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  • 8 Similar Profiles
Insulin-Like Growth Factor I Medicine & Life Sciences
Insulin-Like Growth Factor Binding Proteins Medicine & Life Sciences
Somatomedins Medicine & Life Sciences
Insulin-Like Growth Factor Binding Protein 5 Medicine & Life Sciences
Insulin-Like Growth Factor Binding Protein 2 Medicine & Life Sciences
Smooth Muscle Myocytes Medicine & Life Sciences
Growth Hormone Medicine & Life Sciences
Insulin-Like Growth Factor Binding Protein 1 Medicine & Life Sciences

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Projects 1980 2017

Diabetic Retinopathy
Integrins
Insulin-Like Growth Factor I
Proteins
Antibodies
Parathyroid Hormone
Respiration
Glycolysis
Osteogenesis
Energy Metabolism
Bone and Bones
Peptides
Osteogenesis
Osteoporosis
Bone Density
Diabetic Retinopathy
Integrins
Antibodies
Insulin-Like Growth Factor I
Endothelial Cells
Insulin-Like Growth Factor Binding Protein 2
Bone Remodeling
Estrogens
Osteoblasts
Insulin-Like Growth Factor II

Research Output 1972 2017

1 Citations

Down-regulation of insulin receptor substrate 1 during hyperglycemia induces vascular smooth muscle cell dedifferentiation

Xi, G., Wai, C., White, M. F. & Clemmons, D. R. Feb 3 2017 In : Journal of Biological Chemistry. 292, 5, p. 2009-2020 12 p.

Research output: Contribution to journalArticle

Cell Dedifferentiation
Insulin Receptor Substrate Proteins
Vascular Smooth Muscle
Hyperglycemia
Smooth Muscle Myocytes
15 Citations

IGF-I and IGFBP-2 stimulate AMPK activation and autophagy, which are required for osteoblast differentiation

Xi, G., Rosen, C. J. & Clemmons, D. R. Jan 1 2016 In : Endocrinology. 157, 1, p. 268-281 14 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 2
AMP-Activated Protein Kinases
Autophagy
Osteoblasts
Insulin-Like Growth Factor I
6 Citations

IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling during Osteoblast Differentiation

Xi, G., Shen, X., Rosen, C. J. & Clemmons, D. R. Jun 1 2016 In : Journal of Bone and Mineral Research. 31, 6, p. 1300-1314 15 p.

Research output: Contribution to journalArticle

Class 5 Receptor-Like Protein Tyrosine Phosphatases
Insulin-Like Growth Factor Binding Protein 2
Insulin Receptor Substrate Proteins
Osteoblasts
Insulin-Like Growth Factor I
18 Citations

Role of IGF Binding Proteins in Regulating Metabolism

Clemmons, D. R. Jun 1 2016 In : Trends in Endocrinology and Metabolism. 27, 6, p. 375-391 17 p.

Research output: Contribution to journalReview article

Insulin-Like Growth Factor Binding Proteins
Somatomedins
Insulin-Like Growth Factor I
Insulin-Like Growth Factor II
Membrane Proteins
20 Citations

Budesonide foam induces remission in patients with mild to moderate ulcerative proctitis and ulcerative proctosigmoiditis

Sandborn, W. J., Bosworth, B., Zakko, S., Gordon, G. L., Clemmons, D. R., Golden, P. L., Rolleri, R. L., Yu, J., Barrett, A. C., Bortey, E., Paterson, C. & Forbes, W. P. Jan 1 2015 In : Gastroenterology. 148, 4, p. 740-750.e2

Research output: Contribution to journalArticle

Proctocolitis
Proctitis
Budesonide
Placebos
Adrenal Cortex Hormones