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  • 7 Similar Profiles
Tryptophan-tRNA Ligase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Proteins Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Tryptophan Medicine & Life Sciences
Amino Acids Medicine & Life Sciences
Amino Acyl-tRNA Synthetases Medicine & Life Sciences
Catalysis Medicine & Life Sciences

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Projects 1994 2019

Research Output 1972 2017

2 Citations
Mutagenesis
mutagenesis
Tryptophan-tRNA Ligase
Free energy
Activation energy
3 Citations

Combining multi-mutant and modular thermodynamic cycles to measure energetic coupling networks in enzyme catalysis

Carter, C. W., Chandrasekaran, S. N., Weinreb, V., Li, L. & Williams, T. May 1 2017 In : Structural Dynamics. 4, 3, 032101

Research output: Research - peer-reviewArticle

Tryptophan-tRNA Ligase
Catalysis
Thermodynamics
Enzymes
Transfer RNA
8 Citations

A modified PATH algorithm rapidly generates transition states comparable to those found by other well established algorithms

Chandrasekaran, S. N., Das, J., Dokholyan, N. V. & Carter, C. W. Jan 1 2016 In : Structural Dynamics. 3, 1, 012101

Research output: Research - peer-reviewArticle

Proteins
Structural properties
Crystal structure
Trajectories
proteins
2 Citations
Tryptophan-tRNA Ligase
Ground state
Enzymes
RNA Precursors
Amino Acyl-tRNA Synthetases
5 Citations

Selective inhibition of bacterial tryptophanyl-tRNA synthetases by indolmycin is mechanism-based

Williams, T. L., Yin, Y. W. & Carter, C. W. Jan 1 2016 In : Journal of Biological Chemistry. 291, 1, p. 255-265 11 p.

Research output: Research - peer-reviewArticle

Tryptophan-tRNA Ligase
indolmycin
Tryptophan
Adenosine Triphosphate
Stabilization