• 28352 Citations
  • 83 h-Index
1965 …2019
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Research Output 1965 2018

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Review article
2018
3 Citations

Biologically active quinoline and quinazoline alkaloids part I

Shang, X. F., Morris-Natschke, S. L., Liu, Y. Q., Guo, X., Xu, X. S., Goto, M., Li, J. C., Yang, G. Z. & Lee, K. H., May 1 2018, In : Medicinal Research Reviews. 38, 3, p. 775-828 54 p.

Research output: Contribution to journalReview article

1 Citations

Biologically active quinoline and quinazoline alkaloids part II

Shang, X. F., Morris-Natschke, S. L., Yang, G. Z., Liu, Y. Q., Guo, X., Xu, X. S., Goto, M., Li, J. C., Zhang, J. Y. & Lee, K. H., Sep 1 2018, In : Medicinal Research Reviews. 38, 5, p. 1614-1660 47 p.

Research output: Contribution to journalReview article

Quinazolines
Alkaloids
Antitussive Agents
Antiparasitic Agents
Biological Products

Chemical structures and biological activities of limonoids from the genus swietenia (meliaceae)

Sun, Y. P., Jin, W. F., Wang, Y. Y., Wang, G., Morris-Natschke, S. L., Liu, J. S., Wang, G. K. & Lee, K. H. Jan 1 2018 In : Molecules. 23, 7, 1588

Research output: Contribution to journalReview article

subtropical regions
Limonins
Meliaceae
terpenes
activity (biology)
2016
32 Citations

Clerodane diterpenes: Sources, structures, and biological activities

Li, R., Morris-Natschke, S. L. & Lee, K. H., Oct 1 2016, In : Natural Product Reports. 33, 10, p. 1166-1226 61 p.

Research output: Contribution to journalReview article

Clerodane Diterpenes
Bioactivity
Opioid Receptors
Salvia
Diterpenes
2014
20 Citations

Anticancer principles from medicinal Piper (Hú Jiāo) plants

Wang, Y. H., Morris-Natschke, S., Yang, J., Niu, H. M., Long, C. L. & Lee, K. H., Jan 1 2014, In : Journal of Traditional and Complementary Medicine. 4, 1, p. 8-16 9 p.

Research output: Contribution to journalReview article

Piper
Piperaceae
Neoplasms
Poisons
Traditional Medicine
2012
118 Citations

Recent discovery of plant-derived anti-diabetic natural products

Hung, H. Y., Qian, K., Morris-Natschke, S. L., Hsu, C. S. & Lee, K. H., May 2012, In : Natural Product Reports. 29, 5, p. 580-606 27 p.

Research output: Contribution to journalReview article

Medical problems
Biological Products
Type 2 Diabetes Mellitus
Literature
Patents
14 Citations

Recent progress of research on herbal products used in traditional chinese medicine: The herbs belonging to the divine husbandman′s herbal foundation canon ( shén nóng běn co jīng)

Lee, K. H., Morris-Natschke, S., Qian, K., Dong, Y., Yang, X., Zhou, T., Belding, E., Wu, S. F., Wada, K. & Akiyama, T., Jan 1 2012, In : Journal of Traditional and Complementary Medicine. 2, 1, p. 6-26 21 p.

Research output: Contribution to journalReview article

Materia Medica
Chinese Traditional Medicine
Research
2011
108 Citations
Biosynthesis
Therapeutics
Abietane Diterpenes
Salvia miltiorrhiza
Biosynthetic Pathways
2010
179 Citations

Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach

Lee, K. H., Mar 26 2010, In : Journal of Natural Products. 73, 3, p. 500-516 17 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
Biological Products
Phase II Clinical Trials
Clinical Trials
Quassins
2009
62 Citations

HIV entry inhibitors and their potential in HIV therapy

Qian, K., Morris-Natschke, S. L. & Lee, K. H., Mar 2009, In : Medicinal Research Reviews. 29, 2, p. 369-393 25 p.

Research output: Contribution to journalReview article

HIV Fusion Inhibitors
Anti-HIV Agents
HIV
Clinical Trials
Viruses
97 Citations

Plant-derived triterpenoids and analogues as antitumor and Anti-HIV agents

Kuo, R. Y., Qian, K., Morris-Natschke, S. L. & Lee, K. H. 2009 In : Natural Product Reports. 26, 10, p. 1321-1344 24 p.

Research output: Contribution to journalReview article

Anti-HIV Agents
Structure-Activity Relationship
Scaffolds
HIV
Derivatives
2008
109 Citations

Plant-derived natural product research aimed at new drug discovery

Itokawa, H., Morris-Natschke, S. L., Akiyama, T. & Lee, K. H., Jul 1 2008, In : Journal of Natural Medicines. 62, 3, p. 263-280 18 p.

Research output: Contribution to journalReview article

Dietary supplements
Lead compounds
Bioassay
Drug Discovery
Fractionation
114 Citations

Recent advances in the investigation of curcuminoids

Itokawa, H., Shi, Q., Akiyama, T., Morris-Natschke, S. L. & Lee, K. H. Sep 17 2008 In : Chinese Medicine. 3, 11

Research output: Contribution to journalReview article

Curcumin
Curcuma
Zingiberaceae
Rhizome
Sesquiterpenes
2007
70 Citations

New developments in natural products-based anti-AIDS research

Yu, D., Morris-Natschke, S. L. & Lee, K. H. Jan 1 2007 In : Medicinal Research Reviews. 27, 1, p. 108-132 25 p.

