• 6309 Citations
  • 43 h-Index
1983 …2018
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  • 3 Similar Profiles
Heparitin Sulfate Medicine & Life Sciences
Sulfotransferases Medicine & Life Sciences
Heparin Medicine & Life Sciences
Oligosaccharides Chemical Compounds
Anticoagulants Medicine & Life Sciences
Biosynthesis Chemical Compounds
Polysaccharides Medicine & Life Sciences
Substrate Specificity Medicine & Life Sciences

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Projects 2001 2018

Research Output 1983 2018

3-O sulfation of heparin leads to hepatotropism and longer circulatory half-life

Miller, C. M., Xu, Y., Kudrna, K. M., Hass, B. E., Kellar, B. M., Egger, A. W., Liu, J. & Harris, E. N., Jul 1 2018, In : Thrombosis Research. 167, p. 80-87 8 p.

Research output: Contribution to journalArticle

Half-Life
Heparin
Endocytosis
Knockout Mice
Liver

A Traveling Wave Ion Mobility Spectrometry (TWIMS) Study of the Robo1-Heparan Sulfate Interaction

Zhao, Y., Yang, J. Y., Thieker, D. F., Xu, Y., Zong, C., Boons, G. J., Liu, J., Woods, R. J., Moremen, K. W. & Amster, I. J., Jun 1 2018, In : Journal of the American Society for Mass Spectrometry. 29, 6, p. 1153-1165 13 p.

Research output: Contribution to journalArticle

Ion mobility spectrometers
Sulfur Compounds
Heparitin Sulfate
Glycosaminoglycans
Binding energy
2 Citations

Controlled Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides

Lu, W., Zong, C., Chopra, P., Pepi, L. E., Xu, Y., Amster, I. J., Liu, J. & Boons, G. J., May 4 2018, In : Angewandte Chemie - International Edition. 57, 19, p. 5340-5344 5 p.

Research output: Contribution to journalArticle

Sulfur Compounds
Heparitin Sulfate
Chemical modification
Oligosaccharides
Nanostructured materials

Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase

Thieker, D. F., Xu, Y., Chapla, D., Nora, C., Qiu, H., Felix, T., Wang, L., Moremen, K. W., Liu, J., Esko, J. D. & Woods, R. J., Dec 1 2018, In : Scientific Reports. 8, 1, 11832.

Research output: Contribution to journalArticle

Sulfotransferases
Heparitin Sulfate
Oligosaccharides
Biosynthesis
Cell signaling
2 Citations

New tools for carbohydrate sulfation analysis: Heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., Papy-Garcia, D., Chantepie, S., Pagadala, V., Liu, J., Wells, C., Drewry, D. H., Zuercher, W. J., Berry, N. G., Fernig, D. G. & Eyers, P. A., Aug 14 2018, In : Biochemical Journal. 475, 15, p. 2417-2433 17 p.

Research output: Contribution to journalArticle

Sulfotransferases
Heparitin Sulfate
Protein Kinase Inhibitors
Carbohydrates
Molecules