analysis
Research

Research Output 1984 2017

8 Citations

Application of a mechanistic model to evaluate putative mechanisms of tolvaptan drug-induced liver injury and identify patient susceptibility factors

Woodhead, J. L., Brock, W. J., Roth, S. E., Shoaf, S. E., Brouwer, K. L. R., Church, R., Grammatopoulos, T. N., Stiles, L., Siler, S. Q., Howell, B. A., Mosedale, M., Watkins, P. B. & Shoda, L. K. M. Jan 1 2017 In : Toxicological Sciences. 155, 1, p. 61-74 14 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Liver
Autosomal Dominant Polycystic Kidney
Pharmaceutical Preparations
Wounds and Injuries
6 Citations

Candidate risk factors and mechanisms for tolvaptan-induced liver injury are identified using a collaborative cross approach

Mosedale, M., Kim, Y., Brock, W. J., Roth, S. E., Wiltshire, T., Eaddy, J. S., Keele, G. R., Corty, R. W., Xie, Y., Valdar, W. & Watkins, P. B. Apr 1 2017 In : Toxicological Sciences. 156, 2, p. 438-454 17 p., kfw269

Research output: Contribution to journalArticle

Liver
Chemical and Drug Induced Liver Injury
Wounds and Injuries
Secretory Leukocyte Peptidase Inhibitor
Autosomal Dominant Polycystic Kidney
7 Citations

Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury

Mikus, M. , Drobin, K. , Gry, M. , Bachmann, J. , Lindberg, J. , Yimer, G. , Aklillu, E. , Makonnen, E. , Aderaye, G. , Roach, J. , Fier, I. , Kampf, C. , Göpfert, J. , Perazzo, H. , Poynard, T. , Stephens, C. , Andrade, R. J. , Lucena, M. I. , Arber, N. , Uhlén, M. & 4 others Watkins, P. B., Schwenk, J. M., Nilsson, P. & Schuppe-Koistinen, I. Jan 1 2017 In : Liver International. 37, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Fatty Acid-Binding Proteins
Cadherins
Biomarkers
Alanine Transaminase
7 Citations

The role of quantitative systems pharmacology modeling in the prediction and explanation of idiosyncratic drug-induced liver injury

Woodhead, J. L., Watkins, P. B., Howell, B. A., Siler, S. Q. & Shoda, L. K. M. Feb 1 2017 In : Drug Metabolism and Pharmacokinetics. 32, 1, p. 40-45 6 p.

Research output: Contribution to journalReview article

Chemical and Drug Induced Liver Injury
Pharmacology
troglitazone
Biological Phenomena
Adaptive Immunity
15 Citations

Beyond miR-122: Identification of microRNA alterations in blood during a time course of hepatobiliary injury and biliary hyperplasia in rats

Church, R. J., Otieno, M., McDuffie, J. E., Singh, B., Sonee, M., Hall, L. R., Watkins, P. B., Ellinger-Ziegelbauer, H. & Harrill, A. H. Mar 1 2016 In : Toxicological Sciences. 150, 1, p. 3-14 12 p., kfv260

Research output: Contribution to journalArticle

MicroRNAs
Hyperplasia
Rats
Blood
Wounds and Injuries