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  • 6 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
MAP Kinase Kinase Kinases Medicine & Life Sciences
Adenylyl Cyclases Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences

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Projects 1981 2018

Triple Negative Breast Neoplasms
Breast Neoplasms
Therapeutics
Phosphotransferases
Drug Therapy
Triple Negative Breast Neoplasms
Mitogen-Activated Protein Kinase Kinases
Epigenomics
Therapeutics
MAP Kinase Kinase Kinases
Neurofibromatosis 1
Neoplasms
Exome
Molecular Biology
Mass Spectrometry

Research Output 1974 2017

3 Citations

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma: Neuro Oncol

McNeill, R. S. , Canoutas, D. A. , Stuhlmiller, T. J. , Dhruv, H. D. , Irvin, D. M. , Bash, R. E. , Angus, S. P. , Herring, L. E. , Simon, J. M. , Skinner, K. R. , Limas, J. C. , Chen, X. , Schmid, R. S. , Siegel, M. B. , Van Swearingen, A. E. D. , Hadler, M. J. , Sulman, E. P. , Sarkaria, J. N. , Anders, C. K. , Graves, L. M. & 3 others Berens, M. E., Johnson, G. L. & Miller, C. R. Apr 6 2017 In : Neuro-Oncology. 19, 11, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Glioblastoma
Protein Kinase Inhibitors
Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase Kinases
2 Citations

Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer: Neuro Oncol

Van Swearingen, A. E. D., Sambade, M. J., Siegel, M. B., Sud, S., McNeill, R. S., Bevill, S. M., Chen, X., Bash, R. E., Mounsey, L., Golitz, B. T., Santos, C., Deal, A. M., Parker, J. S., Rashid, N., Miller, C. R., Johnson, G. L. & Anders, C. K. May 10 2017 In : Neuro-Oncology. 19, 11, p. 1481-1493 13 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Mitogen-Activated Protein Kinase Kinases
Phosphatidylinositol 3-Kinases
Phosphotransferases
Brain Neoplasms
18 Citations

Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex

Zawistowski, J. S. , Bevill, S. M. , Goulet, D. R. , Stuhlmiller, T. J. , Beltran, A. S. , Olivares-Quintero, J. F. , Singh, D. , Sciaky, N. , Parker, J. S. , Rashid, N. U. , Chen, X. , Duncan, J. S. , Whittle, M. C. , Angus, S. P. , Velarde, S. H. , Golitz, B. T. , He, X. , Santos, C. , Darr, D. B. , Gallagher, K. & 5 others Graves, L. M., Perou, C. M., Carey, L. A., Shelton Earp, H. & Johnson, G. L. Mar 1 2017 In : Cancer Discovery. 7, 3, p. 302-321 20 p.

Research output: Contribution to journalArticle

Positive Transcriptional Elongation Factor B
Mitogen-Activated Protein Kinase Kinases
Triple Negative Breast Neoplasms
Receptor Protein-Tyrosine Kinases
Neoplasms
5 Citations

Kinome profiling identifies druggable targets for novel human cytomegalovirus (HCMV) antivirals

Arend, K. C., Lenarcic, E. M., Vincent, H. A., Rashid, N., Lazear, E., McDonald, I. M., Gilbert, T. S. K., East, M. P., Herring, L. E., Johnson, G. L., Graves, L. M. & Moorman, N. J. Apr 1 2017 In : Molecular and Cellular Proteomics. 16, 4, p. S263-S276

Research output: Contribution to journalArticle

Cytomegalovirus
Antiviral Agents
Phosphotransferases
Viruses
Mass spectrometry

Landscaping a chromatin response to MEK inhibition

Zawistowski;, J. S., Goulet;, D. R. & Johnson;, G. L. Apr 18 2017 In : Cell Cycle. 16, 8, p. 731-732 2 p.

Research output: Contribution to journalComment/debate

Positive Transcriptional Elongation Factor B
Mitogen-Activated Protein Kinase Kinases
Chromatin