• 6484 Citations
  • 44 h-Index
1981 …2018
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  • 3 Similar Profiles
Phosphorylation Chemical Compounds
Phosphotransferases Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Cells Chemical Compounds

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Projects 1981 2018

Research Output 1988 2018

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

Krulikas, L. J., McDonald, I. M., Lee, B., Okumu, D. O., East, M. P., Gilbert, T. S. K., Herring, L. E., Golitz, B. T., Wells, C. I., Axtman, A. D., Zuercher, W. J., Willson, T. M., Kireev, D., Yeh, J. J., Johnson, G. L., Baines, A. T. & Graves, L. M., Sep 1 2018, In : SLAS Discovery. 23, 8, p. 850-861 12 p.

Research output: Contribution to journalArticle

gemcitabine
Preclinical Drug Evaluations
Cell growth
Pancreatic Neoplasms
Screening
6 Citations

Chronic e-cigarette exposure alters the human bronchial epithelial proteome

Ghosh, A., Coakley, R. D., Mascenik, T., Rowell, T. R., Davis, E. S., Rogers, K., Webster, M. J., Dang, H., Herring, L. E., Sassano, M. F., Livraghi-Butrico, A., Van Buren, S. K., Graves, L. M., Herman, M. A., Randell, S. H., Alexis, N. E. & Tarran, R., Jul 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Propylene Glycol
Proteome
Tobacco Products
Vegetables
Glycerol
2 Citations

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

Asquith, C. R. M., Laitinen, T., Bennett, J. M., Godoi, P. H., East, M. P., Tizzard, G. J., Graves, L. M., Johnson, G. L., Dornsife, R. E., Wells, C. I., Elkins, J. M., Willson, T. M. & Zuercher, W. J., Jan 8 2018, In : ChemMedChem. 13, 1, p. 48-66 19 p.

Research output: Contribution to journalArticle

Cyclin G
Phosphotransferases
Anti-Bacterial Agents
Amines

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

Vaseva, A. V., Blake, D. R., Gilbert, T. S. K., Ng, S., Hostetter, G., Azam, S. H., Ozkan-Dagliyan, I., Gautam, P., Bryant, K. L., Pearce, K. H., Herring, L. E., Han, H., Graves, L. M., Witkiewicz, A. K., Knudsen, E. S., Pecot, C. V., Rashid, N., Houghton, P. J., Wennerberg, K., Cox, A. D. & 1 othersDer, C. J., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Adenocarcinoma
Ubiquitin-Protein Ligases
Protein Stability
Proteasome Endopeptidase Complex
Growth

p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression

Liu, Y., Leslie, P. L., Jin, A., Itahana, K., Graves, L. M. & Zhang, Y., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3892-3902 11 p.

Research output: Contribution to journalArticle

Glucosidases
Endoplasmic Reticulum Stress
Endoplasmic Reticulum
Homeostasis
Fatty Acids