• 6484 Citations
  • 44 h-Index
1981 …2018
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  • 3 Similar Profiles
Phosphorylation Chemical Compounds
Phosphotransferases Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Cells Chemical Compounds

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Projects 1981 2018

Research Output 1988 2018

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

Krulikas, L. J., McDonald, I. M., Lee, B., Okumu, D. O., East, M. P., Gilbert, T. S. K., Herring, L. E., Golitz, B. T., Wells, C. I., Axtman, A. D., Zuercher, W. J., Willson, T. M., Kireev, D., Yeh, J. J., Johnson, G. L., Baines, A. T. & Graves, L. M., Sep 1 2018, In : SLAS Discovery. 23, 8, p. 850-861 12 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
Cell growth
Pancreatic Neoplasms
6 Citations

Chronic e-cigarette exposure alters the human bronchial epithelial proteome

Ghosh, A., Coakley, R. D., Mascenik, T., Rowell, T. R., Davis, E. S., Rogers, K., Webster, M. J., Dang, H., Herring, L. E., Sassano, M. F., Livraghi-Butrico, A., Van Buren, S. K., Graves, L. M., Herman, M. A., Randell, S. H., Alexis, N. E. & Tarran, R., Jul 1 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Propylene Glycol
Tobacco Products
2 Citations

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

Asquith, C. R. M., Laitinen, T., Bennett, J. M., Godoi, P. H., East, M. P., Tizzard, G. J., Graves, L. M., Johnson, G. L., Dornsife, R. E., Wells, C. I., Elkins, J. M., Willson, T. M. & Zuercher, W. J., Jan 8 2018, In : ChemMedChem. 13, 1, p. 48-66 19 p.

Research output: Contribution to journalArticle

Cyclin G
Anti-Bacterial Agents

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

Vaseva, A. V., Blake, D. R., Gilbert, T. S. K., Ng, S., Hostetter, G., Azam, S. H., Ozkan-Dagliyan, I., Gautam, P., Bryant, K. L., Pearce, K. H., Herring, L. E., Han, H., Graves, L. M., Witkiewicz, A. K., Knudsen, E. S., Pecot, C. V., Rashid, N., Houghton, P. J., Wennerberg, K., Cox, A. D. & 1 othersDer, C. J., Jan 1 2018, (Accepted/In press) In : Cancer Cell.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Protein Stability
Proteasome Endopeptidase Complex

p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression

Liu, Y., Leslie, P. L., Jin, A., Itahana, K., Graves, L. M. & Zhang, Y., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3892-3902 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Endoplasmic Reticulum
Fatty Acids