• 8144 Citations
  • 45 h-Index
1990 …2018
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  • 15 Similar Profiles
Type C Phospholipases Medicine & Life Sciences
Chemical activation Chemical Compounds
rho GTP-Binding Proteins Medicine & Life Sciences
Guanine Nucleotide Exchange Factors Medicine & Life Sciences
GTP Phosphohydrolases Chemical Compounds
Proteins Medicine & Life Sciences
Isoenzymes Medicine & Life Sciences
Guanine Nucleotides Medicine & Life Sciences

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Projects 1995 2018

Research Output 1990 2018

1 Citations

A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes

Huang, W., Wang, X., Endo-Streeter, S., Barrett, M., Waybright, J., Wohlfeld, C., Hajicek, N., Harden, T. K., Sondek, J. E. & Zhang, Q., Jan 1 2018, In : Journal of Biological Chemistry. 293, 5, p. 1728-1735 8 p.

Research output: Contribution to journalArticle

Type C Phospholipases
Programmable logic controllers
Chemical activation
2 Citations

Calcium-induced structural rearrangements release autoinhibition in the Rap-GEF CalDAG-GEFI

Cook, A. A., Deng, W., Ren, J., Li, R., Sondek, J. E. & Bergmeier, W., Jan 1 2018, In : Journal of Biological Chemistry. 293, 22, p. 8521-8529 9 p.

Research output: Contribution to journalArticle

EF Hand Motifs
Blood Platelets
22 Citations

TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis

Nishimura, M. T., Anderson, R. G., Cherkis, K. A., Law, T. F., Liu, Q. L., Machius, M., Nimchuk, Z. L., Yang, L., Chung, E. H., El Kasmi, F., Hyunh, M., Nishimura, E. O., Sondek, J. E. & Dangl, J. L., Mar 7 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 10, p. E2053-E2062

Research output: Contribution to journalArticle

Interleukin Receptors
Cell Death
Plant Immunity
3 Citations

A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylation

Ren, J., Cook, A. A., Bergmeier, W. & Sondek, J., May 20 2016, In : Biochemical and Biophysical Research Communications. 474, 1, p. 193-198 6 p.

Research output: Contribution to journalArticle

Chemical activation
Guanine Nucleotide Exchange Factors
Signal transduction
21 Citations

Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

Lozano, M. L., Cook, A., Bastida, J. M., Paul, D. S., Iruin, G., Cid, A. R., Adan-Pedroso, R., González-Porras, J. R., Hernández-Rivas, J. M., Fletcher, S. J., Johnson, B., Morgan, N., Ferrer-Marin, F., Vicente, V., Sondek, J., Watson, S. P., Bergmeier, W. & Rivera, J., Sep 1 2016, In : Blood. 128, 9, p. 1282-1289 8 p.

Research output: Contribution to journalArticle

Platelet Activation
Blood Platelets
Chemical activation