• 30296 Citations
  • 87 h-Index
1974 …2018
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  • 6 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
MAP Kinase Kinase Kinases Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Adenylyl Cyclases Medicine & Life Sciences
JNK Mitogen-Activated Protein Kinases Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences

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Projects 1981 2018

Triple Negative Breast Neoplasms
Breast Neoplasms
Therapeutics
Phosphotransferases
Drug Therapy
Neurofibromatosis 1
Neoplasms
Exome
Molecular Biology
Mass Spectrometry
Triple Negative Breast Neoplasms
Mitogen-Activated Protein Kinase Kinases
Epigenomics
Therapeutics
MAP Kinase Kinase Kinases

Research Output 1974 2018

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

Krulikas, L. J., McDonald, I. M., Lee, B., Okumu, D. O., East, M. P., Gilbert, T. S. K., Herring, L. E., Golitz, B. T., Wells, C. I., Axtman, A. D., Zuercher, W. J., Willson, T. M., Kireev, D., Yeh, J. J., Johnson, G. L., Baines, A. T. & Graves, L. M., Sep 1 2018, In : SLAS Discovery. 23, 8, p. 850-861 12 p.

Research output: Contribution to journalArticle

gemcitabine
Preclinical Drug Evaluations
Cell growth
Pancreatic Neoplasms
Screening
1 Citations

Competitive Kinase Enrichment Proteomics Reveals that Abemaciclib Inhibits GSK3b and Activates WNT Signaling

Cousins, E. M., Goldfarb, D., Yan, F., Roques, J., Darr, D., Johnson, G. L. & Major, M. B., Feb 1 2018, In : Molecular Cancer Research. 16, 2, p. 333-344 12 p.

Research output: Contribution to journalArticle

Proteomics
Phosphotransferases
Mass Spectrometry
Catenins
Cyclin-Dependent Kinase 6

EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma

Angus, S. P., Oblinger, J. L., Stuhlmiller, T. J., DeSouza, P. A., Beauchamp, R. L., Witt, L., Chen, X., Jordan, J. T., Gilbert, T. S. K., Stemmer-Rachamimov, A., Gusella, J. F., Plotkin, S. R., Haggarty, S. J., Chang, L. S., Johnson, G. L. & Ramesh, V., Jan 1 2018, In : Neuro-Oncology. 20, 9, p. 1185-1196 12 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Meningioma
src-Family Kinases
Null Lymphocytes
Receptor Protein-Tyrosine Kinases
2 Citations

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase

Asquith, C. R. M., Laitinen, T., Bennett, J. M., Godoi, P. H., East, M. P., Tizzard, G. J., Graves, L. M., Johnson, G. L., Dornsife, R. E., Wells, C. I., Elkins, J. M., Willson, T. M. & Zuercher, W. J., Jan 8 2018, In : ChemMedChem. 13, 1, p. 48-66 19 p.

Research output: Contribution to journalArticle

Cyclin G
Phosphotransferases
Anti-Bacterial Agents
Amines
3 Citations

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, H. E., Angus, S. P., Bo, T., Roques, J., Tagliatela, A. C., Darr, D. B., Karagoz, K., Sciaky, N., Gatza, M. L., Sharpless, N. E., Johnson, G. L. & Bear, J. E., Jan 15 2018, In : Cancer Research. 78, 2, p. 542-557 16 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Neoplasms
Pharmaceutical Preparations
Therapeutics