• 17407 Citations
  • 61 h-Index
1981 …2020
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  • 11 Similar Profiles
Neoplasms Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Cell Aging Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Mutation Medicine & Life Sciences
Aging of materials Chemical Compounds
Tumors Chemical Compounds
Hematopoietic Stem Cells Medicine & Life Sciences

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Projects 1981 2020

Medical Students
Research
Mentors
Students
Posters
p16 Genes
Breast Neoplasms
Gene Expression
Drug Therapy
Walking
Credentialing
Immune System
Research
Therapeutics
Clinical Trials
Cell Aging
Osteoarthritis
Chondrocytes
Joints
Cartilage

Research Output 1992 2018

3 Citations

Enhancing Next-Generation Sequencing-Guided Cancer Care Through Cognitive Computing

Patel, N. M., Michelini, V. V., Snell, J. M., Balu, S., Hoyle, A. P., Parker, J., Hayward, M. C., Eberhard, D. A., Salazar, A. H., McNeillie, P., Xu, J., Huettner, C. S., Koyama, T., Utro, F., Rhrissorrakrai, K., Norel, R., Bilal, E., Royyuru, A., Parida, L., Earp, H. S. & 5 othersGrilley-Olson, J. E., Hayes, D. N., Harvey, S. J., Sharpless, N. E. & Kim, W. Y., Feb 1 2018, In : Oncologist. 23, 2, p. 179-185 7 p.

Research output: Contribution to journalArticle

Genomics
Clinical Trials
Neoplasms
Patient Care
Precision Medicine
5 Citations

Exploiting drug addiction mechanisms to select against mapki-resistant melanoma

Hong, A., Moriceau, G., Sun, L., Lomeli, S., Piva, M., Damoiseaux, R., Holmen, S. L., Sharpless, N. E., Hugo, W. & Lo, R. S., Jan 1 2018, In : Cancer Discovery. 8, 1, p. 74-93 20 p.

Research output: Contribution to journalArticle

Substance-Related Disorders
Melanoma
Cell Death
DNA Damage
Pharmaceutical Preparations
3 Citations

Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Diekman, B. O., Sessions, G. A., Collins, J. A., Knecht, A. K., Strum, S. L., Mitin, N. K., Carlson, C. S., Loeser, R. F. & Sharpless, N. E., Jan 1 2018, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Chondrocytes
Osteoarthritis
Biomarkers
Phenotype
Cartilage
3 Citations

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, H. E., Angus, S. P., Bo, T., Roques, J., Tagliatela, A. C., Darr, D. B., Karagoz, K., Sciaky, N., Gatza, M. L., Sharpless, N. E., Johnson, G. L. & Bear, J. E., Jan 15 2018, In : Cancer Research. 78, 2, p. 542-557 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasms
Pharmaceutical Preparations
Therapeutics
4 Citations

Docetaxel-loaded PLGA nanoparticles improve efficacy in taxane-resistant triple-negative breast cancer

Bowerman, C. J., Byrne, J. D., Chu, K. S., Schorzman, A. N., Keeler, A. W., Sherwood, C. A., Perry, J. L., Luft, J. C., Darr, D. B., Deal, A. M., Napier, M. E., Zamboni, W. C., Sharpless, N. E., Perou, C. M. & DeSimone, J. M., Jan 1 2017, In : Nano Letters. 17, 1, p. 242-248 7 p.

Research output: Contribution to journalArticle

docetaxel
breast
cancer
Nanoparticles
nanoparticles