Research output: Contribution to journalReview article

Biological Products
Acquired Immunodeficiency Syndrome
Research
HIV
Lead compounds
334 Citations

New developments in the chemistry and biology of the bioactive constituents of Tanshen

Wang, X., Morris-Natschke, S. L. & Lee, K. H., Jan 1 2007, In : Medicinal Research Reviews. 27, 1, p. 133-148 16 p.

Research output: Contribution to journalReview article

Antioxidants
Salvia miltiorrhiza
Rhizome
Chinese Traditional Medicine
Bioactivity
2005
39 Citations

The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV

Yu, D., Wild, C. T., Martin, D. E., Morris-Natschke, S. L., Chen, C. H., Allaway, G. P. & Lee, K. H., Jun 1 2005, In : Expert Opinion on Investigational Drugs. 14, 6, p. 681-693 13 p.

Research output: Contribution to journalReview article

Biological Products
Anti-HIV Agents
HIV-1
HIV
Reverse Transcriptase Inhibitors
2003
47 Citations

Plant-derived terpenoids and analogues as anti-HIV agents.

Sun, I. C., Kashiwada, Y., Morris-Natschke, S. L. & Lee, K. H., 2003, In : Current Topics in Medicinal Chemistry. 3, 2, p. 155-169 15 p.

Research output: Contribution to journalReview article

Anti-HIV Agents
Triterpenes
Terpenes
Diterpenes
Cucurbitacins
2 Citations
Anti-HIV Agents
Biological Products
Medicine
Bioelectric potentials
Natural resources
312 Citations

Recent progress in the development of coumarin derivatives as potent anti-HIV agents

Yu, D., Suzuki, M., Xie, L., Morris-Natschke, S. L. & Lee, K. H., May 2003, In : Medicinal Research Reviews. 23, 3, p. 322-345 24 p.

Research output: Contribution to journalReview article

Anti-HIV Agents
Coumarins
calanolide A
HIV
Phytochemicals
2000
14 Citations

Current perspectives on Chinese medicines and dietary supplements in China, Japan and the United States

Lee, K. H., Wang, H. K., Itokawa, H. & Morris-Natschke, S. L., Dec 2000, In : Journal of Food and Drug Analysis. 8, 4, p. 219-228 10 p.

Research output: Contribution to journalReview article

Dietary Supplements
Herbal Medicine
herbal medicines
dietary supplements
China
90 Citations

Research and future trends in the pharmaceutical development of medicinal herbs from Chinese medicine

Lee, K. H., Jan 1 2000, In : Public health nutrition. 3, 4 A, p. 515-522 8 p.

Research output: Contribution to journalReview article

Medicinal Plants
medicinal plants
medicine
Medicine
drugs
1999
110 Citations

Anticancer drug design based on plant-derived natural products

Lee, K. H., Jan 1 1999, In : Journal of Biomedical Science. 6, 4, p. 236-250 15 p.

Research output: Contribution to journalReview article

Drug Design
Structure-Activity Relationship
Bioactivity
Biological Products
Research
96 Citations

Novel antitumor agents from higher plants

Kuo-Hsiung, L., 1999, In : Medicinal Research Reviews. 19, 6, p. 569-596 28 p.

Research output: Contribution to journalReview article

Biological Products
Antineoplastic Agents
Quassins
Podophyllotoxin
Derivatives
34 Citations

Recent advances in the discovery and development of quinolones and analogs as antitumor agents

Xia, Y., Yang, Z. Y., Morris-Natschke, S. L. & Lee, K. H., Apr 15 1999, In : Current Medicinal Chemistry. 6, 3, p. 179-194 16 p.

Research output: Contribution to journalReview article

Quinolones
Antineoplastic Agents
DNA Gyrase
Topoisomerase II Inhibitors
Antimitotic Agents
1998
117 Citations

Recent progress in the development of tubulin inhibitors as antimitotic antitumor agents

Shi, Q., Chen, K., Morris-Natschke, S. L. & Lee, K. H., Jun 1998, In : Current Pharmaceutical Design. 4, 3, p. 219-248 30 p.

Research output: Contribution to journalReview article

Tubulin Modulators
Antimitotic Agents
Antineoplastic Agents
Colchicine
docetaxel
1997
14 Citations

Plant-derived anticancer agents and their analogs currently in clinical use or in clinical trials

Wang, H. K. & Lee, K. H., 1997, In : Botanical Bulletin of Academia Sinica. 38, 4, p. 225-235 11 p.

Research output: Contribution to journalReview article

antineoplastic agents
clinical trials
drugs
plant products
history
157 Citations

Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents

Wang, H. K., Morris-Natschke, S. L. & Lee, K. H., Jul 1 1997, In : Medicinal Research Reviews. 17, 4, p. 367-425 59 p.

Research output: Contribution to journalReview article

Topoisomerase Inhibitors
Cultured Tumor Cells
Computer-Aided Design
Camptothecin
Type II DNA Topoisomerase
1995
19 Citations

Current status of bioanalysis of etoposide and related compounds

Lee, K. H. & Wang, H. K., 1995, In : Journal of Food and Drug Analysis. 3, 4, p. 209-232 24 p.

Research output: Contribution to journalReview article

Etoposide
metabolites
pharmacokinetics
mechanism of action
Pharmacokinetics