Research Output 1974 2017

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Review article
2016
8 Citations

Current and future theranostic applications of the lipid-calcium-phosphate nanoparticle platform

Satterlee, A. B. & Huang, L. 2016 In : Theranostics. 6, 7, p. 918-929 12 p.

Research output: Research - peer-reviewReview article

Nanoparticles
Lipids
Theranostic Nanomedicine
calcium phosphate
Cytotoxins
2015
36 Citations

Delivery of oligonucleotides with lipid nanoparticles

Wang, Y., Miao, L., Satterlee, A. & Huang, L. Jan 1 2015 In : Advanced Drug Delivery Reviews. 87, p. 68-80 13 p.

Research output: Research - peer-reviewReview article

Oligonucleotides
Nanoparticles
Lipids
Therapeutics
Drug Delivery Systems
104 Citations

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

Chen, Y., Gao, D. Y. & Huang, L. Jan 1 2015 In : Advanced Drug Delivery Reviews. 81, p. 128-141 14 p.

Research output: Research - peer-reviewReview article

MicroRNAs
Neoplasms
Therapeutics
Gene Expression
Small Untranslated RNA
2014
7 Citations

Hepatic RNA interference: Delivery by synthetic vectors

Haynes, M. T. & Huang, L. Feb 2014 In : Drug Delivery and Translational Research. 4, 1, p. 61-73 13 p.

Research output: Research - peer-reviewReview article

RNA Interference
Liver
Therapeutics
RNA
Technology
45 Citations

Nanoparticles containing insoluble drug for cancer therapy

Guo, S. & Huang, L. Jan 1 2014 In : Biotechnology Advances. 32, 4, p. 778-788 11 p.

Research output: Research - peer-reviewReview article

Nanoparticles
Drug Therapy
Neoplasms
Pharmaceutical Preparations
Drug Compounding
32 Citations

Non-viral nanocarriers for siRNA delivery in breast cancer

Zhang, J., Li, X. & Huang, L. Sep 28 2014 In : Journal of Controlled Release. 190, p. 440-450 11 p.

Research output: Research - peer-reviewReview article

Small Interfering RNA
Breast Neoplasms
Gene Silencing
Carcinogenesis
Therapeutics
2013
7 Citations

Strategies on the nuclear-targeted delivery of genes

Yao, J., Fan, Y., Li, Y. & Huang, L. Dec 1 2013 In : Journal of Drug Targeting. 21, 10, p. 926-939 14 p.

Research output: Research - peer-reviewReview article

Nuclear Envelope
Genes
Cell Nucleus Active Transport
Transgenes
Genome
2012
112 Citations

Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

Watson, D. S., Endsley, A. N. & Huang, L. Mar 16 2012 In : Vaccine. 30, 13, p. 2256-2272 17 p.

Research output: Research - peer-reviewReview article

cell-mediated immunity
vaccines
antigens
antibodies
Liposomes
24 Citations

Intelligent design of multifunctional lipid-coated nanoparticle platforms for cancer therapy

Ramishetti, S. & Huang, L. Dec 2012 In : Therapeutic Delivery. 3, 12, p. 1429-1445 17 p.

Research output: Research - peer-reviewReview article

Religious Philosophies
Nanoparticles
Lipids
Neoplasms
Therapeutics
33 Citations

Lipid-based vectors for siRNA delivery

Zhang, S., Zhi, D. & Huang, L. Nov 1 2012 In : Journal of Drug Targeting. 20, 9, p. 724-735 12 p.

Research output: Research - peer-reviewReview article

Small Interfering RNA
Lipids
Particle Size
Liposomes
Organelles
2011
31 Citations

Cancer immunotherapy and nanomedicine

Sheng, W. Y. & Huang, L. Feb 2011 In : Pharmaceutical Research. 28, 2, p. 200-214 15 p.

Research output: Research - peer-reviewReview article

Medical nanotechnology
Immune system
Nanomedicine
Immunotherapy
Neoplasms
72 Citations

Nanoparticles escaping RES and endosome: Challenges for siRNA delivery for cancer therapy

Huang, L. & Guo, S. 2011 In : Journal of Nanomaterials. 2011, 742895

Research output: Research - peer-reviewReview article

Small Interfering RNA
Nanoparticles
Tumors
Polyethylene glycols
Brushes
66 Citations

The suppressive tumor microenvironment: A challenge in cancer immunotherapy

Vasievich, E. A. & Huang, L. Jun 6 2011 In : Molecular Pharmaceutics. 8, 3, p. 635-641 7 p.

Research output: Research - peer-reviewReview article

Tumor Microenvironment
Immunotherapy
Neoplasms
Therapeutics
Macrophages
2009
291 Citations

Lipid-based systemic delivery of siRNA

Tseng, Y. C., Mozumdar, S. & Huang, L. Jul 25 2009 In : Advanced Drug Delivery Reviews. 61, 9, p. 721-731 11 p.

