Jonathan Cummings Schisler

    • 1545 Citations
    • 22 h-Index
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    • 9 Similar Profiles
    Ubiquitin Medicine & Life Sciences
    Islets of Langerhans Medicine & Life Sciences
    Cardiomegaly Medicine & Life Sciences
    Ligases Medicine & Life Sciences
    Proteasome Endopeptidase Complex Medicine & Life Sciences
    Transcription Factors Medicine & Life Sciences
    Gene expression Chemical Compounds
    Fingers Medicine & Life Sciences

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    Projects 2000 2020

    Research Output 2001 2018

    Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP

    Tang, M. B., Li, Y. S., Li, S. H., Cheng, Y., Zhang, S., Luo, H. Y., Mao, C. Y., Hu, Z. W., Schisler, J. C., Shi, C. H. & Xu, Y. M., Dec 1 2018, In : Scientific Reports. 8, 1, 6379.

    Research output: Contribution to journalArticle

    HSC70 Heat-Shock Proteins
    Ubiquitin-Protein Ligases
    Brain Ischemia
    Receptor-Interacting Protein Serine-Threonine Kinases

    Applicability of precision medicine approaches to managing hypertension in rural populations

    Halladay, J. R., Lenhart, K. C., Robasky, K., Jones, W., Homan, W. F., Cummings, D. M., Cené, C. W., Hinderliter, A. L., Miller, C. L., Donahue, K. E., Garcia, B. A., Keyserling, T. C., Ammerman, A. S., Patterson, C., Dewalt, D. A., Johnston, L. F., Willis, M. S. & Schisler, J. C., Jun 1 2018, In : Journal of Personalized Medicine. 8, 2, 16.

    Research output: Contribution to journalArticle

    Precision Medicine
    Rural Population
    Blood Pressure
    Single Nucleotide Polymorphism
    2 Citations

    CHIP regulates aquaporin-2 quality control and body water homeostasis

    Wu, Q., Moeller, H. B., Stevens, D. A., Sanchez-Hodge, R., Childers, G., Kortenoeven, M. L. A., Cheng, L., Rosenbaek, L. L., Rubel, C., Patterson, C., Pisitkun, T., Schisler, J. C. & Fenton, R. A., Mar 1 2018, In : Journal of the American Society of Nephrology. 29, 3, p. 936-948 13 p.

    Research output: Contribution to journalArticle

    Aquaporin 2
    Body Water
    Quality Control

    Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16

    Shi, C. H., Rubel, C., Soss, S. E., Sanchez-Hodge, R., Zhang, S., Madrigal, S. C., Ravi, S., McDonough, H., Page, R. C., Chazin, W. J., Patterson, C., Mao, C. Y., Willis, M. S., Luo, H. Y., Li, Y. S., Stevens, D. A., Tang, M. B., Du, P., Wang, Y. H., Hu, Z. W. & 2 othersXu, Y. M. & Schisler, J. C., Sep 1 2018, In : PLoS genetics. 14, 9, e1007664.

    Research output: Contribution to journalArticle


    Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo

    Mota, R., Parry, T. L., Yates, C. C., Qiang, Z., Eaton, S. C., Mwiza, J. M., Tulasi, D., Schisler, J. C., Patterson, C., Zaglia, T., Sandri, M. & Willis, M. S., Jul 1 2018, In : American Journal of Pathology. 188, 7, p. 1676-1692 17 p.

    Research output: Contribution to journalArticle

    Cardiac Myocytes
    Matrix Metalloproteinase 8