• 2513 Citations
  • 19 h-Index
19972019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Mitochondria Chemical Compounds
Permeability Medicine & Life Sciences
Liver Chemical Compounds
Liver Mitochondrion Medicine & Life Sciences
Adenosine Triphosphate Chemical Compounds
Cystic Fibrosis Medicine & Life Sciences
Membranes Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1997 2019

Research Output 2001 2018

  • 2513 Citations
  • 19 h-Index
  • 23 Article
  • 3 Review article
  • 1 Comment/debate

Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel

Fay, J. F., Aleksandrov, L. A., Jensen, T. J., Cui, L. L., Kousouros, J. N., He, L., Aleksandrov, A. A., Gingerich, D. S., Riordan, J. R. & Chen, J. Z., Oct 30 2018, In : Biochemistry. 57, 43, p. 6234-6246 13 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Phosphorylation
Adenosinetriphosphate
Medical imaging
Diagnostic Imaging
5 Citations

Transmembrane helical interactions in the CFTR channel pore

Das, J., Aleksandrov, A. A., Cui, L., He, L., Riordan, J. R. & Dokholyan, N. V., Jun 1 2017, In : PLoS Computational Biology. 13, 6, e1005594.

Research output: Contribution to journalArticle

Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
cystic fibrosis
Conductance
Regulator
17 Citations
Cystic Fibrosis Transmembrane Conductance Regulator
Proteins
Ion Channels
Nucleotides
24 Citations

Restoration of NBD1 thermal stability is necessary and sufficient to correct Δf508 CFTR folding and assembly

He, L., Aleksandrov, A. A., An, J., Cui, L., Yang, Z., Brouillette, C. G. & Riordan, J. R., Jan 16 2015, In : Journal of Molecular Biology. 427, 1, p. 106-120 15 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Hot Temperature
Mutation
Ion Channels
Cystic Fibrosis
9 Citations

Thermal stability of purified and reconstituted CFTR in a locked open channel conformation

Aleksandrov, L. A., Jensen, T. J., Cui, L., Kousouros, J. N., He, L., Aleksandrov, A. A. & Riordan, J. R., Aug 28 2015, In : Protein Expression and Purification. 116, p. 159-166 8 p.

Research output: Contribution to journalArticle

Hot Temperature
Mutation
Proteins
ATP-Binding Cassette Transporters
Membrane Glycoproteins