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  • 7 Similar Profiles
Phosphorylation Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Chemical activation Chemical Compounds
Proteins Medicine & Life Sciences
Cells Chemical Compounds
Epithelial Cells Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences

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Projects 1981 2018

Research Output 1988 2017

9 Citations

Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex

Zawistowski, J. S. , Bevill, S. M. , Goulet, D. R. , Stuhlmiller, T. J. , Beltran, A. S. , Olivares-Quintero, J. F. , Singh, D. , Sciaky, N. , Parker, J. S. , Rashid, N. U. , Chen, X. , Duncan, J. S. , Whittle, M. C. , Angus, S. P. , Velarde, S. H. , Golitz, B. T. , He, X. , Santos, C. , Darr, D. B. , Gallagher, K. & 5 others Graves, L. M., Perou, C. M., Carey, L. A., Shelton Earp, H. & Johnson, G. L. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 302-321 20 p.

Research output: Research - peer-reviewArticle

Positive Transcriptional Elongation Factor B
Mitogen-Activated Protein Kinase Kinases
Neoplasms
Triple Negative Breast Neoplasms
trametinib
1 Citations

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

Stratford, J. K., Yan, F., Hill, R. A., Major, M. B., Graves, L. M., Der, C. J. & Yeh, J. J. Apr 1 2017 In : PLoS ONE. 12, 4, e0174863

Research output: Research - peer-reviewArticle

Chromosomal Instability
Ubiquitin
Pancreatic Neoplasms
Adenocarcinoma
Pharmacology
4 Citations

Kinome profiling identifies druggable targets for novel human cytomegalovirus (HCMV) antivirals

Arend, K. C., Lenarcic, E. M., Vincent, H. A., Rashid, N., Lazear, E., McDonald, I. M., Gilbert, T. S. K., East, M. P., Herring, L. E., Johnson, G. L., Graves, L. M. & Moorman, N. J. Apr 1 2017 In : Molecular and Cellular Proteomics. 16, 4, p. S263-S276

Research output: Research - peer-reviewArticle

Cytomegalovirus
Antiviral Agents
Phosphotransferases
Mass Spectrometry
Viruses
2 Citations

Probing the global kinome and phosphoproteome in Chlamydomonas reinhardtii via sequential enrichment and quantitative proteomics

Werth, E. G., McConnell, E. W., Gilbert, T. S. K., Couso Lianez, I., Perez, C. A., Manley, C. K., Graves, L. M., Umen, J. G. & Hicks, L. M. Jan 1 2017 In : Plant Journal. 89, 2, p. 416-426 11 p.

Research output: Research - peer-reviewArticle

Chlamydomonas reinhardtii
proteomics
phosphotransferases (kinases)
Proteomics
Phosphorylation
20 Citations

CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation

Liu, Y., Clegg, H. V., Leslie, P. L., Di, J., Tollini, L. A., He, Y., Kim, T. H., Jin, A., Graves, L. M., Zheng, J. & Zhang, Y. Jun 1 2015 In : Cell Death and Differentiation. 22, 6, p. 1035-1046 12 p.

Research output: Research - peer-reviewArticle

Mitochondrial Membranes
Apoptosis
Mitochondria
Proteins
Mitochondrial Proteins