• 1394 Citations
  • 15 h-Index
20042018
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Dependovirus Medicine & Life Sciences
Capsid Medicine & Life Sciences
Genetic Therapy Medicine & Life Sciences
Virion Medicine & Life Sciences
Osteoarthritis Medicine & Life Sciences
capsid Agriculture & Biology
virion Agriculture & Biology
pathogenicity Agriculture & Biology

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Projects 2004 2018

Dependovirus
Bioreactors
Genetic Therapy
Research Personnel
Hemophilia B
Genetic Therapy
Research Personnel
Equipment and Supplies
Retinal Degeneration
Dystrophin
Congenital Structural Myopathies
Genetic Therapy
Canidae
Respiratory Muscles
Muscle Weakness
Dependovirus
Factor VIII
Hemophilia A
Genetic Therapy
Factor IX
Dependovirus
Factor VIII
Hemophilia A
Genetic Therapy
Factor IX

Research Output 2005 2018

  • 1394 Citations
  • 15 h-Index
  • 16 Article
  • 1 Chapter
  • 1 Review article

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

Tan, Y. Z., Aiyer, S., Mietzsch, M., Hull, J. A., McKenna, R., Grieger, J. C., Samulski, R. J., Baker, T. S., Agbandje-McKenna, M. & Lyumkis, D., Dec 1 2018, In : Nature communications. 9, 1, 3628.

Research output: Contribution to journalArticle

Gene transfer
Viruses
Numerical methods
Microscopes
Gene therapy
48 Citations

Manufacturing of recombinant adeno-associated viral vectors for clinical trials

Clément, N. & Grieger, J. C., Mar 16 2016, In : Molecular Therapy - Methods and Clinical Development. 3, 1 p., 16002.

Research output: Contribution to journalArticle

Dependovirus
Clinical Trials
Patient Transfer
Transgenes
Genetic Therapy
40 Citations
Dependovirus
HEK293 Cells
Transfection
Culture Media
Suspensions
13 Citations

Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model

Wang, G., Evans, C. H., Benson, J. M., Hutt, J. A., Seagrave, J. C., Wilder, J. A., Grieger, J. C., Samulski, R. J. & Terse, P. S., Mar 16 2016, In : Molecular Therapy - Methods and Clinical Development. 3, 1 p.

Research output: Contribution to journalArticle

Iodoacetates
Intra-Articular Injections
Osteoarthritis
Interleukin-1 Receptors
Knee
44 Citations

Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: Preclinical evaluation supporting an ongoing adeno-associated virus clinical trial

Monahan, P. E., Sun, J., Gui, T., Hu, G., Hannah, W. B., Wichlan, D. G., Wu, Z., Grieger, J. C., Li, C., Suwanmanee, T., Stafford, D. W., Booth, C. J., Samulski, J. J., Kafri, T., McPhee, S. W. J. & Samulski, R. J., Feb 1 2015, In : Human Gene Therapy. 26, 2, p. 69-81 13 p.

Research output: Contribution to journalArticle

Hemophilia B
Dependovirus
Factor IX
Genetic Therapy
Clinical Trials