• 7985 Citations
  • 44 h-Index
1984 …2018
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  • 16 Similar Profiles
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Factor IX Medicine & Life Sciences
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Factor X Medicine & Life Sciences

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Projects 1997 2018

Prohemostatic compounds

Monroe, D. M.

Industry Sponsor

8/1/152/1/16

Project: Research project

Hemophilia A
Tranexamic Acid
Factor IX
Blood Coagulation Factors
Factor VIII

SBIR: Chimeric FVIIa

Stafford, D. W. & Monroe, D. M.

Industry Sponsor

4/1/159/30/16

Project: Research project

Hemophilia A
Hemorrhage
Factor VIII
Half-Life
Factor VIIa
Hemophilia B
Hematoma
Hemorrhage
Joints
Wounds and Injuries
Antithrombins
Thrombin
Heparin
Antithrombin III
Thoracic Surgery

Research Output 1984 2018

In vitro characterization of MOD-5014, a novel long-acting carboxy-terminal peptide (CTP)-modified activated FVII

Bar-Ilan, A., Livnat, T., Hoffmann, M., Binder, L., Zakar, M., Guy, R., Felikman, Y., Moschcovich, L., Shenkman, B., Monroe, D., Hershkovitz, O., Kenet, G. & Hart, G., May 1 2018, In : Haemophilia. 24, 3, p. 477-486 10 p.

Research output: Contribution to journalArticle

Hemorrhagic Disorders
Hemophilia A
Blood Platelets
Thrombin
Peptides
6 Citations

Abnormal joint and bone wound healing in hemophilia mice is improved by extending factor IX activity after hemarthrosis

Sun, J., Hua, B., Livingston, E. W., Taves, S., Johansen, P. B., Hoffman, M., Ezban, M., Monroe, D. M., Bateman, T. A. & Monahan, P. E., Apr 13 2017, In : Blood. 129, 15, p. 2161-2171 11 p.

Research output: Contribution to journalArticle

Hemarthrosis
Hemophilia B
Animal Disease Models
Factor IX
Degassing

Harold Ross Roberts, MD, 1930-2017

Monroe, D. M. & Key, N. S., Jan 1 2017, (Accepted/In press) In : Haemophilia.

Research output: Contribution to journalArticle

Impact of non-Vitamin K antagonist oral anticoagulants from a basic science perspective

Hoffman, M. & Monroe, D. M., Jan 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 10, p. 1812-1818 7 p.

Research output: Contribution to journalArticle

Drug Dose Response Relationship
Competitive Binding
Antithrombins
Vitamin K
Thromboembolism
28 Citations

In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps

Noubouossie, D. F., Whelihan, M. F., Yu, Y. B., Sparkenbaugh, E., Pawlinski, R., Monroe, D. M. & Key, N. S., Feb 23 2017, In : Blood. 129, 8, p. 1021-1029 9 p.

Research output: Contribution to journalArticle

Coagulation
Histones
Neutrophils
Chemical activation
DNA