Research output: Research - peer-reviewReview article

RNA Interference
Small Interfering RNA
Lipids
RNAi Therapeutics
Architectural Accessibility
172 Citations

Nonviral methods for siRNA delivery

Gao, K. & Huang, L. Jun 1 2009 In : Molecular Pharmaceutics. 6, 3, p. 651-658 8 p.

Research output: Research - peer-reviewReview article

Small Interfering RNA
Therapeutics
Messenger RNA
Validation Studies
Genomics
31 Citations

Self-assembled lipid nanomedicines for siRNA tumor targeting

Tseng, Y. C. & Huang, L. Aug 2009 In : Journal of Biomedical Nanotechnology. 5, 4, p. 351-363 13 p.

Research output: Research - peer-reviewReview article

Nanomedicine
Small Interfering RNA
Lipids
Neoplasms
Medical nanotechnology
2008
33 Citations

Targeted delivery of siRNA by nonviral vectors: Lessons learned from recent advances

Li, S. D. & Huang, L. Dec 2008 In : Current Opinion in Investigational Drugs. 9, 12, p. 1317-1323 7 p.

Research output: Research - peer-reviewReview article

Small Interfering RNA
Therapeutics
Inborn Genetic Diseases
RNA Interference
Oligonucleotides
43 Citations

Tumor-targeted delivery of siRNA by non-viral vector: Safe and effective cancer therapy

Chen, Y. & Huang, L. Dec 1 2008 In : Expert Opinion on Drug Delivery. 5, 12, p. 1301-1311 11 p.

Research output: Research - peer-reviewReview article

Small Interfering RNA
Neoplasms
Therapeutics
Therapeutic Uses
RNA Interference
2006
282 Citations

Gene therapy progress and prospects: Non-viral gene therapy by systemic delivery

Li, S. D. & Huang, L. Sep 1 2006 In : Gene Therapy. 13, 18, p. 1313-1319 7 p.

Research output: Research - peer-reviewReview article

Genetic Therapy
Genes
Oligonucleotides
Plasmids
Research Personnel
22 Citations

Local Drug Delivery to Bladder Using Technology Innovations

Tyagi, P., Tyagi, S., Kaufman, J., Huang, L. & de Miguel, F. Nov 1 2006 In : Urologic Clinics of North America. 33, 4, p. 519-530 12 p.

Research output: Research - peer-reviewReview article

Urinary Bladder
Technology
Pharmaceutical Preparations
Therapeutics
Liposomes
62 Citations

Recent advances in intravesical drug/gene delivery

Tyagi, P., Wu, P. C., Chancellor, M., Yoshimura, N. & Huang, L. Jul 2006 In : Molecular Pharmaceutics. 3, 4, p. 369-379 11 p.

Research output: Research - peer-reviewReview article

Pharmaceutical Preparations
Genes
Urinary Bladder
Therapeutics
Drug Administration Routes
2005
130 Citations

Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity

Zhang, J. S., Liu, F. & Huang, L. Apr 5 2005 In : Advanced Drug Delivery Reviews. 57, 5, p. 689-698 10 p.

Research output: Research - peer-reviewReview article

Liposomes
Pharmacokinetics
DNA
Injections
Kupffer Cells
22 Citations

Lipid-protamine-DNA-mediated antigen delivery

Vangasseri, D. P., Han, S. J. & Huang, L. Oct 2005 In : Current Drug Delivery. 2, 4, p. 401-406 6 p.

Research output: Research - peer-reviewReview article

Protamines
Vaccines
Lipids
Antigens
Peptides
37 Citations

Non-Viral Vector as Vaccine Carrier

Chen, W. C. & Huang, L. Dec 1 2005 In : Advances in Genetics. 54, p. 315-337 23 p.

Research output: Research - peer-reviewReview article

Vaccines
Liposomes
Antigens
DNA Vaccines
Human Development
20 Citations

Recent advances in non-viral gene delivery.

Conwell, C. C. & Huang, L. Dec 1 2005 In : Advances in genetics.. 53, p. 3-18 16 p.

Research output: Research - peer-reviewReview article

Genes
Gene Transfer Techniques
Genetic Therapy
Medicine
Gene Expression
2003
3 Citations

Targeted gene delivery: The role of peptide nucleic acid

Liang, K. W., Liu, F. & Huang, L. 2003 In : Letters in Peptide Science. 10, 3-4, p. 161-167 7 p.

Research output: Research - peer-reviewReview article

Peptide Nucleic Acids
Genes
Particle Size
polycations
Particle size
2002
28 Citations

Codelivery of NF-ΚB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transfer

Tan, Y., Zhang, J. S. & Huang, L. Dec 1 2002 In : Molecular Therapy. 6, 6, p. 804-812 9 p.

