• 9293 Citations
  • 54 h-Index
1976 …2018
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  • 11 Similar Profiles
Molecular Dynamics Simulation Medicine & Life Sciences
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Protein Folding Medicine & Life Sciences
Mutation Medicine & Life Sciences
RNA Medicine & Life Sciences
Thermodynamics Medicine & Life Sciences
Molecular dynamics Chemical Compounds
Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences

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Projects 1976 2017

Research Output 1994 2018

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to ytosolic and luminal Ca2+

Xu, L., Mowrey, D. D., Chirasani, V. R., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 6, p. 2015-2028 14 p.

Research output: Contribution to journalArticle

S 6
Ryanodine Receptor Calcium Release Channel
Linings
Muscle
Skeletal Muscle
3 Citations

High-speed atomic force microscopy reveals structural dynamics of α -synuclein monomers and dimers

Zhang, Y., Hashemi, M., Lv, Z., Williams, B., Popov, K. I., Dokholyan, N. V. & Lyubchenko, Y. L., Mar 28 2018, In : Journal of Chemical Physics. 148, 12, 123322

Research output: Contribution to journalArticle

Neurodegenerative diseases
dynamic structural analysis
Structural dynamics
Dimers
Self assembly
1 Citations
Amyotrophic Lateral Sclerosis
Cell Survival
Motor Neurons
Poisons
Neurodegenerative Diseases

Mapping allosteric linkage to channel gating by extracellular domains in the human epithelial sodium channel

Shobair, M., Popov, K. I., Dang, Y. L., He, H., Jackson Stutts, M. & Dokholyan, N. V. Jan 1 2018 In : Journal of Biological Chemistry. 293, 10, p. 3675-3684 10 p.

Research output: Contribution to journalArticle

Electrophysiology
Epithelial Sodium Channels
Chromosome Mapping
Degenerin Sodium Channels
Cysteine
2 Citations

Structural complexity and functional diversity of plant NADPH oxidases

Kaur, G., Guruprasad, K., Temple, B. R. S., Shirvanyants, D. G., Dokholyan, N. V. & Pati, P. K., Jan 1 2018, In : Amino Acids. 50, 1, p. 79-94 16 p.

Research output: Contribution to journalArticle