• 47098 Citations
  • 91 h-Index
1948 …2018
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  • 2 Similar Profiles
Genes Medicine & Life Sciences
Gene Targeting Medicine & Life Sciences
Blood Pressure Medicine & Life Sciences
Kidney Medicine & Life Sciences
DNA Medicine & Life Sciences
Homologous Recombination Medicine & Life Sciences
Globins Medicine & Life Sciences
beta-Globins Medicine & Life Sciences

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Projects 1988 2017

Glomerular Basement Membrane
Albuminuria
Organized Financing
Diabetic Nephropathies
Confocal Microscopy
Glomerular Basement Membrane
Albumins
Kidney
Albuminuria
Gels
Bradykinin
Diabetes Complications
Mitochondrial DNA
DNA Damage
Nitric Oxide
Bradykinin
Diabetes Complications
Mitochondrial DNA
DNA Damage
Nitric Oxide
Bradykinin
Diabetes Complications
Mitochondrial DNA
DNA Damage
Nitric Oxide

Research Output 1948 2018

Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system

Govindapillai, A., Hotchkiss, A., Baguma-Nibasheka, M., Rose, R. A., Miquerol, L., Smithies, O., Maeda, N. & Pasumarthi, K. B. S. Dec 1 2018 In : Scientific Reports. 8, 1, 6939

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Embryonic Development
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Gene Expression
Cyclic GMP-Dependent Protein Kinases

GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure

Bai, X., Mangum, K., Kakoki, M., Smithies, O., Mack, C. P. & Taylor, J. M. Jan 2 2018 (Accepted/In press) In : Small GTPases. p. 1-10 10 p.

Research output: Contribution to journalArticle

Telephone lines
Blood Volume
Smooth Muscle Myocytes
Smooth Muscle
Blood Pressure

A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size

Willett, J. D. S., Lawrence, M. G., Wilder, J. C. & Smithies, O. Mar 31 2017 In : International journal of nanomedicine. 12, p. 2581-2592 12 p.

Research output: Contribution to journalArticle

Glycols
Gold
Nanoparticles
Adsorption
Pulp
8 Citations

Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules

Lawrence, M. G., Altenburg, M. K., Sanford, R., Willett, J. D., Bleasdale, B., Ballou, B., Wilder, J., Li, F., Miner, J. H., Berg, U. B. & Smithies, O. Mar 14 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 11, p. 2958-2963 6 p.

Research output: Contribution to journalArticle

Glomerular Basement Membrane
Nanoparticles
Kidney
Gold
Glycocalyx
40 Citations

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

Williams, P. A., Harder, J. M., Foxworth, N. E., Cochran, K. E., Philip, V. M., Porciatti, V., Smithies, O. & John, S. W. M. Feb 17 2017 In : Science. 355, 6326, p. 756-760 5 p.

Research output: Contribution to journalArticle

Niacinamide
Glaucoma
NAD
Therapeutic Uses
Neurodegenerative Diseases