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Azides Chemical Compounds
Ketones Chemical Compounds
Lactams Chemical Compounds
Amides Chemical Compounds
Substrates Chemical Compounds
Nitrogen Chemical Compounds
Molecules Chemical Compounds
Lewis Acids Chemical Compounds

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Projects 2015 2017

Research Output 1980 2016

2 Citations

Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy

Slone, S., Anthony, S. R., Wu, X., Benoit, J. B., Aube, J., Xu, L. & Tranter, M. Nov 1 2016 In : Cellular Signalling. 28, 11, p. 1735-1741 7 p.

Research output: Research - peer-reviewArticle

p38 Mitogen-Activated Protein Kinases
Cardiac Myocytes
NFATC Transcription Factors
4 Citations

DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites

Gowthaman, R., Miller, S. A., Rogers, S., Khowsathit, J., Lan, L., Bai, N., Johnson, D. K., Liu, C., Xu, L., Anbanandam, A., Aubé, J., Roy, A. & Karanicolas, J. May 12 2016 In : Journal of Medicinal Chemistry. 59, 9, p. 4152-4170 19 p.

Research output: Research - peer-reviewArticle

Pharmaceutical Preparations
Protein Binding

Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples

McLeod, M. C., Aubé, J. & Frankowski, K. J. Jan 1 2016 In : Bioorganic and Medicinal Chemistry Letters. 26, 23, p. 5689-5694 6 p.

Research output: Research - peer-reviewArticle

sigma Receptors
sigma-2 receptor
Structure-Activity Relationship
2 Citations

Efficient access to sp3-rich tricyclic amine scaffolds through Diels-Alder reactions of azide-containing silyloxydienes

McLeod, M. C. & Aubé, J. Jun 30 2016 In : Tetrahedron. 72, 26, p. 3766-3774 9 p.

Research output: Research - peer-reviewArticle

Cycloaddition Reaction
8 Citations

Hexafluoro-2-propanol-Promoted Intermolecular Friedel-Crafts Acylation Reaction

Vekariya, R. H. & Aubé, J. Aug 5 2016 In : Organic Letters. 18, 15, p. 3534-3537 4 p.

Research output: Research - peer-reviewArticle

room temperature