• 98771 Citations
  • 110 h-Index
1981 …2022
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  • 2 Similar Profiles
Breast Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Breast Medicine & Life Sciences
Triple Negative Breast Neoplasms Medicine & Life Sciences
Estrogen Receptors Medicine & Life Sciences
Transcriptome Medicine & Life Sciences

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Projects 1981 2022

Obesity
Neoplasms
Breast Neoplasms
Clinical Trials
Pancreatic Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Brain
Gene Expression
Point Mutation
Breast Neoplasms
Neoplasms
Neoplastic Stem Cells
Proteomics
Therapeutics

Research Output 1988 2018

A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

Hollern, D. P., Contreras, C. M., Dance-Barnes, S., Silva, G. O., Pfefferle, A. D., Xiong, J., Darr, D. B., Usary, J., Mott, K. R. & Perou, C. M., Jan 1 2018, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasms
Recombinases
Comparative Genomic Hybridization
Sequence Deletion
1 Citations

A Phase I Trial of the PI3K Inhibitor Buparlisib Combined With Capecitabine in Patients With Metastatic Breast Cancer

McRee, A. J., Marcom, P. K., Moore, D. T., Zamboni, W. C., Kornblum, Z. A., Hu, Z., Phipps, R., Anders, C. K., Reeder-Hayes, K., Carey, L. A., Weck, K. E., Perou, C. M. & Dees, E. C., Aug 1 2018, In : Clinical Breast Cancer. 18, 4, p. 289-297 9 p.

Research output: Contribution to journalArticle

Phosphotransferases
Breast Neoplasms
Maximum Tolerated Dose
Pharmacokinetics
Aspartate Aminotransferases
19 Citations

Asparagine bioavailability governs metastasis in a model of breast cancer

Knott, S. R. V., Wagenblast, E., Khan, S., Kim, S. Y., Soto, M., Wagner, M., Turgeon, M. O., Fish, L., Erard, N., Gable, A. L., MacEli, A. R., DIckopf, S., Papachristou, E. K., D'Santos, C. S., Carey, L. A., Wilkinson, J. E., Harrell, J. C., Perou, C. M., Goodarzi, H., Poulogiannis, G. & 1 othersHannon, G. J., Feb 15 2018, In : Nature. 554, 7692, p. 378-381 4 p.

Research output: Contribution to journalArticle

Asparagine
Aspartate-Ammonia Ligase
Biological Availability
Breast Neoplasms
Neoplasm Metastasis

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

An, Y., Adams, J. R., Hollern, D. P., Zhao, A., Chang, S. G., Gams, M. S., Chung, P. E. D., He, X., Jangra, R., Shah, J. S., Yang, J., Beck, L. A., Raghuram, N., Kozma, K. J., Loch, A. J., Wang, W., Fan, C., Done, S. J., Zacksenhaus, E., Guidos, C. J. & 2 othersPerou, C. M. & Egan, S. E., Oct 16 2018, In : Cell Reports. 25, 3, p. 702-714.e6

Research output: Contribution to journalArticle

Lobular Carcinoma
Tumors
Breast
Transcription
Infiltration
1 Citations

Clinical implications of the non-luminal intrinsic subtypes in hormone receptor-positive breast cancer

Cejalvo, J. M., Pascual, T., Fernández-Martínez, A., Brasó-Maristany, F., Gomis, R. R., Perou, C. M., Muñoz, M. & Prat, A., Jun 1 2018, In : Cancer Treatment Reviews. 67, p. 63-70 8 p.

Research output: Contribution to journalReview article

Hormones
Breast Neoplasms
Gene Expression Profiling
Protein-Tyrosine Kinases
Estrogens