• 16924 Citations
  • 60 h-Index
1981 …2020
If you made any changes in Pure these will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 20 Similar Profiles
Neoplasms Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Cell Aging Medicine & Life Sciences
Stem Cells Medicine & Life Sciences
Telomere Medicine & Life Sciences
Mutation Medicine & Life Sciences
Tumors Chemical Compounds
Carcinogenesis Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1981 2020

Medical Students
Research
Mentors
Students
Posters
p16 Genes
Breast Neoplasms
Gene Expression
Drug Therapy
Walking
Credentialing
Immune System
Research
Therapeutics
Clinical Trials
Cell Aging
Osteoarthritis
Chondrocytes
Joints
Cartilage

Research Output 1992 2018

3 Citations

Enhancing Next-Generation Sequencing-Guided Cancer Care Through Cognitive Computing

Patel, N. M. , Michelini, V. V. , Snell, J. M. , Balu, S. , Hoyle, A. P. , Parker, J. S. , Hayward, M. C. , Eberhard, D. A. , Salazar, A. H. , McNeillie, P. , Xu, J. , Huettner, C. S. , Koyama, T. , Utro, F. , Rhrissorrakrai, K. , Norel, R. , Bilal, E. , Royyuru, A. , Parida, L. , Earp, H. S. & 5 others Grilley-Olson, J. E., Hayes, D. N., Harvey, S. J., Sharpless, N. E. & Kim, W. Y., Feb 1 2018, In : Oncologist. 23, 2, p. 179-185 7 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Precision Medicine
Artificial Intelligence
Genomics
Clinical Trials
4 Citations

Exploiting drug addiction mechanisms to select against mapki-resistant melanoma

Hong, A., Moriceau, G., Sun, L., Lomeli, S., Piva, M., Damoiseaux, R., Holmen, S. L., Sharpless, N. E., Hugo, W. & Lo, R. S. Jan 1 2018 In : Cancer Discovery. 8, 1, p. 74-93 20 p.

Research output: Contribution to journalArticle

Substance-Related Disorders
Melanoma
Cell Death
DNA Damage
Pharmaceutical Preparations
2 Citations

Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Diekman, B. O., Sessions, G. A., Collins, J. A., Knecht, A. K., Strum, S. L., Mitin, N. K., Carlson, C. S., Loeser, R. F. & Sharpless, N. E., Jan 1 2018, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Chondrocytes
Osteoarthritis
Biomarkers
Phenotype
Cell Aging
2 Citations

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, H. E., Angus, S. P., Bo, T., Roques, J., Tagliatela, A. C., Darr, D. B., Karagoz, K., Sciaky, N., Gatza, M. L., Sharpless, N. E., Johnson, G. L. & Bear, J. E., Jan 15 2018, In : Cancer Research. 78, 2, p. 542-557 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasms
Pharmaceutical Preparations
Therapeutics
1 Citations

Docetaxel-loaded PLGA nanoparticles improve efficacy in taxane-resistant triple-negative breast cancer

Bowerman, C. J., Byrne, J. D., Chu, K. S., Schorzman, A. N., Keeler, A. W., Sherwood, C. A., Perry, J. L., Luft, J. C., Darr, D. B., Deal, A. M., Napier, M. E., Zamboni, W. C., Sharpless, N. E., Perou, C. M. & DeSimone, J. M., Jan 1 2017, In : Nano Letters. 17, 1, p. 242-248 7 p.

Research output: Contribution to journalArticle

docetaxel
breast
cancer
Nanoparticles
nanoparticles