Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 3 Similar Profiles
Phosphorylation Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Chemical activation Chemical Compounds
Epidermal Growth Factor Receptor Medicine & Life Sciences
Cells Chemical Compounds
Epithelial Cells Medicine & Life Sciences

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Projects 1981 2018

Research Output 1988 2018

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

Asquith, C. R. M., Laitinen, T., Bennett, J. M., Godoi, P. H., East, M. P., Tizzard, G. J., Graves, L. M., Johnson, G. L., Dornsife, R. E., Wells, C. I., Elkins, J. M., Willson, T. M. & Zuercher, W. J. Jan 8 2018 In : ChemMedChem. 13, 1, p. 48-66 19 p.

Research output: Contribution to journalArticle

Cyclin G
Phosphotransferases
Anti-Bacterial Agents
Amines
Communicable Diseases
1 Citations

Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

Collins, K. A. L., Stuhlmiller, T. J., Zawistowski, J. S., East, M. P., Pham, T. T., Hall, C. R., Goulet, D. R., Bevill, S. M., Angus, S. P., Velarde, S. H., Sciaky, N., Oprea, T. I., Graves, L. M., Johnson, G. L. & Gomez, S. M. Jan 1 2018 In : Oncotarget. 9, 21, p. 15480-15497 18 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Breast Neoplasms
Tumor Cell Line
Sepharose
2 Citations

BIRC6 mediates imatinib resistance independently of Mcl-1

Okumu, D. O., East, M. P., Levine, M., Herring, L. E., Zhang, R., Gilbert, T. S. K., Litchfield, D. W., Zhang, Y. & Graves, L. M. May 1 2017 In : PloS one. 12, 5, e0177871

Research output: Contribution to journalArticle

Myeloid Cell Leukemia Sequence 1 Protein
Neoplasm Drug Resistance
Cyclin-Dependent Kinase 9
Inhibitor of Apoptosis Proteins
src-Family Kinases
3 Citations

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma: Neuro Oncol

McNeill, R. S. , Canoutas, D. A. , Stuhlmiller, T. J. , Dhruv, H. D. , Irvin, D. M. , Bash, R. E. , Angus, S. P. , Herring, L. E. , Simon, J. M. , Skinner, K. R. , Limas, J. C. , Chen, X. , Schmid, R. S. , Siegel, M. B. , Van Swearingen, A. E. D. , Hadler, M. J. , Sulman, E. P. , Sarkaria, J. N. , Anders, C. K. , Graves, L. M. & 3 others Berens, M. E., Johnson, G. L. & Miller, C. R. Apr 6 2017 In : Neuro-Oncology. 19, 11, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Glioblastoma
Protein Kinase Inhibitors
Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase Kinases
18 Citations

Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex

Zawistowski, J. S. , Bevill, S. M. , Goulet, D. R. , Stuhlmiller, T. J. , Beltran, A. S. , Olivares-Quintero, J. F. , Singh, D. , Sciaky, N. , Parker, J. S. , Rashid, N. U. , Chen, X. , Duncan, J. S. , Whittle, M. C. , Angus, S. P. , Velarde, S. H. , Golitz, B. T. , He, X. , Santos, C. , Darr, D. B. , Gallagher, K. & 5 others Graves, L. M., Perou, C. M., Carey, L. A., Shelton Earp, H. & Johnson, G. L. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 302-321 20 p.

Research output: Contribution to journalArticle

Positive Transcriptional Elongation Factor B
Mitogen-Activated Protein Kinase Kinases
Triple Negative Breast Neoplasms
Receptor Protein-Tyrosine Kinases
Neoplasms