• 4620 Citations
  • 36 h-Index
1983 …2020
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DNA Medicine & Life Sciences
DNA-Directed RNA Polymerases Medicine & Life Sciences
DNA Mismatch Repair Medicine & Life Sciences
Atomic Force Microscopy Medicine & Life Sciences
Proteins Medicine & Life Sciences
Transcription Chemical Compounds
Repair Chemical Compounds
Conformations Chemical Compounds

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Projects 1996 2020

DNA Repair
Biological Models
Saccharomyces cerevisiae
Proteins
Yeasts
Trinucleotide Repeat Expansion
Nucleic Acid Conformation
DNA Mismatch Repair
DNA
Myotonic Dystrophy
Mutation
Muscle Neoplasms
Genetic Code
Cell Physiological Phenomena
Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Research Output 1983 2018

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

LeBlanc, S. J., Gauer, J. W., Hao, P., Case, B. C., Hingorani, M. M., Weninger, K. R. & Erie, D. A., Nov 16 2018, In : Nucleic acids research. 46, 20, p. 10782-10795 14 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
DNA
Proteins
DNA Replication
Base Pairing

Regulatory control of DNA end resection by Sae2 phosphorylation

Cannavo, E., Johnson, D., Andres, S. N., Kissling, V. M., Reinert, J. K., Garcia, V., Erie, D. A., Hess, D., Thomä, N. H., Enchev, R. I., Peter, M., Williams, R. S., Neale, M. J. & Cejka, P., Dec 1 2018, In : Nature Communications. 9, 1, 4016.

Research output: Contribution to journalArticle

phosphorylation
deoxyribonucleic acid
Phosphorylation
DNA
Double-Stranded DNA Breaks
2 Citations

Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates

Bellendir, S. P., Rognstad, D. J., Morris, L. P., Zapotoczny, G., Walton, W. G., Redinbo, M. R., Ramsden, D. A., Sekelsky, J. & Erie, D. A., May 19 2017, In : Nucleic acids research. 45, 9, p. 5333-5348 16 p.

Research output: Contribution to journalArticle

Cruciform DNA
Endonucleases
DNA Repair
DNA Damage
Drosophila

Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein–DNA Complexes That Carry Out DNA Repair

LeBlanc, S., Wilkins, H., Li, Z., Kaur, P., Wang, H. & Erie, D. A., Jan 1 2017, Methods in Enzymology. Academic Press Inc., p. 187-212 26 p. (Methods in Enzymology; vol. 592).

Research output: Chapter in Book/Report/Conference proceedingChapter

Atomic Force Microscopy
DNA Repair
DNA
Proteins
Nucleic Acid Conformation
15 Citations

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

Harrison, J. S., Cornett, E. M., Goldfarb, D., Darosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Erie, D. A., Major, M. B., Klevit, R. E., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B., Sep 6 2016, In : eLife. 5, Se, e17101.

Research output: Contribution to journalArticle

Ubiquitination
DNA Methylation
Histones
Chemical activation
DNA