• 16589 Citations
  • 67 h-Index
1971 …2020
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  • 6 Similar Profiles
Ryanodine Receptor Calcium Release Channel Medicine & Life Sciences
Sarcoplasmic Reticulum Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Muscle Chemical Compounds
Ryanodine Medicine & Life Sciences
Calmodulin Medicine & Life Sciences
Calcium Channels Medicine & Life Sciences
Myocardium Medicine & Life Sciences

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Projects 1976 2020

Research Output 1971 2018

Ca2-mediated activation of the skeletal-muscle ryanodine receptor ion channel

Xu, L., Chirasani, V. R., Carter, J. S., Pasek, D. A., Dokholyan, N. V., Yamaguchi, N. & Meissner, G. W., Jan 1 2018, In : Journal of Biological Chemistry. 293, 50, p. 19501-19509 9 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Ion Channels
Muscle
Skeletal Muscle
Chemical activation
1 Citations

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to ytosolic and luminal Ca2+

Xu, L., Mowrey, D. D., Chirasani, V. R., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G. W., Jan 1 2018, In : Journal of Biological Chemistry. 293, 6, p. 2015-2028 14 p.

Research output: Contribution to journalArticle

S 6
Ryanodine Receptor Calcium Release Channel
Linings
Muscle
Skeletal Muscle
4 Citations

Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor

Mowrey, D. D., Xu, L., Mei, Y., Pasek, D. A., Meissner, G. W. & Dokholyan, N. V., Jan 1 2017, In : Journal of Biological Chemistry. 292, 31, p. 12947-12958 12 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Muscle
Skeletal Muscle
Ions
Constriction
12 Citations

The structural basis of ryanodine receptor ion channel function

Meissner, G., Dec 1 2017, In : Journal of General Physiology. 149, 12, p. 1065-1089 25 p.

Research output: Contribution to journalReview article

Ryanodine Receptor Calcium Release Channel
Ion Channels
Cytoplasmic Structures
Skeletal Muscle
Myocardium
2 Citations

Two EF-hand motifs in ryanodine receptor calcium release channels contribute to isoform-specific regulation by calmodulin

Xu, L., Gomez, A. C., Pasek, D. A., Meissner, G. & Yamaguchi, N., Sep 1 2017, In : Cell Calcium. 66, p. 62-70 9 p.

Research output: Contribution to journalArticle

EF Hand Motifs
Ryanodine Receptor Calcium Release Channel
Calmodulin
Protein Isoforms
Amino Acids