• 16452 Citations
  • 68 h-Index
1971 …2020
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  • 7 Similar Profiles
Ryanodine Receptor Calcium Release Channel Medicine & Life Sciences
Sarcoplasmic Reticulum Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences
Muscle Chemical Compounds
Ryanodine Medicine & Life Sciences
Calmodulin Medicine & Life Sciences
Calcium Channels Medicine & Life Sciences
Myocardium Medicine & Life Sciences

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Projects 1976 2020

Research Output 1971 2018

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to ytosolic and luminal Ca2+

Xu, L., Mowrey, D. D., Chirasani, V. R., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 6, p. 2015-2028 14 p.

Research output: Contribution to journalArticle

S 6
Ryanodine Receptor Calcium Release Channel
Linings
Muscle
Skeletal Muscle
3 Citations

Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor

Mowrey, D. D., Xu, L., Mei, Y., Pasek, D. A., Meissner, G. & Dokholyan, N. V., Jan 1 2017, In : Journal of Biological Chemistry. 292, 31, p. 12947-12958 12 p.

Research output: Contribution to journalArticle

8 Citations

The structural basis of ryanodine receptor ion channel function

Meissner, G., Dec 1 2017, In : Journal of General Physiology. 149, 12, p. 1065-1089 25 p.

Research output: Contribution to journalReview article

Ryanodine Receptor Calcium Release Channel
Ion Channels
Cytoplasmic Structures
Skeletal Muscle
Myocardium
2 Citations

Two EF-hand motifs in ryanodine receptor calcium release channels contribute to isoform-specific regulation by calmodulin

Xu, L., Gomez, A. C., Pasek, D. A., Meissner, G. & Yamaguchi, N., Sep 1 2017, In : Cell Calcium. 66, p. 62-70 9 p.

Research output: Contribution to journalArticle

EF Hand Motifs
Excitation Contraction Coupling
Ryanodine Receptor Calcium Release Channel
Calmodulin
Myocardium
9 Citations

Channel gating dependence on pore lining helix glycine residues in skeletal muscle ryanodine receptor

Mei, Y., Xu, L., Mowrey, D. D., Giraldez, R. M., Wang, Y., Pasek, D. A., Dokholyan, N. V. & Meissner, G., Jul 10 2015, In : Journal of Biological Chemistry. 290, 28, p. 17535-17545 11 p.

Research output: Contribution to journalArticle

Ryanodine Receptor Calcium Release Channel
Linings
Glycine
Muscle
Skeletal Muscle