Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Epoxy Compounds Medicine & Life Sciences
Caco-2 Cells Medicine & Life Sciences
Liver Microsomes Medicine & Life Sciences
Metabolites Chemical Compounds
Metabolism Chemical Compounds
Methylcholanthrene Medicine & Life Sciences
Liver Chemical Compounds
Cytochrome P-450 Enzyme System Medicine & Life Sciences

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Projects 2000 2016

Research Output 1973 2016

A Tribute to Ronald T. Borchardt - Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Schowen, K. B., Schowen, R. L., Borchardt, S. E., Borchardt, P. M., Artursson, P., Audus, K. L., Augustijns, P., Nicolazzo, J. A., Raub, T. J., Schöneich, C., Siahaan, T. J., Takakura, Y., Thakker, D. R. & Wolfe, M. S. Feb 1 2016 In : Journal of Pharmaceutical Sciences. 105, 2, p. 370-385 16 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Laboratory Personnel
Mentors
Anniversaries and Special Events
8 Citations

Cation-selective transporters are critical to the AMPK-mediated antiproliferative effects of metformin in human breast cancer cells

Cai, H., Zhang, Y., Han, T., Everett, R. S. & Thakker, D. R. May 1 2016 In : International Journal of Cancer. 138, 9, p. 2281-2292 12 p.

Research output: Contribution to journalArticle

Metformin
Adenosine Monophosphate
Protein Kinases
Cations
Breast Neoplasms
8 Citations
dimethylaniline monooxygenase (N-oxide forming)
Liver Microsomes
Liquid Chromatography
Proteomics
Proteins
7 Citations

Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis

Proctor, W. R., Ming, X., Bourdet, D., Han, T. K., Everett, R. S. & Thakker, D. R. Feb 1 2016 In : Journal of Pharmaceutical Sciences. 105, 2, p. 484-496 13 p.

Research output: Contribution to journalReview article

Intestines
Tight Junction Proteins
Cations
Anions
Pressure
32 Citations

Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayerss

Han, T., Proctor, W. R., Costales, C. L., Cai, H., Everett, R. S. & Thakker, D. R. Mar 1 2015 In : Journal of Pharmacology and Experimental Therapeutics. 352, 3, p. 519-528 10 p.

Research output: Contribution to journalArticle

Caco-2 Cells
Metformin
Cations
Membrane Transport Proteins
Intestinal Absorption