Research output: Research - peer-reviewReview article

Oligodeoxyribonucleotides
Liposomes
DNA
Genes
polycations
714 Citations

Gene therapy progress and prospects: Nonviral vectors

Niidome, T. & Huang, L. Jan 1 2002 In : Gene Therapy. 9, 24, p. 1647-1652 6 p.

Research output: Research - peer-reviewReview article

Genetic Therapy
DNA
Genes
Plasmids
Religious Philosophies
27 Citations

LPD nanoparticles--novel nonviral vector for efficient gene delivery.

Tan, Y., Whitmore, M., Li, S., Frederik, P. & Huang, L. 2002 In : Methods in molecular medicine. 69, p. 73-81 9 p.

Research output: Research - peer-reviewReview article

Gene Transfer Techniques
Genetic Vectors
Nanotechnology
Polyamines
Liposomes
2001
519 Citations

Nonviral vectors in the new millennium: Delivery barriers in gene transfer

Nishikawa, M. & Huang, L. 2001 In : Human Gene Therapy. 12, 8, p. 861-870 10 p.

Research output: Research - peer-reviewReview article

Genes
DNA
Inborn Genetic Diseases
Electroporation
Blood Circulation
16 Citations

Systemic administration of naked DNA: gene transfer to skeletal muscle.

Liu, F., Liang, K. W. & Huang, L. Aug 2001 In : Mol Interv. 1, 3, p. 168-172 5 p.

Research output: Research - peer-reviewReview article

Skeletal Muscle
Muscles
DNA
Genes
Gene transfer
2000
233 Citations

Structure and function of lipid-DNA complexes for gene delivery

Chesnoy, S. & Huang, L. 2000 In : Annual Review of Biophysics and Biomolecular Structure. 29, p. 27-47 21 p.

Research output: Research - peer-reviewReview article

Lipids
DNA
Genes
In Vitro Techniques
Transfection
1999
9 Citations

DNA condensed by polycations and lipids for gene transfer

Chesnoy, S. & Huang, L. Jan 1999 In : S.T.P. Pharma Sciences. 9, 1, p. 5-12 8 p.

Research output: Research - peer-reviewReview article

Liposomes
Lipids
DNA
Genes
polycations
1998
31 Citations

Liposome-based gene therapy

Tseng, W. C. & Huang, L. Aug 1 1998 In : Pharmaceutical Science and Technology Today. 1, 5, p. 206-213 8 p.

Research output: Research - peer-reviewReview article

Liposomes
Genetic Therapy
Transfection
Plasmids
Nuclear Localization Signals
1997
164 Citations

Lipidic vector systems for gene transfer

Lee, R. J. & Huang, L. 1997 In : Critical Reviews in Therapeutic Drug Carrier Systems. 14, 2, p. 173-206 34 p.

Research output: Research - peer-reviewReview article

Genes
DNA
Liposomes
Poisons
Genetic Therapy
1996
19 Citations

Lipidic supramolecular assemblies for gene transfer

Li, S. & Huang, L. Jan 1 1996 In : Journal of Liposome Research. 6, 3, p. 589-608 20 p.

Research output: Research - peer-reviewReview article

Genes
Polylysine
Liposomes
Intravenous Administration
Transfection
1995
616 Citations

Cationic liposome-mediated gene transfer

Gao, X. & Huang, L. 1995 In : Gene Therapy. 2, 10, p. 710-722 13 p.

Research output: Research - peer-reviewReview article

Liposomes
Genes
Genetic Therapy
Safety
DNA
47 Citations

Interaction of PEG-phospholipid conjugates with phospholipid: implications in liposomal drug delivery

Bedu-Addo, F. K. & Huang, L. Jan 1 1995 In : Advanced Drug Delivery Reviews. 16, 2-3, p. 235-247 13 p.

Research output: Research - peer-reviewReview article

Phospholipids
Pharmaceutical Preparations
Phosphatidylcholines
Cholesterol
Micelles
6 Citations

Targeted Immunoliposomes: Potential Role in the Delivery of Cytotoxic Drugs

Mori, A. & Huang, L. 1995 In : Clinical Immunotherapeutics. 3, 3, p. 227-240 14 p.

Research output: Research - peer-reviewReview article

Pharmaceutical Preparations
Liposomes
Oligonucleotides
Plasmids
Pharmacokinetics
7 Citations

The use of liposomes in the therapy of liver disease

Yao, T., Huang, L. & Zern, M. A. Dec 5 1995 In : Advanced Drug Delivery Reviews. 17, 3, p. 239-246 8 p.

Research output: Research - peer-reviewReview article

Liposomes
Physiology
Chemical modification
Biodegradation
Liver
1992
316 Citations

Phosphatodylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications

Litzinger, D. C. & Huang, L. Aug 14 1992 In : BBA - Reviews on Biomembranes. 1113, 2, p. 201-227 27 p.

Research output: Research - peer-reviewReview article

Phosphatidylethanolamines
Drug Carriers
Structural Models
Cytarabine
Lipid Bilayers