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  • 3 Similar Profiles
Hepatocytes Medicine & Life Sciences
Liver Medicine & Life Sciences
Rats Chemical Compounds
Pharmacokinetics Medicine & Life Sciences
Bile Acids and Salts Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Taurocholic Acid Medicine & Life Sciences
Bile Medicine & Life Sciences

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Projects 1991 2018

North Carolina Translational & Clinical Sciences Institute (NC TraCS)

Fraser, M. W., Sims, C. E., Mostafa, J., Wohl, D. A., Weber, D. J., Bangdiwala, S. I., Carey, T. S., Phillips, C. L., Miller, W. C., Jonsson-Funk, M. L., Jones, S. W., Beck, J. D., Mauriello, S. M., Retsch-Bogart, G. Z., Falk, R. J., Jordan, J. M., Ammerman, A. S., Carpenter, W. R., Edwards, L. J., Garrett, J. M., Coyne-Beasley, T., Henderson, G. E., Stewart, P. W., Davis, A. M., Evans, J. P., Gilmore, J. H., Gaynes, B. N., Brookhart, M. A., Sleath, B. L., Offenbacher, S., Marzluff, W. F., Topal, M. D., Orringer, E. P., Qaqish, B. F., Leigh, M. W., Peden, D. B., Buse, J. B., Tolleson-Rinehart, S., Ransohoff, D. F., Funkhouser, W. K., Egan, T. M., Cai, J., Truong, K. N., Brouwer, K. L., Boucher, R. C., Sen, P. K., Reuland, D. S., Donahue, K. E., Weiner, B. J., Watkins, P. B., Lin, W., Perrin, E. M., Magnuson, T. R., Corbie-Smith, G. M., Duncan, J. A., Weinberger, M., Zeng, D., Meshnick, S. R., Ibrahim, J. G., Dilworth-Anderson, P., Johnson, G. L., Walker, R. L., Viera, A. J., Glickman, S. W., Halladay, J. R., Rennie, S. M., Key, N. S., Rubin, J. E., Kosorok, M. R., Zhu, H., Bair, E., Henning, S. J., Mackman, N., Fine, J. P., Mayer-Davis, E. J., Stuermer, T. H. R., Davis, R. M., Park, S. I., Wu, M. C., Carpenter, D. M., Fang, G., Weaver, M. A., Lin, F., Davis, S. M., Shea, C. M., Carter-Edwards, L., Dennis, A. M., Fisher, J. A., Golightly, Y. M., Hingtgen, S. D., Smith, A. M., Tan, J. T., Asher, G. N., Barritt, A. S., Blouin, R., Buchbinder, M., Hurt, C., Juengst, E. T., Mendoza, L. C., Reeve, B., Roman Isler, M. D., Wood, W. A., Ahalt, S., Agans, R. P., Dave, G. J., Lightfoot, A. F., Zhou, H., Skinner, A. C., Wilhelmsen, K. C., Song, L., Fischer, W. A., Peery, A. F., Powers, K. A., Ryan, A. E., Otey, C. A., Donaldson, S. H., Leeman, J., Kashuba, A. D., Gomez, S. M., Chung, A. E., Meyer, A. M., Parrott, M. C., Toles, M. P., Schmitt, C., Nichols, H. B. & Moran, T. P.

NIH National Center for Advancing Translational Sciences (NCATS)


Project: Research project

Annual Reports

Research Output 1980 2018

A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

Karageorgis, A., Lenhard, S. C., Yerby, B., Forsgren, M. F., Liachenko, S., Johansson, E., Pilling, M. A., Peterson, R. A., Yang, X., Williams, D. P., Ungersma, S. E., Morgan, R. E., Brouwer, K. L. R., Jucker, B. M. & Hockings, P. D. May 1 2018 In : PloS one. 13, 5, e0197213

Research output: Contribution to journalArticle

Slip forming
Thallium alloys
magnetic resonance imaging

Bile Acids as Potential Biomarkers to Assess Liver Impairment in Polycystic Kidney Disease

Brock, W. J., Beaudoin, J. J., Slizgi, J. R., Su, M., Jia, W., Roth, S. E. & Brouwer, K. L. R. Mar 1 2018 In : International Journal of Toxicology. 37, 2, p. 144-154 11 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Bile Acids and Salts
Quality of service
Chenodeoxycholic Acid
Taurocholic Acid
Bile Acids and Salts
2 Citations

In vitro to in vivo extrapolation for high throughput prioritization and decision making

Bell, S. M. , Chang, X. , Wambaugh, J. F. , Allen, D. G. , Bartels, M. , Brouwer, K. L. R. , Casey, W. M. , Choksi, N. , Ferguson, S. S. , Fraczkiewicz, G. , Jarabek, A. M. , Ke, A. , Lumen, A. , Lynn, S. G. , Paini, A. , Price, P. S. , Ring, C. , Simon, T. W. , Sipes, N. S. , Sprankle, C. S. & 4 others Strickland, J., Troutman, J., Wetmore, B. A. & Kleinstreuer, N. C. Mar 1 2018 In : Toxicology in Vitro. 47, p. 213-227 15 p.

Research output: Contribution to journalReview article

Decision Making
Chemical Safety
United States Environmental Protection Agency
Bile Acids and Salts
Wounds and Injuries
Taurocholic Acid
Pharmaceutical Preparations